Thomas Andrew Qvistgaard Jepps
Associate Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3
2200 København N.
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Dynein coordinates β2-adrenoceptor-mediated relaxation in normotensive and hypertensive rat mesenteric arteries
van der Horst, Jennifer, Rognant, Salomé, Hellsten, Ylva, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Hypertension. 79, 10, p. 2214-2227 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels
van der Horst, Jennifer, Greenwood, I. A. & Jepps, Thomas Andrew Qvistgaard, 2020, In: Frontiers in Physiology. 11, 12 p., 727.Research output: Contribution to journal › Review › Research › peer-review
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Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional sympatholysis in mouse skeletal muscle involves sarcoplasmic reticulum swelling in arterial smooth muscle cells
van der Horst, Jennifer, Møller, S., Kjeldsen, Sasha Alexandra Sampson, Wojtaszewski, Jørgen F P, Hellsten, Ylva & Jepps, Thomas Andrew Qvistgaard, 2021, In: Physiological Reports. 9, 23, 10 p., e15133.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)
de Jong, I. E. M. & Jepps, Thomas Andrew Qvistgaard, Dec 2018, In: Physiological Reports. 6, 23, 10 p., e13920 .Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael J., 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.Research output: Contribution to journal › Journal article › Research › peer-review
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Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly
van der Horst, Jennifer, Manville, R. W., Hayes, K., Thomsen, M. B., Abbott, G. W. & Jepps, Thomas Andrew Qvistgaard, 2020, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 40, 5, p. 1207-1219 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats
Stott, J. B., Barrese, V., Jepps, Thomas Andrew Qvistgaard, Leighton, E. V. & Greenwood, I. A., Mar 2015, In: Hypertension. 65, 3, p. 676-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KV7 potassium channels: a new therapeutic target in smooth muscle disorders
Stott, J. B., Jepps, Thomas Andrew Qvistgaard & Greenwood, I. A., 12 Dec 2014, In: Drug Discovery Today. 19, 4, p. 413-424 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts
Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of an atrial septal defect on the progression of atrial tachypacing-induced atrial fibrillation in a Danish Landrace pig: A case report
Saljic, Arnela, Hertel, Julie Norup, Leonhardt, C., Nissen, Sarah Dalgas, Dobrev, D., Jepps, Thomas Andrew Qvistgaard, Jespersen, Thomas & Sattler, Stefan M, 2022, In: IJC Heart and Vasculature. 40, 3 p., 101054.Research output: Contribution to journal › Letter › Research › peer-review
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Acute, pro-contractile effects of prorenin on rat mesenteric arteries
Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.Research output: Contribution to journal › Journal article › Research › peer-review
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The microtubule network enables Src kinase interaction with the Na,K-ATPase to generate Ca2+ flashes in smooth muscle cells
Rognant, Salomé, Kravtsova, V. V., Bouzinova, E. V., Melnikova, E. V., Krivoi, I. I., Pierre, S. V., Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Matchkov, V. V., 2022, In: Frontiers in Physiology. 13, 14 p., 1007340.Research output: Contribution to journal › Journal article › Research › peer-review
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Contractile responses in intact and mucosa-denuded human ureter: a comparison with urinary bladder detrusor preparations
Roedel, M., Ravens, U., Kasper, M., Wirth, M. P., Jepps, Thomas Andrew Qvistgaard & Propping, S., 1 Aug 2018, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 391, 8, p. 773-782 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNQ5 Potassium Channel Activation Underlies Vasodilation by Tea
Redford, K. E., Rognant, Salomé, Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2021, In: Cellular Physiology and Biochemistry. 55, S3, p. 46-64 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression and function of the K+ channel KCNQ genes in human arteries
Ng, F. L., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Harhun, M. I., Yeung, S. Y., Wan, A., Reddy, M., Melville, D., Nardi, A., Khong, T. K. & Greenwood, I. A., Jan 2011, In: British Journal of Pharmacology. 162, 1, p. 42-53 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mesenteric artery smooth muscle cells from hypertensive rats have increased microtubule acetylation
Mozzicato, Anthony Michael, Bastrup, Joakim Armstrong, Sanchez-Alonso, J. L., van der Horst, Jennifer, Gorelik, J., Hägglund, Per Mårten & Jepps, Thomas Andrew Qvistgaard, 2024, In: The Biochemical journal. 481, 5, p. 387-403Research output: Contribution to journal › Journal article › Research › peer-review
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Medicinal plant rosemary relaxes blood vessels by activating vascular smooth muscle KCNQ channels
Manville, R. W., Baldwin, S. N., Eriksen, E. Ø., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2023, In: FASEB Journal. 37, 9, p. 1-15 e23125.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNQ5 activation by tannins mediates vasorelaxant effects of barks used in Native American botanical medicine
Manville, R. W., Redford, K. E., van der Horst, Jennifer, Hogenkamp, D. J., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2022, In: FASEB Journal. 36, 9, 15 p., e22457.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines
Manville, R. W., van der Horst, Jennifer, Redford, K. E., Katz, B. B., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21236-21245Research output: Contribution to journal › Journal article › Research › peer-review
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Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle
Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia
Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries
Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Downregulation of Kv7.4 channel activity in primary and secondary hypertension
Jepps, Thomas Andrew Qvistgaard, Chadha, P. S., Davis, A. J., Harhun, M. I., Cockerill, G. W., Olesen, S. P., Hansen, R. S. & Greenwood, I. A., 2 Aug 2011, In: Circulation. 124, 5, p. 602-11 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles
Jepps, Thomas Andrew Qvistgaard, Greenwood, I. A., Moffatt, J. D., Sanders, K. M. & Ohya, S., Jul 2009, In: A J P: Gastrointestinal and Liver Physiology (Online). 297, 1, p. G107-15Research output: Contribution to journal › Journal article › Research
ID: 51475012
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MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension
Research output: Contribution to journal › Journal article › Research › peer-review
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130
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Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)
Research output: Contribution to journal › Journal article › Research › peer-review
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93
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Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse
Research output: Contribution to journal › Journal article › Research › peer-review
Published