Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Assessment of Islet Alphaand beta-cell function

    Madsbad, Sten & Holst, Jens Juul, 2019, Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease: A Focus on Early Phase Clinical Drug Development. Springer, p. 37-74 38 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  2. Published

    Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion

    Müssig, K., Staiger, H., Machicao, F., Kirchhoff, K., Guthoff, M., Schäfer, S. A., Kantartzis, K., Silbernagel, G., Stefan, N., Holst, Jens Juul, Gallwitz, B., Häring, H. & Fritsche, A., 2009, In: Diabetes. 58, 7, p. 1715-20 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state

    Wever, M. C. M., van Meer, F., Charbonnier, L., Crabtree, D. R., Buosi, W., Giannopoulou, A., Androutsos, O., Johnstone, A. M., Manios, Y., Meek, C. L., Holst, Jens Juul, Smeets, P. A. M. & Full4Health consortium, F. C., 2021, In: NeuroImage. 240, 11 p., 118374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis

    Sato, S., Dyar, K. A., Treebak, J. T., Jepsen, S. L., Ehrlich, A. M., Ashcroft, S. P., Trost, K., Kunzke, T., Prade, V. M., Small, L., Basse, A. L., Schönke, M., Chen, S., Samad, M., Baldi, P., Barrès, R., Walch, A., Moritz, T., Holst, J. J., Lutter, D. & 2 others, Zierath, Juleen R & Sassone-Corsi, P., 2022, In: Cell Metabolism. 34, 2, p. 329-345.e8 26 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance

    Jujić, A., Nilsson, P. M., Persson, M., Holst, Jens Juul, Torekov, Signe Sørensen, Lyssenko, V., Groop, L., Melander, O. & Magnusson, M., 27 Jan 2016, In: The Journal of clinical endocrinology and metabolism. 101, 4, p. 1372-1380 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Atrial natriuretic peptide-like immunoreactive material (ANP-L1) is released from the adrenal gland by splanchnic nerve stimulation

    Duntas, L., Bornstein, S. R., Scherbaum, W. & Holst, Jens Juul, 1994, In: Exp.Clin.Endocrinol.. 101, p. 371-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Attenuated processing of proglucagon and glucagon-like peptide- 1 in carboxypeptidase E-deficient mice

    Friis-Hansen, L., Lacourse, K. A., Samuelson, L. C. & Holst, Jens Juul, 2001, In: J. Endocrinol.. 169, p. 595-602

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Augmented GLP-1 Secretion as Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion

    Martinussen, C., Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, Aug 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3233–3244

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Automated detection of hypoglycemia-induced EEG changes recorded by subcutaneous electrodes in subjects with type 1 diabetes--the brain as a biosensor

    Juhl, C. B., Højlund, K., Elsborg, R., Poulsen, M. K., Selmar, P. E., Holst, Jens Juul, Christiansen, C. & Beck-Nielsen, H., 1 Apr 2010, In: Diabetes Research and Clinical Practice. 88, 1, p. 22-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Bariatric surgery-which procedure is the optimal choice?

    Madsbad, Sten & Holst, Jens Juul, 2019, In: Lancet. 393, 10178, p. 1263-1264

    Research output: Contribution to journalComment/debateResearch

  11. Published

    Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice

    Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors

    Brighton, C. A., Rievaj, J., Kuhre, Rune Ehrenreich, Glass, L. L., Schoonjans, K., Holst, Jens Juul, Gribble, F. M. & Reimann, F., 2015, In: Endocrinology. 156, 11, p. 3961-1370 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Bile Modulates Secretion of Incretins and Insulin: A Study of Human Extrahepatic Cholestasis

    Mezza, T., Moffa, S., Ferraro, P. M., Quero, G., Capece, U., Carfi, A., Cefalo, C. M. A., Cinti, F., Sorice, G. P., Impronta, F., Mari, A., Pontecorvi, A., Alfieri, S., Holst, Jens Juul & Giaccari, A., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 7, p. 2685-2694

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Bile acid mediated effects on gut integrity and performance of early-weaned piglets

    de Diego-Cabero, N., Mereu, A., Menoyo, D., Holst, Jens Juul & Ipharraguerre, I. R., 2015, In: B M C Veterinary Research. 11, 1, p. 1-8 8 p., 111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

    Christiansen, Charlotte Bayer, Trammell, Sam, Albrechtsen, Nicolai Jacob Wewer, Schoonjans, K., Albrechtsen, Reidar, Gillum, M. P., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G574-G584 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Bile acids induce glucagon-like peptide 2 secretion with limited effects on intestinal adaptation in early weaned pigs

    Ipharraguerre, I. R., Tedó, G., Menoyo, D., de Diego Cabero, N., Holst, Jens Juul, Nofrarías, M., Mereu, A. & Burrin, D. G., Dec 2013, In: Journal of Nutrition. 143, 12, p. 1899-905 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy

    Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hansen, S. H., Trammell, Sam, Svenningsen, J. S., Rehfeld, Jens Frederik, Bojsen-Møller, K. N., Jørgensen, N. B., Holst, Jens Juul, Madsbad, Sten, Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Biliopancreatic diversion with duodenal switch (BPD-DS) and single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) result in distinct post-prandial hormone profiles

    Pereira, S. S., Guimarães, M., Almeida, R., Pereira, A. M., Lobato, C. B., Hartmann, Bolette, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2019, In: International Journal of Obesity. 43, p. 2518-2527

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, 1993, In: Diabetes. 42, p. 658-661

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, May 1993, In: Diabetes. 42, 5, p. 658-61 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1

    Nauck, M. A., Walberg, J., Vethacke, A., El-Ouaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, B., Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 89-97 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide-1

    Nauck, M. A., Walberg, J., Vethacke, A., El-Quaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 2004, In: Regul. Pept.. 118, p. 89-97

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet

    Alzahrani, A. H. A., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: European Journal of Nutrition. 60, 8, p. 4473-4482 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Bombesin inhibits histamine release from the rat oxyntic mucosa by a somatostatin-dependent mechanism.

    Sandvik, A. K., Brenna, E., Sundan, A., Holst, Jens Juul & Waldum, H. L., 1997, In: Scandinavian Journal of Gastroenterology. 30, p. 427-432

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, B., Gottschalck, I. B., Jeppesen, P. B., Miholic, J. & Henriksen, D. B., 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-820 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

    Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

    Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Butyrate and hexanoate-enriched triglycerides increase postprandrial systemic butyrate and hexanoate in men with overweight/obesity: A double-blind placebo-controlled randomized crossover trial

    van Deuren, T., Smolders, L., Hartog, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Blaak, E. E. & Canfora, E. E., 2023, In: Frontiers in Nutrition. 9, 19 p., 1066950.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    C-cell hyperplasia accompanying thyroid diseases other than medullary carcinoma: an immunocytochemical study by means of antibodies to calcitonin and somatostatin

    Scopsi, L., di Palma, S., Ferrari, C., Holst, Jens Juul & Rehfeld, J. F., 1991, In: Modern Pathology. Vol 4, no.3, p. 297-304

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published

    Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland

    Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Calcitonin gene-related peptide: effect on contractile activity and luminal-cross-sectional area in isolated, perfused porcine ileum

    Rasmussen, T. N., Gregersen, H., Harling, H. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 27, p. 787-792

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?

    Guimarães, M., Pereira, S. S., Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2021, In: Obesity Surgery. 31, p. 2174-2179

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. E-pub ahead of print

    Canagliflozin or acarbose versus placebo to ameliorate post-bariatric hypoglycaemia - The HypoBar I randomized clinical trial protocol

    Lobato, C. B., wql596, wql596, Bojsen-Møller, Kirstine Nyvold, Martinussen, C., Veedfald, Simon, Holst, Jens Juul, Madsbad, Sten, Jørgensen, N. B. & Dirksen, Carsten Moro, 2024, (E-pub ahead of print) In: Diabetic Medicine. e15320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine

    Ørskov, Cathrine, Buhl, T., Rabenhøj, L., Kofod, H. & Holst, Jens Juul, 24 Apr 1989, In: F E B S Letters. 247, 2, p. 193-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure

    Halbirk, M., Nørrelund, H., Møller, N., Holst, Jens Juul, Schmitz, O., Nielsen, B. R. R., Nielsen-Kudsk, J. E., Nielsen, S. S., Nielsen, T. T., Eiskjaer, H., Bøtker, H. E. & Wiggers, H., 1 Mar 2010, In: American Journal of Physiology: Heart and Circulatory Physiology. 298, 3, p. H1096-H1102

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Cardiovascular effects of incretins - focus on glucagon-like peptide-1 receptor agonists

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Cardiovascular Research. p. 886–904 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

    Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, Niels, Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Case report: Somatostatin producing teratoma, causing rapidly alternating extreme hyperglycemia and hypoglycemia, and ovarian somatostatinoma

    Gregersen, G., Holst, Jens Juul, Trankjaer, A., Stadil, F. & Mogensen, A. M., 2002, In: Metabolism. 51, 9, p. 1180-1183 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Cecal infusion of butyrate increases intestinal cell proliferation in piglets

    Kien, C. L., Blauwiekel, R., Bunn, J. Y., Jetton, T. L., Frankel, W. L. & Holst, Jens Juul, 2007, In: Journal of Nutrition. 137, 4, p. 916-922 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.

    Holst, Jens Juul, Gromada, K. & Rorsman, P., 1998, In: Pflugers Arch.. 435, p. 583-594

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals

    Haahr, M. E., Hansen, D. L., Fisher, P. M., Svarer, C., Stenbæk, D. S., Madsen, K., Madsen, J., Holst, Jens Juul, Baaré, W. F. C., Højgaard, Liselotte, Almdal, T. & Knudsen, G. M., 8 Apr 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 14, p. 5884-5889 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Cephalic phase secretion of insulin and other enteropancreatic hormones in humans

    Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Cerebral effects of glucagon-like peptide-1 receptor blockade before and after Roux-en-Y gastric bypass surgery in obese women: A proof-of-concept resting-state functional MRI study

    van Duinkerken, E., Bernardes, G., van Bloemendaal, L., Veltman, D. J., Barkhof, F., Mograbi, D. C., Gerdes, V. E. A., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M., ten Kulve, J. & Ijzerman, R. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 415-424 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Cerebrovascular changes following administration of gammaglobulins against substance P or calcitonin gene related peptide in monkey with subarachnoid haemorrhage

    Shiokawa, Y., Holst, Jens Juul, Rasmussen, J. T. N., Schmidt, P. & Svendgaard, N., 1993, In: British J. of Neurosurgery. 7, p. 507-518

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects

    Jacobsen, S. H., Olesen, S. C., Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Worm, Dorte, Almdal, Thomas Peter, Naver, L. S., Hvolris, L. E., Rehfeld, Jens Frederik, Wulff, B. S., Clausen, T. R., Hansen, D. L., Holst, Jens Juul & Madsbad, Sten, 2012, In: Obesity Surgery. 22, 7, p. 1084-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides

    Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Changes in serum leptin do not correlate to total fat mass in patients with thyrotoxicosis

    Zimmermann-Belsing, T., Dreyer, M., Holst, Jens Juul & Feldt-Rasmussen, U., 1998, In: J. Endocrinol.. 49, p. 589-595

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Changes in the Homeostatic Appetite System After Weight Loss Reflect a Normalization Toward a Lower Body Weight

    DeBenedictis, J. N., Nymo, S., Ollestad, K. H., Boyesen, G. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Truby, H., Kulseng, B. & Martins, C., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 7, p. e2538-e2546 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Changes of cognition and regional cerebral activity during acute hypoglycemia in normal subjects: A H2 15O positron emission tomographic study

    Bie-Olsen, L. G., Kjaer, T. W., Pedersen-Bjergaard, Ulrik, Lonsdale, M. N., Holst, Jens Juul, Law, Ian & Thorsteinsson, B., Jun 2009, In: Journal of Neuroscience Research. 87, 8, p. 1922-1928 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Chap.10. Degradation of glucagons

    Holst, Jens Juul, 1991, Degradation of Bioactive Substances: Physiology and Pathophysiology. Boca Raton, Florida: CRC Press, p. 167-180

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  55. Published

    Characterization of GLP-1 effects on beta cell function after meal ingestion in humans

    Ahren, B., Holst, Jens Juul & Mari, A., 2003, In: Diabetes Care. 26, p. 2860-2864

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans

    Ahrén, B., Holst, Jens Juul & Mari, A., Oct 2003, In: Diabetes Care. Supplement. 26, 10, p. 2860-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection

    Ekholm, E., Shaat, N. & Holst, Jens Juul, Oct 2012, In: Acta Diabetologica. 49, 5, p. 349-54 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Characterization of immunoactive pancreastatin in porcine tissues

    Børglum, T. D., Holst, Jens Juul & Fahrenkrug, J., 1991, In: Scand. J. Clin. Lab. Invest.. 51, p. 681-691

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets

    van der Meer, Y., Gerrits, W. J. J., van den Bosch, M., Holst, Jens Juul, Moreto, M., Buurman, W. A., Kulik, W. & van Kempen, T. A. T. G., Dec 2012, In: Journal of Animal Science. 90 Suppl 4, p. 302-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass

    Nielsen, S., Svane, M. S., Kuhre, Rune Ehrenreich, Clausen, T. R., Kristiansen, V. B., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Childhood Obesity at the Crossroads of Science and Social Justice

    Ludwig, D. S. & Holst, Jens Juul, 2023, In: JAMA. 329, 22, p. 1909-1910

    Research output: Contribution to journalEditorialResearch

  63. Published

    Cholecystokinin inhibits gastrin secretion independent of paracrine somatostatin secretion in the pig

    Schmidt, P. T., Hansen, L., Hilsted, L. & Holst, Jens Juul, 2004, In: Scandinavian Journal of Gastroenterology. 39, p. 217-221

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Cholecystokinin inhibits gastrin secretion independently of paracrine somatostatin secretion in the pig

    Schmidt, P. T., Hansen, L., Hilsted, Linda & Holst, Jens Juul, Mar 2004, In: Scandinavian Journal of Gastroenterology. 39, 3, p. 217-21 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans.

    Schmidt, W. E., Schenk, S., Nustede, R., Rovati, L. C., Holst, Jens Juul, Fölsch, U. & Creutzfeldt, W., 1994, In: Today in Medicine. Gastroenterology. 107, p. 1610-1620

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs

    Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses

    Rohde, U., Sonne, D. P., Christensen, M., Hansen, M., Brønden, A., Toräng, S., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 May 2016, In: The Journal of clinical endocrinology and metabolism. 101, 5, p. 2076-2083

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Circadian rhythms of GIP and GLP1 in glucose-tolerant and in type 2 diabetic patients after biliopancreatic diversion

    Mingrone, G., Nolfe, G., Gissey, G. C., Iaconelli, A., Leccesi, L., Guidone, C., Nanni, G. & Holst, Jens Juul, 2009, In: Diabetologia. 52, 5, p. 873-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Circulating GRP and gastrin in fetal lambs in response to luminal infusion of fluids

    Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1997.

    Research output: Contribution to conferencePaperResearch

  70. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes

    Fotheringham, A. K., Bagger, J. I., Borg, D. J., McCarthy, D. A., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Forbes, J. M., 2020, In: Nutrients. 12, 10, 12 p., 2928.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans

    Muller, M., Hernandez, M. A. G., Goossens, G. H., Reijnders, D., Holst, Jens Juul, Jocken, J. W. E., van Eijk, H., Canfora, E. E. & Blaak, E. E., 2019, In: Scientific Reports. 9, 9 p., 12515.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Circulating galanin: origin, metabolism, and pharmacokinetics in anesthetized pigs

    Harling, H. & Holst, Jens Juul, 1992, In: Am. J. of Physiology. 262, p. E52-E57

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Circulating leptin and thyroid dysfunction.

    Zimmermann-Belsing, T., Brabant, G., Holst, Jens Juul & Feldt-Rasmussen, Ulla, 2003, In: European Journal of Endocrinology. 149, 4, p. 257-71 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Circulating levels of ghrelin and GLP-1 are inversely related during glucose ingestion

    Djurhuus, C. B., Hansen, T. K., Gravholt, C., Ørskov, L., Hosoda, H., Kangawa, K., Jørgensen, J. O. L., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 411-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Circulating levels of incretin hormones an amylin in the fasting state and after oral glucose in growth hormone (GH-)deficient patients before and after GH replacement. A placebo controlled study

    Jørgensen, J. O. L., Rosenfalck, A. M., Fisker, S., Nyholm, B., Fineman, M. S., Schmitz, O., Madsbad, S., Holst, Jens Juul & Christiansen, J. S., 2000, In: European Journal of Endocrinology. 143, p. 593-599

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients

    Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

    Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, A. C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P. P., Porksen, S., Holl, R., Beaufort, C. D., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L., Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I. & 11 others, Chiarelli, F., Holst, J. J., Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L. & Hvidøre Study Group, H. S. G., 2007, In: European Journal of Endocrinology. 156, 6, p. 663-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

    Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, Cathrine, Jansen-Olesen, I., Chiarelli, F., Holst, Jens Juul, Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B. & Hansen, L., Jun 2007, In: European Journal of Endocrinology. Supplement. 156, 6, p. 663-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Cocaine and amphetamine-regulated transcript (CART) is present in hypothalamic neuroendocrine neurons and is related to the hypothalamo-pituitary portal circuit

    Larsen, P. J., Seier, V., Fink-Jensen, A., Holst, Jens Juul, Warberg, J. & Vrang, N., 2003, In: Journal of Neuroendocrinology. 15, p. 219-226

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit

    Larsen, P. J., Seier, V., Fink-Jensen, Anders, Holst, Jens Juul, Warberg, J. & Vrang, N., Mar 2003, In: Journal of Neuroendocrinology. 15, 3, p. 219-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity

    Høi-Hansen, T., Pedersen-Bjergaard, Ulrik, Andersen, R. D., Kristensen, Peter Lommer, Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A., Holst, Jens Juul, Dela, Flemming, Boomsma, F. & Thorsteinsson, B., Dec 2009, In: Journal of the Renin-Angiotensin-Aldosterone System. 10, 4, p. 216-29 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity

    Høi-Hansen, T., Pedersen-Bjergaard, U., Andersen, R. D., Kristensen, P. L., Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A., Holst, J. J., Dela, F., Boomsma, F., Thorsteinsson, B., Høi-Hansen, T., Pedersen-Bjergaard, U., Andersen, R. D., Kristensen, P. L., Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A. & 4 others, Holst, J. J., Dela, F., Boomsma, F. & Thorsteinsson, B., 2009, In: Journal of the Renin-Angiotensin-Aldosterone System. 10, 4, p. 216-29 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Colesevelam has no acute effect on postprandial GLP-1 levels but abolishes gallbladder refilling

    Gether, I. M., Bahne, E., Nerild, H. H., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2024, In: European Journal of Endocrinology. 190, 4, p. 314-326 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1

    Shang, Q., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 298, 3, p. G419-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Colonic GLP-2 is not sufficient to promote jejunal adaptation in a PN-dependent rat model of human short bowel syndrome

    Koopmann, M. C., Liu, X., Boehler, C. J., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2009, In: Journal of Parenteral and Enteral Nutrition. 33, 6, p. 629-38; discussion 638-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.

    Piche, T., des Varannes, S. B., Sacher-Huvelin, S., Holst, Jens Juul, Cuber, J. C. & Galmiche, J. P., 2003, In: Gastroenterology. 124, 4, p. 894-902 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

    Canfora, E. E., van der Beek, C. M., Jocken, J. W. E., Goossens, G. H., Holst, Jens Juul, Olde Damink, S. W. M., Lenaerts, K., Dejong, C. H. C. & Blaak, E. E., 24 May 2017, In: Scientific Reports. 7, 12 p., 2360.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Colonic lactulose fermentation has no impact on glucagon-like peptide-1 and peptide-YY secretion in healthy young men

    Christiansen, Charlotte Bayer, Veedfald, Simon, Hartmann, Bolette, Gauguin, A. M., Møller, Søren, Moritz, Thomas, Madsbad, Sten & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. 77-87

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized controlled trial

    Sandsdal, Rasmus Michael, Juhl, C. R., Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Blond, Martin Bæk, Rosenkilde, M., Bogh, A. F., Gliemann, Lasse, Jensen, Jens-Erik Beck, Antoniades, C., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Cardiovascular Diabetology. 22, 1, 12 p., 41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Combinatorial, additive and dose-dependent drug–microbiome associations

    Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, Helft, G., Isnard, R., Ji, B., Kuhn, M., Le Chatelier, E., Myridakis, A., Olsson, L., Pons, N., Prifti, E., Quinquis, B., Roume, H., Lewinter, C., Søndertoft, N. B., Pedersen, H. K., Hansen, T. H., Hartmann, Bolette, Holst, Jens Juul, Hornbak, M., Jørgensen, Niklas Rye, Justesen, Johanne Marie, Krarup, N., Svendstrup, M. & The MetaCardis Consortium*, T. M. C., 2021, In: Nature. 600, p. 500-517 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized Single-Blinded Placebo Controlled Study

    Behary, P., Tharakan, G., Alexiadou, K., Johnson, N., Albrechtsen, N. J. W., Kenkre, J., Cuenco, J., Hope, D., Anyiam, O., Choudhury, S., Alessimii, H., Poddar, A., Minnion, J., Doyle, C., Frost, G., Le Roux, C., Purkayastha, S., Moorthy, K., Dhillo, W., Holst, J. J. & 4 others, Ahmed, A. R., Prevost, A. T., Bloom, S. R. & Tan, T. M., 2019, In: Diabetes Care. 42, 7, 8 p., dc190449.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists

    Hansen, L. S., wbf943, wbf943, Svendsen, B., Christensen, M., Hartmann, Bolette, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Sep 2015, In: Diabetologia. 58, 1 supplement, p. S276-S277 2 p., 569.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  94. Published

    Combining GLP-1 receptor agonists with insulin: therapeutic rationales and clinical findings

    Holst, Jens Juul & Vilsbøll, Tina, 2013, In: Diabetes, Obesity and Metabolism. 15, 1, p. 3-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses

    pjx571, pjx571, Mahendran, Y., Jonsson, Anna Elisabet, Gjesing, A. P., Weeke, P. E., Jørgensen, M. E., Færch, K., Witte, D. R., Holst, Jens Juul, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, drb459, drb459, Torekov, Signe Sørensen, Kanters, Jørgen K. & Hansen, Torben, 2018, In: B M C Genetics. 19, 1, p. 1-9 9 p., 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Comparable Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Basal Fuel Metabolism and Insulin Sensitivity in Individuals with Obesity and Type 2 Diabetes

    Brodersen, K., Nielsen, M. F., Richelsen, B., Lauritzen, E. S., Pahle, E., Abrahamsen, J., Hartmann, Bolette, Holst, Jens Juul & Møller, N., 2022, In: Journal of Diabetes Research. 2022, 9 p., 5476454.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice

    Small, Lewin Barkla, Ehrlich, Amy M, Iversen, Jo Frøkjær, Ashcroft, Stephen Paul, Trošt, K., Moritz, Thomas, Hartmann, Bolette, Holst, Jens Juul, Treebak, Jonas Thue, Zierath, Juleen R & Barrès, Romain, 2022, In: Molecular Metabolism. 57, 8 p., 101440.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Comparative effect of orally administered sodium butyrate before or after weaning on growth and several indices of gastrointestinal biology of piglets

    Le Gall, M., Gallois, M., Sève, B., Louveau, I., Holst, Jens Juul, Oswald, I. P., Lallès, J. & Guilloteau, P., 2009, In: British Journal of Nutrition. 102, 9, p. 1285-96 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published
  100. Published

    Comparison of Glycomacropeptide with Phenylalanine Free-Synthetic Amino Acids in Test Meals to PKU Patients: No Significant Differences in Biomarkers, Including Plasma Phe Levels

    Ahring, K. K., Lund, A. M., Jensen, E., Jensen, T. G., Brondum-Nielsen, K., Pedersen, M., Bardow, A., Holst, Jens Juul, Rehfeld, Jens Frederik & Moller, L. B., 2018, In: Journal of Nutrition and Metabolism. 2018, p. 1-11 6352919.

    Research output: Contribution to journalJournal articleResearchpeer-review

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