Ulrich Knigge
Guest researcher
Cluster for Molecular Imaging
Blegdamsvej 3, 2200 København N.
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Nordic Guidelines 2010 for diagnosis and treatment of gastroenteropancreatic neuroendocrine tumours
Janson, E. T., Sørbye, H., Welin, S., Federspiel, B. H., Grønbaek, H., Hellman, P., Mathisen, O., Mortensen, Jann, Sundin, A., Thiis-Evensen, E., Välimäki, M. J., Oberg, K. & Knigge, Ulrich, 1 Aug 2010, In: Acta Odontologica Scandinavica. 49, 6, p. 740-56 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
Janson, E. T., Sorbye, H., Welin, S., Federspiel, B., Grønbæk, H., Hellman, P., Ladekarl, M., Langer, Seppo W., Mortensen, Jann, Schalin-Jäntti, C., Sundin, A., Sundlöv, A., Thiis-Evensen, E. & Knigge, Ulrich, 2014, In: Acta Oncologica. 53, 10, p. 1284-1297 14 p.Research output: Contribution to journal › Review › Research › peer-review
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On the effects of human galanin in man
Holst, Jens Juul, Bersani, M., Hvidberg, A., Knigge, Ulrich, Christiansen, E. M., Madsbad, Sten, Harling, H. & Kofod, H., 1993, In: Diabetologia. 36, 7, p. 653-657 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Outlook for 615 Small Intestinal Neuroendocrine Tumor Patients: Recurrence Risk after Surgery and Disease-Specific Survival in Advanced Disease
Slott, C., Langer, Seppo W., Møller, S., Krogh, Jesper, Klose, M., Hansen, C. P., Kjær, Andreas, Holmager, P., Garbyal, Rajendra Singh, Knigge, Ulrich & Andreassen, Mikkel, 2024, In: Cancers. 16, 1, 16 p., 204.Research output: Contribution to journal › Journal article › Research › peer-review
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P53, Somatostatin receptor 2a and Chromogranin A immunostaining as prognostic markers in high grade gastroenteropancreatic neuroendocrine neoplasms
Nielsen, K., Binderup, Tina, Langer, Seppo W., Kjær, Andreas, Knigge, P., Grøndahl, V., Melchior, L., Federspiel, B. & Knigge, Ulrich, 2020, In: BMC Cancer. 20, 14 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
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PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3
Ali, A. S., Langer, Seppo W., Federspiel, B., Hjortland, G. O., Grønbæk, H., Ladekarl, M., Welin, S., Weber Vestermark, L., Arola, J., Osterlund, P., Knigge, Ulrich, Sørbye, H., Micke, P., Grimelius, L., Grönberg, M. & Tiensuu Janson, E., 2020, In: PLoS ONE. 15, 12, 12 p., e0243900.Research output: Contribution to journal › Journal article › Research › peer-review
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PET tracers for somatostatin receptor imaging of neuroendocrine tumors: current status and review of the literature
Johnbeck, C. B., Knigge, Ulrich & Kjær, Andreas, Nov 2014, In: Future Oncology. 10, 14, p. 2259-2277 19 p.Research output: Contribution to journal › Review › Research › peer-review
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Pancreatic Islet Cell Tumors
Knigge, Ulrich, Andreassen, Mikkel, Federspiel, B., Hansen, C. P., Kjær, Andreas & Langer, S. W., 2018, Encyclopedia of Endocrine Diseases. Huhtaniemi, I. & Martini, L. (eds.). 2. ed. Elsevier, p. 626-634Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Peptide receptor radionuclide therapy in gastroenteropancreatic NEN G3: a multicenter cohort study
Carlsen, E. A., Fazio, N., Granberg, D., Grozinsky-Glasberg, S., Ahmadzadehfar, H., Grana, C. M., Zandee, W. T., Cwikla, J., Walter, M. A., Oturai, P. S., Rinke, A., Weaver, A., Frilling, A., Gritti, S., Arveschoug, A. K., Meirovitz, A., Knigge, Ulrich & Sorbye, H., 2019, In: Endocrine-Related Cancer. 26, 2, p. 227-239Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide receptor radionuclide therapy with Y-DOTATOC and (177)Lu-DOTATOC in advanced neuroendocrine tumors: results from a Danish cohort treated in Switzerland
Pfeifer, A. K., Gregersen, T., Grønbæk, H., Hansen, C. P., Müller-Brand, J., Herskind Bruun, K., Krogh, K., Kjær, Andreas & Knigge, Ulrich, 2011, In: Neuroendocrinology. 93, 3, p. 189-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma protein biomarkers for the detection of pancreatic neuroendocrine tumors and differentiation from small intestinal neuroendocrine tumors
The Nordic NET Biomarker Group, T. N. N. B. G., 2022, In: Journal of Neuroendocrinology. 34, 7, 9 p., e13176.Research output: Contribution to journal › Journal article › Research › peer-review
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Postoperative morbidity among symptom-free alcohol misusers
Tønnesen, H., Petersen, K. R., Højgaard, Liselotte, Stokholm, K. H., Nielsen, H. J., Knigge, Ulrich & Kehlet, Henrik, 8 Aug 1992, In: Lancet Oncology. 340, 8815, p. 334-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): The NORDIC NEC study
Sorbye, H., Welin, S., Langer, Seppo W., Vestermark, L. W., Holt, N., Osterlund, P., Dueland, S., Hofsli, E., Guren, M. G., Ohrling, K., Birkemeyer, E., Thiis-Evensen, E., Biagini, M., Gronbaek, H., Soveri, L. M., Olsen, I. H., Federspiel, B., Assmus, J., Janson, E. T. & Knigge, Ulrich, 2013, In: Annals of Oncology. 24, 1, p. 152-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal poorly differentiated neuroendocrine carcinoma: The NORDIC NEC study
Sorbye, H., Welin, S., Langer, Seppo W., Vestermark, L. W., Holt, N., Osterlund, P. J., Dueland, S., Hofsli, E., Guren, M. G., Ohrling, K., Birkemeyer, E., Thiis-Evensen, E., Biagini, M., Gronbaek, H., Soveri, L., Olsen, I. H., Federspiel, B., Assmus, J., Janson, E. T. & Knigge, Ulrich, 20 May 2012, In: Journal of Clinical Oncology. 30, 15, 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
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Primary Hyperparathyroidism in Young People. When Should We Perform Genetic Testing for Multiple Endocrine Neoplasia 1 (MEN-1)?
Lassen, T. H., Friis-Hansen, L. J., Rasmussen, Å. K., Knigge, Ulrich & Feldt-Rasmussen, Ulla, Nov 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 11, p. 3983-3987 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prognostic Thresholds of Mitotic Count and Ki-67 Labeling Index for Recurrence and Survival in Lung Atypical Carcinoids
Soldath, Patrick, Bianchi, D., Manfredini, B., Kjær, Andreas, Langer, Seppo W., Knigge, Ulrich, Melfi, F., Filosso, P. L. & Petersen, René Horsleben, 2024, In: Cancers. 16, 3, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prognostic thresholds of FDG-PET SUVmean and SUVmax for survival and nodal involvement in lung neuroendocrine neoplasms
Soldath, Patrick, Binderup, Tina, Kjær, Andreas, Knigge, Ulrich, Langer, Seppo W. & Petersen, René Horsleben, 2024, In: European Journal of Cardio-thoracic Surgery. 65, 2, 13 p., ezae030.Research output: Contribution to journal › Journal article › Research › peer-review
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Prognostic value of 18F-FLT PET in patients with neuroendocrine neoplasms: A prospective head-to-head comparison with 18F-FDG PET and Ki-67 in 100 patients
Johnbeck, C. B., Knigge, Ulrich, Langer, Seppo W., Loft, A., Berthelsen, A. K., Federspiel, B., Binderup, Tina & Kjær, Andreas, 1 Dec 2016, In: Journal of Nuclear Medicine. 57, 12, p. 1851-1857 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prospective Phase II Trial of [68Ga]Ga-NODAGA-E[c(RGDyK)]2 PET/CT Imaging of Integrin αvβ3 for Prognostication in Patients with Neuroendocrine Neoplasms
Carlsen, E. A., Loft, M., Loft, A., Czyzewska, D., Andreassen, Mikkel, Langer, Seppo W., Knigge, Ulrich & Kjær, Andreas, 2023, In: The Journal of Nuclear Medicine. 64, 2, p. 252-259Research output: Contribution to journal › Journal article › Research › peer-review
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Prospective Study of Chromogranin A as a Predictor of Progression in Patients with Pancreatic, Small-Intestinal, and Unknown Primary Neuroendocrine Tumors
Dam, G., Grønbæk, H., Sorbye, H., Thiis Evensen, E., Paulsson, B., Sundin, A., Jensen, C., Ebbesen, D., Knigge, Ulrich & Tiensuu Janson, E., 2020, In: Neuroendocrinology. 110, 3-4, p. 217-224 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prospective phase II trial of prognostication by 68Ga-NOTA-AE105 uPAR PET in patients with neuroendocrine neoplasms: Implications for uPAR targeted therapy
Carlsen, Esben Andreas, Loft, Mathias Hougaard, Loft, A., Berthelsen, A. K., Langer, Seppo W., Knigge, Ulrich & Kjær, Andreas, 2022, In: Journal of Nuclear Medicine. 63, 9, p. 1371-1377Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative gene expression of somatostatin receptors and noradrenaline transporter underlying scintigraphic results in patients with neuroendocrine tumors.
Binderup, Tina, Knigge, Ulrich, Mellon Mogensen, A., Palnaes Hansen, C. & Kjær, Andreas, 2008, In: Neuroendocrinology. 87, 4, p. 223-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative gene-expression of the tumor angiogenesis markers vascular endothelial growth factor, integrin alphaV and integrin beta3 in human neuroendocrine tumors
Oxboel, J., Binderup, Tina, Knigge, Ulrich & Kjær, Andreas, 2009, In: Oncology Reports. 21, 3, p. 769-75 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Radiofrekvensablation af insulinomer i pancreas
Jansen, C., Vilmann, Peter, Brink, L., Andreassen, Mikkel, Knigge, Ulrich, Hansen, C. P. & Kovacevic, B., 2022, In: Ugeskrift for Laeger. 184, 46, 7 p., V06220416.Research output: Contribution to journal › Review › Research › peer-review
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Radionuklidbehandling af neuroendokrine tumorer
Mortensen, Jann, Oturai, P., Højgaard, Liselotte, Knigge, Ulrich, Hansen, C. P., Martiný, L., Rasmussen, P., Kjær, Andreas & Oturai, P. S., 25 Oct 2010, In: Ugeskrift for Laeger. 172, 43, p. 2950-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recurrence-Free Survival and Disease-Specific Survival in Patients with Pancreatic Neuroendocrine Neoplasms: A Single-Center Retrospective Study of 413 Patients
Møller, S., Langer, Seppo W., Slott, C., Krogh, Jesper, Hansen, C. P., Kjær, Andreas, Holmager, P., Klose, M., Garbyal, Rajendra Singh, Knigge, Ulrich & Andreassen, Mikkel, 2023, In: Cancers. 16, 1, 14 p., 100.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of 64Cu-DOTATATE activity dose for somatostatin receptor PET imaging of patients with neuroendocrine neoplasms
Loft, Mathias Hougaard, Carlsen, Esben Andreas, Johnbeck, C. B., Jensen, C. V., Andersen, Flemming Littrup, Langer, Seppo W., Otorai, P., Knigge, Ulrich & Kjær, Andreas, 2022, In: Journal of Neuroendocrinology. 34, S1, p. 151-151 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Resection of Liver Metastases in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Carcinomas: A Nordic Multicenter Study
Galleberg, R. B., Knigge, Ulrich, Janson, E. T., Vestermark, L. W., Haugvik, S. P., Ladekarl, M., Langer, Seppo W., Grønbæk, H., Osterlund, P., Hjortland, G., Assmus, J., Tang, L., Perren, A. & Sorbye, H., 2017, In: Neuroendocrinology. 105, p. 264 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
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Responses to Medical Treatment in 192 Patients with Pancreatic Neuroendocrine Neoplasms Referred to the Copenhagen Neuroendocrine Tumour Centre in 2000–2020
Petersen, S. S., Møller, S., Slott, C., Krogh, Jesper, Hansen, C. P., Kjær, Andreas, Holmager, P., Oturai, P., Garbyal, Rajendra Singh, Langer, Seppo W., Knigge, Ulrich & Andreassen, Mikkel, 2024, In: Cancers. 16, 6, 16 p., 1190.Research output: Contribution to journal › Journal article › Research › peer-review
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Results after surgical treatment of liver metastases in patients with high-grade gastroenteropancreatic neuroendocrine carcinomas
Galleberg, R. B., Knigge, Ulrich, Tiensuu Janson, E., Vestermark, L. W., Haugvik, S., Ladekarl, M., Langer, Seppo W., Grønbæk, H., Österlund, P., Hjortland, G. O., Assmus, J., Tang, L., Perren, A. & Sorbye, H., 2017, In: European Journal of Surgical Oncology. 43, 9, p. 1682-1689Research output: Contribution to journal › Journal article › Research › peer-review
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Results of 252 Patients with Bronchopulmonary Neuroendocrine Tumors Treated at the Copenhagen NET Centre of Excellence
Groendahl, Knigge, Ulrich, Langer, Seppo W., Kjær, Andreas, Federspiel, B., Petersen, René Horsleben, Binderup, Tina & Nielsen, K., 2018, p. 289-289. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Rubidium-82 uptake in metastases from neuroendocrine tumors: No flow response to adenosine
Hasbak, P., Enevoldsen, L. H., Fosbøl, M. Ø., Skovgaard, D., Knigge, Ulrich & Kjær, Andreas, Aug 2016, In: Journal of Nuclear Cardiology. 23, 4, p. 840-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective inhibition of magnocellular vasopressin neurons by hypoosmolality: Effect on histamine- and stress-induced secretion of adrenocorticotropin and prolactin
Kjær, Andreas, Knigge, Ulrich, Jørgensen, H. & Warberg, J., 1998, In: Neuroendocrinology. 67, p. 330-335Research output: Contribution to journal › Journal article › Research › peer-review
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Semi-automatic tumor delineation for evaluation of 64Cu-DOTATATE PET/CT in patients with neuroendocrine neoplasms: prognostication based on lowest lesion uptake and total tumor volume
Carlsen, Esben Andreas, Johnbeck, C. B., Loft, Mathias Hougaard, Pfeifer, A., Oturai, P., Langer, Seppo W., Knigge, Ulrich, Ladefoged, C. N. & Kjær, Andreas, 2021, In: The Journal of Nuclear Medicine. 62, 11, p. 1564-1570Research output: Contribution to journal › Journal article › Research › peer-review
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Serotonergic involvement in stress-induced ACTH release
Jørgensen, H., Knigge, Ulrich, Kjær, Andreas, Vadsholt, T. & Warberg, J., 1998, In: Brain Research. 811, p. 10-20Research output: Contribution to journal › Journal article › Research › peer-review
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Serotonergic involvement in stress-induced vasopressin and oxytocin secretion.
Jørgensen, H., Knigge, Ulrich, Kjær, Andreas & Warberg, J., 2002, In: European Journal of Endocrinology. 147, 6, p. 815-24 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serotonergic stimulation of Corticotropin-Releasing Hormone and Pro-Opiomelanocortin gene expression
Jørgensen, H., Knigge, Ulrich, Kjær, Andreas, Møller, M. & Warberg, J., 2002, In: Journal of Neuroendocrinology. 788-795, p. 14Research output: Contribution to journal › Journal article › Research › peer-review
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Serotonin receptors involved in vasopressin and oxytocin secretion
Jørgensen, H., Riis, M., Knigge, Ulrich, Kjær, Andreas & Warberg, J., 1 Mar 2003, In: Journal of Neuroendocrinology. 15, 3, p. 242-249 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Serotonin stimulates hypothalamic gene expression and local release of neurohypophysial peptides
Jørgensen, H., Kjær, Andreas, Knigge, Ulrich, Møller, M. & Warberg, J., 2003, In: Journal of Neuroendocrinology. 15, p. 564-571Research output: Contribution to journal › Journal article › Research › peer-review
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Somatostatin analogue treatment primarily induce miRNA expression changes and up-regulates growth inhibitory miR-7 and miR-148a in neuroendocrine cells
Døssing, K. B. V., Kjær, C., Vikeså, J., Binderup, Tina, Knigge, Ulrich, Culler, M. D., Kjær, Andreas, Federspiel, B. & Friis-Hansen, Lennart Jan, 2018, In: Genes. 9, 7, 17 p., 337.Research output: Contribution to journal › Journal article › Research › peer-review
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Somatostatin-Immunoreactive Pancreaticoduodenal Neuroendocrine Neoplasms: Twenty-three cases evaluated according to the WHO 2010 Classification
Engelund Luna, I., Monrad, N., Binderup, Tina, Boisen Thoegersen, C., Hilsted, Linda, Jensen, C., Federspiel, B. & Knigge, Ulrich, 2016, In: Neuroendocrinology. 103, 5, p. 567-77 11 p., 000441605.Research output: Contribution to journal › Journal article › Research › peer-review
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Surgery for GEP-NETs
Knigge, Ulrich & Hansen, C. P., Dec 2012, In: Best Practice & Research: Clinical Gastroenterology. 26, 6, p. 819-31 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Surgery in Patients with Gastro-Entero-Pancreatic Neuroendocrine Carcinomas, Neuroendocrine Tumors G3 and High Grade Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms
Holmager, P., Langer, Seppo W., Kjær, Andreas, Ringholm, L., Garbyal, Rajendra Singh, Pommergaard, Hans-Christian L, Hansen, C. P., Federspiel, B., Andreassen, Mikkel & Knigge, Ulrich, 2022, In: Current Treatment Options in Oncology. 23, 6, p. 806-817 12 p.Research output: Contribution to journal › Review › Research › peer-review
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Surgery of the primary tumour in 201 patients with high-grade gastroenteropancreatic neuroendocrine and mixed neuroendocrine-non-neuroendocrine neoplasms
Pommergaard, H., Nielsen, K., Sorbye, H., Federspiel, B., Tabaksblat, E. M., Vestermark, L. W., Janson, E. T., Hansen, C. P., Ladekarl, M., Garresori, H., Hjortland, G. O., Sundlöv, A., Galleberg, R., Knigge, P., Kjær, Andreas, Langer, Seppo W. & Knigge, Ulrich, 2021, In: Journal of Neuroendocrinology. 33, 5, 12 p., e12967.Research output: Contribution to journal › Journal article › Research › peer-review
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Surgical Management, Preoperative Tumor Localization, and Histopathology of 80 Patients Operated on for Insulinoma
Andreassen, Mikkel, Ilett, E., Wiese, D., Slater, E. P., Klose, M., Hansen, C. P., Gercke, N., Langer, Seppo W., Kjaer, A., Maurer, E., Federspiel, B., Kann, P. H., Bartsch, D. K. & Knigge, Ulrich, Dec 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6129-6138Research output: Contribution to journal › Journal article › Research › peer-review
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Surgical management, pre-operative tumor localization and histopathology of 80 patients operated for insulinoma.
Andreassen, Mikkel, Ilett, E., Wiese, D., Slater, E., Klose, M., Hansen, C., Gercke, N., Langer, Seppo W., Kjær, Andreas, Maurer, E., Federspiel, B., Kann, P., Bartsch, D. & Knigge, Ulrich, 2019, In: Journal of Clinical Endocrinology and Metabolism. p. 6129–6138Research output: Contribution to journal › Journal article › Research › peer-review
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Synchronous gastric neuroendocrine carcinoma and hepatocellular carcinoma
tds797, tds797, Henriksen, B. M., Hansen, C. P. & Knigge, Ulrich, 2009Research output: Other contribution › Research
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Temozolomide as 2nd-3rd Line Treatment of Patients with Poorly Differentiated Neuroendocrine Carcinomas
Olsen, I. H., Federspiel, B., Kjær, Andreas, Hansen, C. P., Knigge, Ulrich & Langer, Seppo W., 2011, p. 38-38. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Temozolomide as second or third line treatment of patients with neuroendocrine carcinomas
Olsen, I. M. H., Sørensen, Jens Benn, Federspiel, B., Kjær, Andreas, Hansen, C. P., Knigge, Ulrich & Langer, S. W., 2012, In: Scientific World Journal. 2012, p. 170496 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The prolactin releasing effect of histamine is unrelated to its vascular action
Kjær, Andreas, Knigge, Ulrich & Warberg, J., 1990, In: Acta Endocrinologica. 122, 1, p. 49-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 916819
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Down-regulation of miR-129-5p and the let-7 family in neuroendocrine tumors and metastases leads to up-regulation of their targets Egr1, G3bp1, Hmga2 and Bach1
Research output: Contribution to journal › Journal article › Research › peer-review
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464
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PET tracers for somatostatin receptor imaging of neuroendocrine tumors: current status and review of the literature
Research output: Contribution to journal › Review › Research › peer-review
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155
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Somatostatin analogue treatment primarily induce miRNA expression changes and up-regulates growth inhibitory miR-7 and miR-148a in neuroendocrine cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published