Rune Ehrenreich Kuhre
Assistant Professor
- 2017
- Published
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the relationship between glucose absorption and glucose‐stimulated secretion of GLP‐1, neurotensin, and PYY from different intestinal segments in the rat
Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Saltiel, M. Y., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 3 Dec 2017, In: Physiological Reports. 5, 23, 13 p., e13507.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice
Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Larsen, Olav, Jepsen, Sara Lind, Balk-Møller, E., Andersen, Daniel Bjørklund, Deacon, Carolyn F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, Reidar, Hartmann, Bolette, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: Molecular Metabolism. 11, p. 84-95 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine
Booz, V., Christiansen, Charlotte Bayer, Kuhre, Rune Ehrenreich, Saltiel, M. Y., Sociali, G., Schaltenberg, N., Fischer, A. W., Heeren, J., Zocchi, E., Holst, Jens Juul & Bruzzone, S., 2019, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 35, 8 p., e3102.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients
Vestergaard, E. T., Hjelholt, A. J., Kuhre, Rune Ehrenreich, Møller, N., Larraufie, P., Gribble, F. M., Reimann, F., Jessen, N., Holst, Jens Juul & Jørgensen, J. O. L., 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2581-2592Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents
Christiansen, Charlotte Bayer, Trammell, Sam, Albrechtsen, Nicolai Jacob Wewer, Schoonjans, K., Albrechtsen, Reidar, Gillum, M. P., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G574-G584 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine
Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: Journal of Visualized Experiments. 144, e58533.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuromedin U Does Not Act as a Decretin in Rats
Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No direct effect of SGLT2 activity on glucagon secretion
Kuhre, Rune Ehrenreich, Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, Nicolai Jacob Wewer, Andersen, Daniel Bjørklund, Aivazidis, A., Chen, L., Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, Jens Juul, 2019, In: Diabetologia. 62, 6, p. 1011-1023Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors
Modvig, Ida Marie, Kuhre, Rune Ehrenreich & Holst, Jens Juul, Apr 2019, In: Physiological Reports. 7, 8, 13 p., e14056.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Madsen, Thomas Daugbjerg, Hansen, L. H., Hintze, John, Ye, Z., Jebari, S., Andersen, Daniel Bjørklund, Joshi, Hiren Jitendra, Ju, T., Goetze, Jens P. , Martin, C., Rosenkilde, Mette, Holst, Jens Juul, Kuhre, Rune Ehrenreich, Goth, C. K., Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2020, In: Nature Communications. 11, 1, 13 p., 4033.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy
Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hansen, S. H., Trammell, Sam, Svenningsen, J. S., Rehfeld, Jens Frederik, Bojsen-Møller, K. N., Jørgensen, N. B., Holst, Jens Juul, Madsbad, Sten, Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1
Jepsen, Sara Lind, Vestergaard, E. T., Larraufie, P., Gribble, F. M., Reimann, F., Jorgensen, J. O. L., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 1, p. 266-275Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, , 2020, In: Molecular Metabolism. 42, 18 p., 101080.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5
Trammell, Sam, Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P. & Kuhre, Rune Ehrenreich, 2020, In: Molecules. 25, 14 p., 2371.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion
Xu, S. F. S., Andersen, Daniel Bjørklund, Izarzugaza, J. M. G., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2020, In: Acta Physiologica. 229, 3, 15 p., e13464.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery
Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine
Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans
Vestergaard, E. T., Zubanovic, N. B., Rittig, N., Møller, N., Kuhre, Rune Ehrenreich, Holst, Jens Juul, Rehfeld, Jens Frederik & Thomsen, H. H., 2021, In: Diabetes, Obesity and Metabolism. 23, 8, p. 1834-1842Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms
Modvig, Ida Marie, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Xu, S., Engelstoft, M. S., Egerod, Kristoffer Lihme, Schwartz, Thue W., Ørskov, Cathrine, Rosenkilde, Mette & Holst, Jens Juul, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, p. E874-E885 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do sodium-glucose transporter-2 inhibitors increase plasma glucagon by direct actions on the alpha-cell? - and does the increase matter for the associated increase in endogenous glucose production?
Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2021, In: Diabetes, Obesity and Metabolism. 23, 9, p. 2009-2019Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass
Jonsson, I., Bojsen-Moller, K. N., Kristiansen, V. B., Veedfald, Simon, Albrechtsen, Nicolai Jacob Wewer, Clausen, T. R., Kuhre, Rune Ehrenreich, Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Svane, M. S., 2021, In: Frontiers in Endocrinology. 12, 11 p., 681116.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion
Kuhre, Rune Ehrenreich, Modvig, Ida Marie, Jepsen, Sara Lind, Kizilkaya, Hüsün Sheyma, Bæch-Laursen, C., Smith, C. A., Reimann, F., Gribble, F. M., Rosenkilde, Mette & Holst, Jens Juul, 2021, In: Frontiers in Endocrinology. 12, 12 p., 690387.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals
Martinussen, C., Svane, M. S., Bojsen-Møller, K. N., Jensen, Christian Zinck, Kristiansen, V. B., Bookout, A. L., Jorgensen, S. B., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Madsbad, Sten & Kuhre, Rune Ehrenreich, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. p. E443-E452 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40730697
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390
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Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
303
downloads
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
286
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The biology of glucagon and the consequences of hyperglucagonemia
Research output: Contribution to journal › Journal article › Research › peer-review
Published