Ulrich Knigge
Guest researcher
Cluster for Molecular Imaging
Blegdamsvej 3, 2200 København N.
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Expression of p53 protein in high-grade gastroenteropancreatic neuroendocrine carcinoma
Ali, A. S., Grönberg, M., Federspiel, B., Scoazec, J. Y., Hjortland, G. O., Grønbæk, H., Ladekarl, M., Langer, Seppo W., Welin, S., Vestermark, L. W., Arola, J., Österlund, P., Knigge, Ulrich, Sorbye, H., Grimelius, L. & Janson, E. T., Nov 2017, In: PLOS ONE. 12, 11, 15 p., e0187667.Research output: Contribution to journal › Journal article › Research › peer-review
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FDG-PET Is Superior to WHO Grading in Predicting Overall Survival of Patients with Neuroendocrine Tumors: A Prospective Study of 172 Patients
Binderup, Tina, Johnbeck, C. B., Loft, A., Berthelsen, A. K., Federspiel, B., Langer, Seppo W., Knigge, Ulrich & Kjær, Andreas, 2017, In: Neuroendocrinology. 105, p. 164-164 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
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Feasibility and Implication of Routine NGS Analysis in Neuroendocrine Carcinomas
Knigge, Ulrich, Federspiel, B., Andreassen, Mikkel, Kjær, Andreas & Langer, Seppo W., 2017, In: Neuroendocrinology. 105, S1, p. 26-26 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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First-In-Human Study of [68Ga]Ga-NODAGA-E[c(RGDyK)]2 PET for Integrin αvβ3 Imaging in Patients with Breast Cancer and Neuroendocrine Neoplasms: Safety, Dosimetry and Tumor Imaging Ability
Clausen, Malene Martini, Carlsen, E. A., Christensen, C., Madsen, J., Brandt-Larsen, M., Klausen, Thomas Levin, Holm, S., Loft, A., Berthelsen, A. K., Kroman, Niels Thorndahl, Knigge, Ulrich & Kjær, Andreas, 2022, In: Diagnostics. 12, 4, 15 p., 851.Research output: Contribution to journal › Journal article › Research › peer-review
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First-line treatment of patients with disseminated poorly differentiated neuroendocrine carcinomas with carboplatin, etoposide, and vincristine: a single institution experience
Olsen, I. H., Langer, S. W., Jepsen, I., Assens, M., Federspiel, B., Hasselby, J. P., Hansen, C. P., Kjær, Andreas & Knigge, Ulrich, 2012, In: Acta Oncologica. 51, 1, p. 97-100 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional imaging of neuroendocrine tumors: a head-to-head comparison of somatostatin receptor scintigraphy, 123I-MIBG scintigraphy, and 18F-FDG PET
Binderup, Tina, Knigge, Ulrich, Loft, A., Mortensen, Jann, Pfeifer, A., Federspiel, B., Hansen, C. P., Højgaard, Liselotte, Kjær, Andreas, Binderup, T., Knigge, Ulrich, Jakobsen, A. L., Mortensen, Jann, Pfeifer, A., Federspiel, B. H., Hansen, C. P., Højgaard, Liselotte & Kjær, Andreas, 1 May 2010, In: Journal of Nuclear Medicine. 51, 5, p. 704-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastroenteropancreatic (GEP) Mixed Neuroendocrine-Non-Endocrine Neoplasms (MiNEN)
Laenkholm, I. T., Langer, Seppo W., Andreassen, Mikkel, Holmager, P., Hansen, C. P., Kjær, Andreas, Federspiel, B. & Knigge, Ulrich, 2019, p. 244-244. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Gastrointestinal Surgery of Neuroendocrine Neoplasms
Hansen, C. P., Olsen, I. M. H. & Knigge, Ulrich, 2015, Neuroendocrine Tumors: A Multidisciplinary Approach. Vol. 44. p. 149-63 15 p. (Frontiers of Hormone Research).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Gene Expression of Glucose Transporter 1 (GLUT1), Hexokinase 1 and Hexokinase 2 in Gastroenteropancreatic Neuroendocrine Tumors: Correlation with F-18-fluorodeoxyglucose Positron Emission Tomography and Cellular Proliferation
Binderup, Tina, Knigge, Ulrich, Federspiel, B. H., Sommer, P., Hasselby, Jane Preuss, Loft Jakobsen, A. & Kjær, Andreas, Dec 2013, In: Diagnostics. 3, 4, p. 372-84 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Goblet cell carcinoids: characteristics of a Danish cohort of 83 patients
Olsen, I. H., Holt, N., Langer, Seppo W., Hasselby, J. P., Grønbæk, H., Hillingsø, Jens Georg, Mahmoud, M., Ladekarl, M., Iversen, L. H., Kjær, Andreas, Federspiel, B. H. & Knigge, Ulrich, 2015, In: P L o S One. 10, 2, p. 1-17 17 p., e0117627.Research output: Contribution to journal › Journal article › Research › peer-review
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H3 receptor modulation of neuroendocrine responses to histamine and stress
Knigge, Ulrich, Kjær, Andreas, Jørgensen, H. & Warberg, J., 1998, The Histamine H3 Receptor. Elsevier, p. 41-58Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Head-to-head comparison of 64Cu-DOTATATE and 68Ga-DOTATOC PET/CT: a prospective study of 59 patients with neuroendocrine tumors
Johnbeck, C. B., Knigge, Ulrich, Loft, A., Berthelsen, A. K., Mortensen, Jann, Oturai, P., Langer, Seppo W., Elema, D. & Kjær, Andreas, Mar 2017, In: The Journal of Nuclear Medicine. 58, 3, p. 451-457 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histamine and prostaglandin interaction in regulation of oxytocin and vasopressin secretion
Knigge, Ulrich, Kjær, Andreas, Kristoffersen, U., Madsen, K., Miranda, C. L. T., Jørgensen, H. & Warberg, J., 2003, In: Journal of Neuroendocrinology. 15, p. 940-945Research output: Contribution to journal › Journal article › Research › peer-review
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Histamine and the regulation of body weight.
Jørgensen, E. A., Knigge, Ulrich, Warberg, J. & Kjær, Andreas, 2007, In: Neuroendocrinology. 86, 3, p. 210-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histamine stimulates c-fos expression in hypothalamic vasopressin-, oxytocin-, and corticotropin-releasing hormone-containing neurons
Kjær, Andreas, Larsen, P. J., Knigge, Ulrich, Møller, Morten & Warberg, J., Jan 1994, In: Endocrinology. 134, 1, p. 482-491 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histamine- and stress-induced prolactin secretion: Importance of vasopressin V1- and V2-receptors
Kjær, Andreas, Knigge, Ulrich & Warberg, J., 1994, In: European Journal of Endocrinology. 131, 4, p. 391-397 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histaminergic and catecholaminergic interactions in the central regulation of vasopressin and oxytocin secretion
Knigge, Ulrich, Willems, E. I., Jørgensen, H., Kjær, Andreas & Warberg, J., 1999, In: Endokrinologiya. 140, p. 3713-3719Research output: Contribution to journal › Journal article › Research › peer-review
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Histaminergic neurons are involved in the orexigenic effect of Orexin-A
Jørgensen, E. A., Knigge, Ulrich, Watanabe, T., Warberg, J. & Kjær, Andreas, 2006, In: Neuroendocrinology. 82, p. 70-77Research output: Contribution to journal › Journal article › Research › peer-review
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Hitherto unseen survival in an ALK-positive-patient with advanced stage adult ganglioneuroblastoma treated with personalized medicine
Risum, S., Knigge, Ulrich & Langer, Seppo W., Dec 2017, In: Clinical Case Reports. 5, 12, p. 2085-2087 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis
Ye, Y-X., Calcagno, C., Binderup, T., Courties, G., Keliher, E. J., Wojtkiewicz, G. R., Iwamoto, Y., Tang, J., Pérez-Medina, C., Mani, V., Ishino, S., Johnbeck, C. B., Knigge, U., Fayad, Z. A., Libby, P., Weissleder, R., Tawakol, A., Dubey, S., Belanger, A. P., Di Carli, M. F. & 4 others, , 2015, In: Circulation Research. 117, 10, p. 835-45 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Imaging surveillance in multiple endocrine neoplasia type 1: Ten years of experience with somatostatin receptor positron emission tomography
Said, M., Krogh, Jesper, Feldt-Rasmussen, Ulla, Rasmussen, Å. K., zwp671, zwp671, Rossing, Caroline Maria, Johannesen, Helle Hjorth, Oturai, P., Holmager, P., Kjær, Andreas, Klose, M., Langer, Seppo W., Knigge, Ulrich & Andreassen, Mikkel, 2023, In: Journal of Neuroendocrinology. 35, 8, e13322.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunohistochemical Profiles in 81 Patients with Resected Insulinomas
Andreassen, Mikkel, Ilett, E., Slater, E. P., Wiese, D., Hansen, C. P., Gehrke, N., Langer, Seppo W., Kjær, Andreas, Maurer, E., Federspiel, B., Bartsch, D. K. & Knigge, Ulrich, 2018, p. 136-136. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Impressive Response to TANDEM Peptide Receptor Radionuclide Therapy with 177Lu/225AcDOTA-LM3 Somatostatin Receptor Antagonist in a Patient with Therapy-Refractory, Rapidly Progressive Neuroendocrine Neoplasm of the Pancreas
Perrone, E., Ghai, K., Eismant, A., Andreassen, Mikkel, Langer, Seppo W., Knigge, Ulrich, Kjær, Andreas & Baum, R. P., 2024, In: Diagnostics. 14, 9, 7 p., 907.Research output: Contribution to journal › Journal article › Research › peer-review
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Incidence and Clinicopathological Features of Colorectal Neuroendocrine Carcinomas and Mixed Neuroendocrine-Nonneuroendocrine Neoplasms
Chiranth, D. J., Willemoe, G. L., Garbyal, Rajendra Singh, Melchior, L. C., Knigge, Ulrich, Langer, Seppo W. & Federspiel, B., 2019, In: Neuroendocrinology. 108, S1, p. 103-103 1 p., E01.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Incidence, clinical presentation and trends in indication for diagnostic work-up of small intestinal and pancreatic neuroendocrine tumors
Stensbøl, A. B., Krogh, Jesper, Holmager, P., Klose, M., Oturai, P., Kjær, Andreas, Hansen, C. P., Federspiel, B., Langer, Seppo W., Knigge, Ulrich & Andreassen, Mikkel, 2021, In: Diagnostics. 11, 11, 2030.Research output: Contribution to journal › Journal article › Research › peer-review
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Incidens, patologi og klinik ved neuroendokrine gastrointestinale tumorer
Federspiel, B. H., Hansen, C. P., Vainer, B., Hasselby, Jane Preuss, Bardram, L. & Knigge, Ulrich, 25 Oct 2010, In: Ugeskrift for Laeger. 172, 43, p. 2946-50 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increase of Ki-67 index and influence on mortality in patients with neuroendocrine neoplasms
Holmager, P., Langer, Seppo W., Federspiel, B., Willemoe, G. L., Garbyal, Rajendra Singh, Melchior, L., Klose, M., Kjær, Andreas, Hansen, C. P., Andreassen, Mikkel & Knigge, Ulrich, 2021, In: Journal of Neuroendocrinology. 33, 9, 8 p., e13018.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased susceptibility to diet-induced obesity in histamine-deficient mice
Jørgensen, E. A., Vogelsang, T. W., Knigge, Ulrich, Watanabe, T., Warberg, J. & Kjær, Andreas, 2006, In: Neuroendocrinology. 83, 5-6, p. 289-94 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Induction of Anti-Tumor Immune Responses by Peptide Receptor Radionuclide Therapy with 177Lu-DOTATATE in a Murine Model of a Human Neuroendocrine Tumor
Wu, Y., Pfeifer, A. K., Myschetzky, R. S. M., Garbyal, Rajendra Singh, Rasmussen, P., Knigge, Ulrich, Kristensen, M. H. & Kjær, Andreas, 2013, In: Diagnostics. 3, 4, p. 344-355 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Naloxone on the cellular immune response to head-up tilt in humans
Klokker, M., Secher, N. H., Madsen, P., Olesen, H. L., Matzen, S., Knigge, Ulrich, Warberg, J. & Pedersen, B. K., 1997, In: European Journal of Applied Physiology. 76, p. 415-420Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin/hypoglycemia-induced adrenocorticotropin and β-endorphin release: Involvement of hypothalamic histaminergic neurons
Kjær, Andreas, Knigge, Ulrich, Madsen, E. L., Soe-Jensen, P., Bach, F. W. & Warberg, J., May 1993, In: Endocrinology. 132, 5, p. 2213-2220 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions of histaminergic and serotonergic neurons in the hypothalamic regulation of prolactin and ACTH secretion
Jørgensen, H., Knigge, Ulrich, Kjær, Andreas & Warberg, J., 1996, In: Neuroendocrinology. 64, 5, p. 329-336 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-γ inhibits ghrelin expression and secretion via a somatostatin-mediated mechanism
Strickertsson, J. A. B., Døssing, K. B. V., Aabakke, A. J., Nilsson, H., Hansen, T. V. O., Knigge, Ulrich, Kjær, Andreas, Wadström, T. & Friis-Hansen, L., 2011, In: World Journal of Gastroenterology. 17, 26, p. 3117-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interventional treatment of neuroendocrine liver metastases
Knigge, Ulrich, Hansen, C. P. & Stadil, F., 2008, In: Surgeon. 6, 4, p. 232-239 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intravenous versus Oral Etoposide: Efficacy and Correlation to Clinical Outcome in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms (WHO G3)
Ali, A. A., Gronberg, M., Hjortland, G. O., Grønbæk, H., Ladekarl, M., Langer, Seppo W., Welin, S., Vestermark, L. W., Osterlund, P., Knigge, Ulrich, Sorbye, H. & Janson, E. T., 2018, p. 184-184. 1 p.Research output: Contribution to conference › Poster › Research › peer-review
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Intravenous versus oral etoposide: efficacy and correlation to clinical outcome in patients with high-grade metastatic gastroenteropancreatic neuroendocrine neoplasms (WHO G3)
Ali, A. S., Grönberg, M., Langer, Seppo W., Ladekarl, M., Hjortland, G. O., Vestermark, L. W., Österlund, P., Welin, S., Grønbæk, H., Knigge, Ulrich, Sorbye, H. & Janson, E. T., 2018, In: Medical Oncology. 35, 4, p. 1-7 7 p., 47.Research output: Contribution to journal › Journal article › Research › peer-review
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Involvement of histamine in suckling-induced release of oxytocin, prolactin and adrenocorticotropin in lactating rats
Schagen, F. H. E., Knigge, Ulrich, Kjær, Andreas, Larsen, P. J. & Warberg, J., 1996, In: Neuroendocrinology. 63, 6, p. 550-558 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Involvement of vasopressin v1- and v2-receptors in histamine-and stress-induced secretion of ACTH and β-endorphin
Kjær, Andreas, Knigge, Ulrich, Vilhardt, H., Bach, F. W. & Warberg, J., 1993, In: Neuroendocrinology. 57, 3, p. 503-509 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Karcinoide tumorer og gobletcelle-karcinoide tumorer i appendix
Knigge, Ulrich & Hansen, C. P., 31 May 2010, In: Ugeskrift for Laeger. 172, 22, p. 1678-81 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lokalisationsdiagnostik af neuroendokrine gastrointestinale tumorer
Kjær, Andreas, Knigge, Ulrich, Mortensen, Jann, Hansen, C. P. & Fallentin, E., 25 Oct 2010, In: Ugeskrift for Laeger. 172, 43, p. 2953-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-term outcomes after video-assisted thoracoscopic surgery in pulmonary large-cell neuroendocrine carcinoma
Soldath, Patrick, Binderup, Tina, Carstensen, F., Clausen, Malene Martini, Kjær, Andreas, Federspiel, B., Knigge, Ulrich, Langer, Seppo W. & Petersen, René Horsleben, 2022, In: Surgical Oncology. 41, 101728.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-term survival and recurrence after resection of bronchopulmonary carcinoids: A single-center cohort study of 236 patients
Soldath, Patrick, Binderup, Tina, Kjær, Andreas, Federspiel, B., Langer, Seppo W., Knigge, Ulrich & Petersen, René Horsleben, 2021, In: Lung Cancer. 156, p. 109-116 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lung and thymic carcinoids: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆
Baudin, E. & ESMO Guidelines Committee, E. G. C., 2021, In: Annals of Oncology. 32, 4, p. 439-451 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple endocrine neoplasia type 1 (MEN-1) and neuroendocrine neoplasms (NENs)
Effraimidis, G., Knigge, Ulrich, Rossing, M., Oturai, P., Rasmussen, Å. K. & Feldt-Rasmussen, Ulla, 2022, In: Seminars in Cancer Biology. 79, p. 141-162Research output: Contribution to journal › Review › Research › peer-review
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Neuroendocrine Carcinomas of the Gastroenteropancreatic System: A Comprehensive Review
Ilett, E. E., Langer, Seppo W., Olsen, I. H., Federspiel, B., Kjær, Andreas & Knigge, Ulrich, 2015, In: Diagnostics. 5, 2, p. 119-76 58 p.Research output: Contribution to journal › Review › Research › peer-review
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Neuroendocrine gastro-entero-pancreatic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Öberg, K., Knigge, Ulrich, Kwekkeboom, D., Perren, A. & ESMO Guidelines Working Group, E. G. W. G., 2012, In: Annals of Oncology. 23 Suppl 7, p. vii124-30Research output: Contribution to journal › Journal article › Research › peer-review
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Neuroendocrine neoplasms of the appendix: Characterization of 335 patients referred to the Copenhagen NET Center of Excellence
Holmager, P., Willemoe, G. L., Nielsen, K., Grøndahl, V., Klose, M., Andreassen, Mikkel, Langer, Seppo W., Hansen, C. P., Kjær, Andreas, Federspiel, B. H. & Knigge, Ulrich, 2021, In: European Journal of Surgical Oncology. 47, 6, p. 1357-1363 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neuronal histamine and expression of corticotropin-releasing hormone, vasopressin and oxytocin in the hypothalamus: Relative importance of H1 and H2 receptors
Kjær, Andreas, Larsen, P. J., Knigge, Ulrich, Jørgensen, H. & Warberg, J., 1998, In: European Journal of Endocrinology. 139, 2, p. 238-243Research output: Contribution to journal › Journal article › Research › peer-review
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Next Generation Sequencing of 294 Neuroendocrine G3 and Mixed Neuroendocrine and Non-Neuroendocrine Neoplasms Identifies Molecular Profile Linked to the Site of the Primary and Tumor Composition
Melchior, L. C., Willemoe, G. L., Garbyal, Rajendra Singh, Langer, Seppo W., Knigge, Ulrich & Federspiel, B., 2019, In: Neuroendocrinology. 108, Suppl. 1, p. 31-31 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Nordic 2023 guidelines for the diagnosis and treatment of lung neuroendocrine neoplasms
Dam, G., Grønbæk, H., Sundlöv, A., Botling, J., Sundin, A., Petersen, René Horsleben, Welin, S., Evensen, E., Sorbye, H., Tabaksblat, E., Arveschoug, A. K., Mortensen, Jann, Kjær, Andreas, Knigge, Ulrich, Tiensuu Janson, E. & Langer, Seppo W., 16 May 2023, In: Acta Oncologica. 62, 5, p. 431-437 7 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 916819
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Down-regulation of miR-129-5p and the let-7 family in neuroendocrine tumors and metastases leads to up-regulation of their targets Egr1, G3bp1, Hmga2 and Bach1
Research output: Contribution to journal › Journal article › Research › peer-review
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PET tracers for somatostatin receptor imaging of neuroendocrine tumors: current status and review of the literature
Research output: Contribution to journal › Review › Research › peer-review
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Somatostatin analogue treatment primarily induce miRNA expression changes and up-regulates growth inhibitory miR-7 and miR-148a in neuroendocrine cells
Research output: Contribution to journal › Journal article › Research › peer-review
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