Thomas Jespersen
Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3, Building: 12-5-08
2200 København N
Denmark
Member of:
- Published
Usefulness of left atrial strain for predicting incident atrial fibrillation and ischaemic stroke in the general population
Alhakak, Alia Saed, Biering-Sørensen, S. R., Møgelvang, R., Modin, D., Jensen, G. B., Schnohr, P., Iversen, A. Z., Svendsen, Jesper Hastrup, Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: European heart journal. Cardiovascular Imaging. 23, 3, p. 363-371 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AMP-activated protein kinase downregulates Kv7.1 cell surface expression
Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein
Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Kv1.4 potassium channels by PKC and AMPK kinases
Andersen, M. N., Skibsbye, L., Saljic, Arnela, Larsen, M. Z., Rasmussen, Hanne Borger & Jespersen, Thomas, 20 Dec 2018, In: Channels (Austin). 12, 1, p. 34-44Research output: Contribution to journal › Journal article › Research › peer-review
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PKC and AMPK regulation of Kv1.5 potassium channels
Andersen, M. N., Skibsbye, L., Tang, C., Petersen, F., MacAulay, Nanna, Rasmussen, Hanne Borger & Jespersen, Thomas, 2015, In: Channels (Austin). 9, 3, p. 121-8 8 p.Research output: Contribution to journal › Letter › Research › peer-review
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Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes
Andreasen, Laura Korsholm, Ahlberg, G., Tang, C., Andreasen, C., Hartmann, J. P., Tfelt-Hansen, Jacob, Behr, E. R., Pehrson, S., Haunsø, Stig, LuCamp, Weeke, P. E., Jespersen, Thomas, Olesen, Morten Steen Salling & Svendsen, Jesper Hastrup, 2018, In: European Journal of Human Genetics. 26, p. 660–668Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.
Angelo, K., Jespersen, Thomas, Grunnet, Morten, Nielsen, Morten Schak, Klærke, Dan Arne & Olesen, Søren-Peter, 2002, In: Biophysical Journal. 83, 4, p. 1997-2006 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors
Bahrami, S., Jespersen, T., Pedersen, F. S., Duch, M. R. & Jespersen, Thomas, 2 Oct 2003, In: Gene. 315, p. 51-61 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Researchers in cardiology – Why and how to get on Twitter?
Benjamin Fyenbo, D., Charlotte Frederiksen, T., Dr Linz, Dominik Karl, Jespersen, Thomas, Dobrev, D., Gislason, Gunnar Hilmar, Betz, K., Saljic, Arnela & Nielsen Holck, E., 2022, In: IJC Heart and Vasculature. 40, 101010.Research output: Contribution to journal › Review › Research › peer-review
- Published
[68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction
Bentsen, Simon, Clemmensen, Andreas Høeg, Loft, Mathias Hougaard, Flethøj, M., Debes, Karina Poulsdóttir, Ludvigsen, Trine Pagh, Larsen, C. B., Kirchhoff, J., Olsen, Lisbeth Høier, Møller, J. E., Andersen, Thomas Lund, Johannesen, Helle Hjorth, Jespersen, Thomas & Kjær, Andreas, 2021, In: Diagnostics. 11, 10, 1807.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury
Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish
Berchtold, Martin Werner, Zacharias, T., Kulej, K., Wang, K., Torggler, R., Jespersen, Thomas, Chen, J. N., Larsen, M. R. & la Cour, J. M., 2016, In: Journal of Biological Chemistry. 291, 52, p. 26636-26646 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons
Boddum, K., Hougaard, C., Xiao-Ying Lin, J., von Schoubye, N. L., Jensen, H. S., Grunnet, M. & Jespersen, Thomas, 2017, In: Neuropharmacology. 118, p. 102-112 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy
Boddum, K., Saljic, Arnela, Jespersen, Thomas & Christensen, A. H., 2018, In: Cardiology. 140, 1, p. 8-13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.
Bondebjerg, J., Grunnet, Morten, Jespersen, Thomas & Meldal, Morten Peter, 2003, In: ChemBioChem. 4, 2-3, p. 186-94 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early systolic lengthening in patients with ST-segment elevation myocardial infarction: a novel predictor of cardiovascular events
Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2019, In: European Heart Journal. 40, Suppl. 1, p. 718-718 1 p., 1270 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Early Systolic Lengthening in Patients With ST-Segment-Elevation Myocardial Infarction: A Novel Predictor of Cardiovascular Events
Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Holm, A. E., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2020, In: Journal of the American Heart Association. 9, 3, p. e013835Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters
Buhl, Rikke, Carstensen, Helena, Hesselkilde, E. Z., Klein, B. Z., Hougaard, K. M., Ravn, K. B., Loft-Andersen, A. V., Fenner, Merle Friederike, Pipper, C. & Jespersen, Thomas, 2018, In: Journal of Veterinary Internal Medicine. 32, 4, p. 1410-1419 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of atrial fibrillation with implantable loop recorders in horses
Buhl, Rikke, Hesselkilde, E. M., Carstensen, Helena, Fenner, Merle Friederike, Jespersen, Thomas, Tfelt-Hansen, Jacob & Sattler, Stefan M, 2021, In: Equine Veterinary Journal. 53, 2, p. 397-403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implantable loop recorders can detect paroxysmal atrial fibrillation in Standardbred racehorses with intermittent poor performance
Buhl, Rikke, Nissen, Sarah Dalgas, Winther, M. L. K., Poulsen, S. K., Hopster-Iversen, Charlotte, Jespersen, Thomas, Sanders, P., Carstensen, Helena & Hesselkilde, E. M., 2021, In: Equine Veterinary Journal. 53, 5, p. 955-963Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle
Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.
Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses
Carstensen, Helena, Hesselkilde, E. Z., Fenner, Merle Friederike, Loft-Andersen, A. V., Flethøj, M., Kanters, Jørgen K., Sattler, Stefan M, Tfelt-Hansen, Jacob, Pehrson, S., Jespersen, Thomas & Buhl, Rikke, 2018, In: Journal of Veterinary Internal Medicine. 32, 5, p. 1708-1717 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses
Carstensen, Helena, Kjær, L., Haugaard, M. M., Flethøj, M., Hesselkilde, E. Z., Kanters, Jørgen K., Pehrson, S., Buhl, Rikke & Jespersen, Thomas, Jan 2018, In: Journal of Cardiovascular Pharmacology. 71, 1, p. 26-35 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation
Carstensen, Helena, Hesselkilde, E. Z., Haugaard, M. M., Flethøj, M., Carlson, J., Pehrson, S., Jespersen, Thomas, Platonov, P. G. & Buhl, Rikke, 2019, In: Journal of Cardiovascular Electrophysiology. 30, 4, p. 596-606Research output: Contribution to journal › Journal article › Research › peer-review
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Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses
Carstensen, Helena, Nissen, Sarah Dalgas, Saljic, Arnela, Hesselkilde, E. M., van Hunnik, A., Hohl, M., Sattler, Stefan M, Fløgstad, C., Hopster-Iversen, Charlotte, Verheule, S., Böhm, M., Schotten, U., Jespersen, Thomas & Buhl, Rikke, 2023, In: Journal of Cardiovascular Translational Research. 16, p. 1205–1219Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction
Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Antiarrhythmic effect of IKr activation in a cellular model of LQT3
Diness, Jonas Goldin, Hansen, R. S., Nissen, J. D., Jespersen, Thomas & Grunnet, Morten, 2008, In: Heart Rhythm. 6, 1, p. 100-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition
Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiarrhythmic effect of either negative modulation or blockade of small conductance Ca2+ activated K+ channels on ventricular fibrillation in guinea pig Langendorff perfused heart
Diness, J. G., Kirchhoff, J. E., Sheykhzade, Majid, Jespersen, Thomas & Grunnet, M., 8 May 2015, In: Journal of Cardiovascular Pharmacology. 66, 3, p. 294–299 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation
Diness, Jonas Goldin, Sørensen, U. S., Nissen, J. D., Al-Shahib, B., Jespersen, T., Grunnet, Morten, Hansen, R. S. & Jespersen, Thomas, Aug 2010, In: Circulation. Arrhythmia and electrophysiology. 3, 4, p. 380-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Myocardial performance index by tissue Doppler echocardiography predicts adverse events in patients with atrial fibrillation
Dons, M., Olsen, F. J., de Knegt, M. C., Fritz-Hansen, T., Mogelvang, R., Alhakak, A. S., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, May 2020, In: European Heart Journal Cardiovascular Imaging. 21, 5, p. 560-566Research output: Contribution to journal › Journal article › Research › peer-review
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Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs
Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.Research output: Contribution to journal › Journal article › Research › peer-review
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Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity
Drivsholm, A., Lund, Morten Asp Vonsild, Hedley, P. L., Jespersen, Thomas, Christiansen, M., Hansen, Torben & Holm, Jens-Christian, 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 12, p. 1351-1358Research output: Contribution to journal › Journal article › Research › peer-review
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Functional testing of a bicistronic retroviral vector for intracellular peptide production
Duch, M. R., Tolstrup, A., Dalum, I., Jespersen, Thomas, Mouritsen, S. & Pedersen, F. S., 1 Jun 1999, In: BioTechniques. 26, 6, p. 1032-4, 1036Research output: Contribution to journal › Journal article › Research › peer-review
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Transgene stability for three replication-competent murine leukemia virus vectors
Duch, M. R., Carrasco, M. L., Jespersen, T., Hansen, B. D., Pedersen, F. S. & Jespersen, Thomas, 31 Mar 2004, In: Gene. 329, p. 61-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo
Duch, M. R., Carrasco, M. L., Jespersen, T., Aagaard, L., Pedersen, F. S. & Jespersen, Thomas, 1 Jan 2004, In: Nucleic Acids Symposium Series. 32, 6, p. 2039-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype.
Dunø, M., Colding-Jørgensen, E., Grunnet, Morten, Jespersen, Thomas, Vissing, John & Schwartz, M., 2004, In: European Journal of Human Genetics. 12, 9, p. 738-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.
Dupuis, D. S., Schrøder, R. L., Jespersen, Thomas, Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, Søren-Peter, 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Left atrial functional measurements’ utility in predicting long-term risk of atrial fibrillation after isolated CABG
Dyhr, M. R., Olsen, F. J., Lindberg, S., Modin, D., Fritz-Hansen, T., Pedersen, S., Iversen, A., Galatius, S., Jespersen, Thomas, Møgelvang, R. & Biering-Sørensen, Tor, 2023, In: Echocardiography. 40, 7, p. 695-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)
Fenner, Merle Friederike, Carstensen, Helena, Nissen, Sarah Dalgas, Hesselkilde, E. Z., Lunddahl, C., Jensen, M. A. H., Loft-Andersen, A. V., Sattler, Stefan M, Platonov, P. G., El-Haou, S., Jackson, C., Tang, R., Kirby, R., Ford, J. W., Schotten, U., Milnes, J. T., Sørensen, U. S., Jespersen, Thomas & Buhl, Rikke, 2020, In: British Journal of Pharmacology. 177, 16, p. 3778-3794Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Small-Conductance Calcium-Activated Potassium Current (IK,Ca) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation
Fenner, Merle Friederike, Gatta, G., Sattler, Stefan M, Kuiper, M., Hesselkilde, E. M., Adler, Ditte Marie Top, Smerup, Morten Holdgaard, Schotten, U., Sørensen, U., Diness, J. G., Jespersen, Thomas, Verheule, S., Van Hunnik, A. & Buhl, Rikke, 2021, In: Frontiers in Physiology. 12, 614483.Research output: Contribution to journal › Journal article › Research › peer-review
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Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction
Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications
Gawalko, M., Agbaedeng, T. A., Saljic, Arnela, Mueller, D. N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, Thomas, Schotten, U., Crijns, H. J. G. M., Kalman, J. M., Sanders, P., Nattel, S., Dobrev, D. & Dr Linz, Dominik Karl, 2022, In: Cardiovascular Research. 118, 11, p. 2415–2427Research output: Contribution to journal › Review › Research › peer-review
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The gut microbial-derived metabolite trimethylamine N-oxide: A missing link between lifestyle-components and atrial fibrillation?
Gawalko, M., Jespersen, Thomas, Dobrev, D. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 29, 3 p., 100581.Research output: Contribution to journal › Editorial › Research › peer-review
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Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance
Gawalko, M., Saljic, Arnela, Li, N., Abu-Taha, I., Jespersen, Thomas, Dr Linz, Dominik Karl, Nattel, S., Heijman, J., Fender, A. & Dobrev, D., 2023, In: Cardiovascular Research. 119, 3, p. 614–630 17 p.Research output: Contribution to journal › Review › Research › peer-review
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Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations
Glinge, C., Clauss, S., Boddum, K., Jabbari, R., Jabbari, J., Risgaard, B., Tomsits, P., Hildebrand, B., Kääb, S., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2017, In: PLOS ONE. 12, 2, 16 p., e0167969.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological modulation of SK3 channels
Grunnet, Morten, Jespersen, Thomas, Angelo, K., Frøkjær-Jensen, Christian, Klærke, Dan Arne, Olesen, Poul & Jensen, B. S., 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 879-887 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses
Research output: Contribution to journal › Journal article › Research › peer-review
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340
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
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Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
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