Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor

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    176 - 200 out of 206Page size: 25
    1. 2005
    2. Published

      Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells

      Larsen, L., Størling, Joachim, Darville, M., Eizirik, D. L., Bonny, C., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Dec 2005, In: Diabetologia. 48, 12, p. 2582-90 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia

      Nolsøe, R. L., Kelly, J. A., Pociot, Flemming, Moser, K., Kristiansen, O. P., Mandrup-Poulsen, Thomas & Harley, J. B., 1 Dec 2005, In: Genes and Immunity. 6, 8, p. 699-706 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt

      Størling, Joachim, Binzer, J., Andersson, A., Züllig, R. A., Tonnesen, M., Knudsen, R. L. P., Spinas, G. A., Sandler, S., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Oct 2005, In: Diabetologia. 48, 10, p. 2039-50 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      An immune origin of type 2 diabetes?

      Kolb, H. & Mandrup-Poulsen, Thomas, 1 Jun 2005, In: Diabetologia. 48, 6, p. 1038-50 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes

      Hamid, Y. H., Rose, C. S., Urhammer, S. A., Glümer, C., Nolsøe, R., Kristiansen, O. P., Mandrup-Poulsen, Thomas, Borch-Johnsen, K., Jorgensen, T., Hansen, Torben & Pedersen, O., 1 Feb 2005, In: Diabetologia. 48, 2, p. 251-60 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.

      Størling, J., Zaitsev, S. V., Kapelioukh, I. L., Karlsen, A. E., Billestrup, N., Berggren, P. & Mandrup-Poulsen, Thomas, 2005, In: Endocrinology. 146, 7, p. 3026-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.

      Cardozo, A. K., Ortis, F., Storling, J., Feng, Y., Rasschaert, J., Tonnesen, M., Van Eylen, F., Mandrup-Poulsen, Thomas, Herchuelz, A. & Eizirik, D. L., 2005, In: Diabetes. 54, 2, p. 452-61 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Er der dokumentation for Lyrica til behandling af smertende diabetisk neuropati?

      Persson, F., Mogensen, C. E. & Mandrup-Poulsen, Thomas, 2005, In: Ugeskrift for læger. 167, 16, p. 1768-9; author reply 1769-70

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      European Nicotinamide Diabetes Intervention Trial (ENDIT)--sekundaerpublikation. En randomiseret, placebokontrolleret undersøgelse af intervention før debut af type 1-diabetes.

      Reimers, J. I., Larsen, C. M., Mandrup-Poulsen, Thomas & European Nicotinamide Diabetes Intervention Trial Group, E. N. D. I. T. G., 2005, In: Ugeskrift for læger. 167, 3, p. 293-6 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Interleukin-6 and diabetes: the good, the bad, or the indifferent?

      Kristiansen, O. P. & Mandrup-Poulsen, Thomas, 2005, In: Diabetes. 54 Suppl 2, p. S114-24

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Is puberty an accelerator of type 1 diabetes in IL6-174CC females?

      Gillespie, K. M., Nolsøe, R., Betin, V. M., Kristiansen, O. P., Bingley, P. J., Mandrup-Poulsen, Thomas & Gale, E. A. M., 2005, In: Diabetes. 54, 4, p. 1245-8 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Poor pregnancy outcome in women with type 2 diabetes

      Clausen, Tine Dalsgaard, Mathiesen, E., Ekbom, P., Hellmuth, E., Mandrup-Poulsen, Thomas & Damm, Peter, 2005, In: Diabetes Care. 28, 2, p. 323-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. 2004
    15. Published

      Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways

      Karlsen, A. E., Heding, P. E., Frobøse, H., Rønn, S. G., Kruhøffer, M., Orntoft, T. F., Darville, M., Eizirik, D. L., Pociot, Flemming, Nerup, J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 1 Nov 2004, In: Diabetologia. 47, 11, p. 1998-2011 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity

      Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity

      Kristiansen, O. P., Karlsen, A. E., Larsen, Z. M., Johannesen, Jesper, Pociot, Flemming, Mandrup-Poulsen, Thomas & Danish IDDM Epidemiology and Genetics Group and Danish Study Group of IDDM in Childhood, D. I. E. A. G. G. A. D. S. G. O. I. I. C., 1 Jun 2004, In: Scandinavian Journal of Immunology. 59, 6, p. 582-91 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Transplantation mellem enaeggede tvillinger

      Mandrup-Poulsen, Thomas, 26 Jan 2004, In: Ugeskrift for Laeger. 166, 5, p. 398-9; author reply 399

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Antitumorigenic effect of proteasome inhibitors on insulinoma cells.

      Størling, J., Allaman-Pillet, N., Karlsen, A. E., Billestrup, N., Bonny, C. & Mandrup-Poulsen, Thomas, 2004, In: Endocrinology. 146, 4, p. 1718-26 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.

      Maedler, K., Størling, J., Sturis, J., Zuellig, R. A., Spinas, G. A., Arkhammar, P. O. G., Mandrup-Poulsen, Thomas & Donath, M. Y., 2004, In: Diabetes. 53, 7, p. 1706-13 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Type 1 database mellitus: an inflammatory disease of the islet.

      Bergholdt, R., Heding, P., Nielsen, K., Nolsøe, R., Sparre, T., Størling, J., Nerup, J., Pociot, Flemming & Mandrup-Poulsen, Thomas, 2004, In: Advances in Experimental Medicine and Biology. 552, p. 129-53 24 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. 2003
    23. Published

      Association of a functional 17beta-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females

      Kristiansen, O. P., Nolsøe, R. L., Larsen, L., Gjesing, A. M. P., Johannesen, J., Larsen, Z. M. E., Lykkesfeldt, A. E., Karlsen, A. E., Pociot, Flemming, Mandrup-Poulsen, Thomas & DIEGG, D., 15 May 2003, In: Human Molecular Genetics. 12, 10, p. 1101-10 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. 1996
    25. Published

      Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine

      Andersen, H. U., Mauricio, D., Karlsen, A. E., Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, Feb 1996, In: European Journal of Endocrinology. 134, 2, p. 251-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 1988
    27. Published

      The bimodal effect of interleukin 1 on rat pancreatic beta-cells--stimulation followed by inhibition--depends upon dose, duration of exposure, and ambient glucose concentration

      Spinas, G. A., Palmer, J. P., Mandrup-Poulsen, Thomas, Andersen, Heine, Nerup, J. & Nielsen, Jens Høiriis, Oct 1988, In: Acta Endocrinologica. 119, 2, p. 307-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Effect of interleukin-1 on the biosynthesis of proinsulin and insulin in isolated rat pancreatic islets

      Hansen, B. S., Linde, S., Spinas, G. A., Welinder, B. S., Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, 1988, In: Biomedica Biochimica Acta. 47, 4-5, p. 305-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. 1987
    30. Published

      Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans

      Spinas, G. A., Hansen, B. S., Linde, S., Kastern, W., Mølvig, J., Mandrup-Poulsen, Thomas, Dinarello, C. A., Nerup, J. & Nielsen, Jens Høiriis, Jul 1987, In: Diabetologia. 30, 7, p. 474-80 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

      Mandrup-Poulsen, Thomas, Spinas, G. A., Prowse, S. J., Hansen, B. S., Jørgensen, D. W., Bendtzen, K., Nerup, J. & Nielsen, Jens Høiriis, May 1987, In: Diabetes. 36, 5, p. 641-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 923693