Expression and function of the K+ channel KCNQ genes in human arteries

Research output: Contribution to journalJournal articleResearchpeer-review

Fu Liang Ng, Alison J Davis, Thomas Andrew Jepps, Maksym I Harhun, Shuk Yin Yeung, Andrew Wan, Marcus Reddy, David Melville, Antonio Nardi, Teck K Khong, Iain A Greenwood

KCNQ-encoded voltage-gated potassium channels (K(v) 7) have recently been identified as important anti-constrictor elements in rodent blood vessels but the role of these channels and the effects of their modulation in human arteries remain unknown. Here, we have assessed KCNQ gene expression and function in human arteries ex vivo.
Original languageEnglish
JournalBritish Journal of Pharmacology
Volume162
Issue number1
Pages (from-to)42-53
Number of pages12
ISSN0007-1188
DOIs
Publication statusPublished - Jan 2011

    Research areas

  • Aged, Arteries, Female, Humans, Immunohistochemistry, KCNQ Potassium Channels, Male, Middle Aged, Polymerase Chain Reaction, RNA, Messenger

ID: 108539502