Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

Publication year:
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1 - 50 out of 64Page size: 50
  1. 2014
  2. Published

    Pancreatic effects of GLP-1

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 22 Dec 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication

  3. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

    Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes

    Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  6. Published

    Therapies for inter-relating diabetes and obesity - GLP-1 and obesity

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans

    Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery

    Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

    Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients

    Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial

    Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  12. Published

    The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract

    Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals

    Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model

    Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Incretin secretion: direct mechanisms

    Balk-Møller, E., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 12 Jun 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), p. 1-3 3 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication

  18. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Jun 2014, In: Diabetes. 63, suppl 1, p. A491 1 p., Abstract no 1915-P.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  20. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes

    Pietraszek, A., Gregersen, S., Pedersen, S. B., Holst, Jens Juul & Hermansen, K., 14 May 2014, In: European Journal of Clinical Nutrition. 68, p. 1022-28 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus

    Torekov, Signe Sørensen, Holst, Jens Juul & Ehlers, M. R., May 2014, In: Diabetes, Obesity and Metabolism. 16, 5, p. 451-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition

    Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study

    Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes

    Harder-Lauridsen, N. M., Krogh-Madsen, Rikke, Holst, Jens Juul, Plomgaard, P., Leick, L., Pedersen, Bente Klarlund & Fischer, C. P., 1 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 7, p. E769-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans

    Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk

    Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

    Vrieze, A., Out, C., Fuentes, S., Jonker, L., Reuling, I., Kootte, R. S., van Nood, E., Holleman, F., Knaapen, M., Romijn, J. A., Soeters, M. R., Blaak, E. E., Dallinga-Thie, G. M., Reijnders, D., Ackermans, M. T., Serlie, M. J., Knop, F. K., Holst, J. J., van der Ley, C., Kema, I. P. & 6 others, Zoetendal, E. G., de Vos, W. M., Hoekstra, J. B. L., Stroes, E. S., Groen, A. K. & Nieuwdorp, M., Apr 2014, In: Journal of Hepatology. 60, 4, p. 824-31 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

    Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8

    Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade

    Aulinger, B. A., Bedorf, A., Kutscherauer, G., de Heer, J., Holst, Jens Juul, Göke, B. & Schirra, J., Mar 2014, In: Diabetes. 63, 3, p. 1079-92 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes

    Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Insulin resistance alters islet morphology in nondiabetic humans

    Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The incretin effect does not differ in trained and untrained, young, healthy men

    Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose

    Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: a prospective randomized study

    Tamandl, D., Sahora, K., Prucker, J., Schmid, R., Holst, J., Miholic, J., Goetzinger, P., Gnant, M. & Holst, Jens Juul, Feb 2014, In: World Journal of Surgery. 38, 2, p. 465-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery

    Madsbad, Sten, Dirksen, C. & Holst, Jens Juul, Feb 2014, In: The Lancet Diabetes & Endocrinology. 2, 2, p. 152-64 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs

    Sigalet, D. L., de Heuvel, E., Wallace, L., Bulloch, E., Turner, J., Wales, P. W., Nation, P., Wizzard, P. R., Hartmann, Bolette, Assad, M. & Holst, Jens Juul, 10 Jan 2014, In: Regulatory Peptides. 188, p. 70-80 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity

    Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  44. Published

    Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study

    Hartvigsen, M. L., Gregersen, S., Lærke, H. N., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., Jan 2014, In: European Journal of Clinical Nutrition. 68, 1, p. 84-90 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance

    Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The authors reply

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  48. Published

    A 25-year-old woman with type 2 diabetes and liver disease

    Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women

    Mark, A. B., Poulsen, M. W., Andersen, S., Andersen, J. M., Bak, M. J., Ritz, C., Holst, Jens Juul, Nielsen, J., de Courten, B., Dragsted, Lars Ove & Bügel, Susanne Gjedsted, 2014, In: Diabetes Care. 37, 1, p. 88-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial

    Larsen, J. R., Vedtofte, L., Holst, Jens Juul, Oturai, P., Kjær, Andreas, Corell, C. U., Vilsbøll, T. & Fink-Jensen, Anders, 2014, In: B M J Open. 4, 3, p. 1-9 9 p., e004227.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass

    Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Serup, A. K. L., Albers, P. H., Hansen, D. L., Worm, D., Naver, L., Kristiansen, V. B., Wojtaszewski, Jørgen F P, Kiens, Bente, Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2014, In: Diabetes. 63, 5, p. 1725-1737 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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