Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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β-Lactoglobulin Is Insulinotropic Compared with Casein and Whey Protein Ingestion during Catabolic Conditions in Men in a Double-Blinded Randomized Crossover Trial
Mose, M., Møller, N., Jessen, N., Mikkelsen, U. R., Christensen, B., Rakvaag, E., Hartmann, Bolette, Holst, Jens Juul, Jørgensen, J. O. L. & Rittig, N., 2021, In: Journal of Nutrition. 151, 6, p. 1462-1472 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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alpha-Glucosidase inhibition (acarbose) fails to enhance secretion of glucagon-like peptide 1 (7-36 amide) and to delay gastric emptying in Type 2 diabetic patients
Hücking, K., Kostic, Z., Pox, C., Ritzel, R., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., Apr 2005, In: Diabetic Medicine. 22, 4, p. 470-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, 2005, In: Metabolism - Clinical and Experimental. 54, 10, p. 1398-406 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect
Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal
Naessén, S., Carlström, K., Holst, Jens Juul, Hellström, P. M. & Hirschberg, A. L., 2011, In: American Journal of Clinical Nutrition. 94, 4, p. 967-972 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Will GLP-1 treatment increase blood pressure? Summary and comment
Holst, Jens Juul, 2003, In: Diabetes Monitor. 15, p. 15-17Research output: Contribution to journal › Journal article › Research › peer-review
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Why is it so difficult to measure glucagon-like peptide-1 in a mouse?
Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
Roager, H. M., Vogt, J. K., Kristensen, M. B., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., Gøbel, R. J., Landberg, R., Ross, A. B., Brix, S., Holck, J., Meyer, A. S., Sparholt, M. H., Christensen, A. F., Carvalho, V., Hartmann, B. & 18 others, , Jan 2019, In: Gut. 68, 1, p. 83-93 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Which to choose, an oral or an injectable glucagon-like peptide-1 receptor agonist?
Holst, Jens Juul, 2019, In: The Lancet. 394, 10192, p. 4-6Research output: Contribution to journal › Editorial › Research › peer-review
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Whey protein potentiates the intestinotrophic action of glucagon-like peptide-2 in parenterally fed rats
Liu, X., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2009, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 297, 5, p. R1554-62Research output: Contribution to journal › Journal article › Research › peer-review
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Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Moehlig, M. & Pfeiffer, A. F. H., 2006, In: British Journal of Nutrition. 96, 5, p. 795-798 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Möhlig, M. & Pfeiffer, A. F. H., Nov 2006, In: The British Journal of Nutrition. 96, 5, p. 795-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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What is Diabetes Remission?
Holst, Jens Juul & Madsbad, Sten, 2021, In: Diabetes Therapy. 12, p. 641-646 6 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Holst, Jens Juul, 2021, In: Cell Reports Medicine. 2, 5, 2 p., 100284.Research output: Contribution to journal › Comment/debate › Research
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What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell?
Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Holst, Jens Juul & Petersen, N., 2021, In: Frontiers in Endocrinology. 12, 19 p., 694284.Research output: Contribution to journal › Review › Research › peer-review
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Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function
Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial
Jensen, N. J., Wodschow, H. Z., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T., Rungby, Jørgen & Thomsen, M. N., 2022, In: Clinical Nutrition. 41, 7, p. 1605-1612 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss-induced improvements of endothelial function and cardiovascular risk factors are maintained with exercise, liraglutide or the combination
Lundgren, J. R., Bladbjerg, E. M., Janus, C., Gliemann, Lasse, Olsen, L. M., Juhl, C. R., Jensen, Simon Birk Kjær, Thirumathyam, R., Stallknecht, Bente Merete, Holst, Jens Juul, Hove, Jens Dahlgaard, Madsbad, Sten, Antoinades, C. & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S457-S457 1 p., 959.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial
Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine
Gerstenberg, M. K., Andersen, Daniel Bjørklund, Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, Bolette, Rehfeld, Jens Frederik, Petersen, N., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels
pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
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WITHDRAWN: Glucagon processing
Steiner, D. F., Albrechtsen, Nicolai Jacob Wewer, Rehfeld, Jens Frederik & Holst, Jens Juul, 2016, The Curated Reference Collection in Neuroscience and Biobehavioral Psychology. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Voices: Insulin and beyond
Roth, J., Ashcroft, F. M., Wollheim, C. B., Kieffer, T. J., Cherrington, A. D., Bergman, R. N., Taylor, R., Najjar, S. M., Pedersen, Oluf Borbye, Ellingsgaard, H., Holst, Jens Juul, Nauck, M. A., Kadowaki, T., Czech, M. P., Corvera, S., Saltiel, A. R., Corkey, B. E. & Atkinson, M. A., 2021, In: Cell Metabolism. 33, 4, p. 692-699 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes
Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., Aug 2005, In: The Journal of clinical endocrinology and metabolism. 90, 8, p. 4888-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vildagliptin, a dipeptidyl peptidase-IV inhibitor improves model-assessed beta-cell function in patients with type 2 diabetes
Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Duning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 4888-4894Research output: Contribution to journal › Journal article › Research
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Vasoactive intestinal peptide in the porcine adrenal gland
Ehrhart-Bornstein, M., Bornstein, S. R. & Holst, Jens Juul, 1991, In: Neuroendocrinology. 54, p. 623-628Research output: Contribution to journal › Journal article › Research › peer-review
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Vasoactive intestinal peptide (VIP) stimulates androstenedione release in isolated perfused pig adrenals
Bornstein, S. R., Ehrhart-Bornstein, M., Stromeyer, H. G., Adler, G., Scherbaum, W. A. & Holst, Jens Juul, 1993, In: Life Sciences. 52, p. 135-140Research output: Contribution to journal › Journal article › Research › peer-review
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Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine
Christensen, L. W., Kuhre, Rune Ehrenreich, Janus, C., Svendsen, B. & Holst, Jens Juul, 17 Sep 2015, In: Physiological Reports. 3, 9, p. 1-13 13 p., e122551.Research output: Contribution to journal › Journal article › Research › peer-review
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Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass
Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin-releasing peptide, and HCl from porcine non-antral stomach
Holst, Jens Juul, Skak-Nielsen, T., Ørskov, Cathrine & Seier-Poulsen, S., Aug 1992, In: Scandinavian Journal of Gastroenterology. 27, 8, p. 677-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin releasing peptide and HC1 from porcine non-antral stomach
Holst, Jens Juul, Skak-Nielsen, T., Ørskov, C. & Poulsen, S. S., 1992, In: Scandinavian Journal of Gastroenterology. 27, p. 677-685Research output: Contribution to journal › Journal article › Research › peer-review
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Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X. W., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-R1264Research output: Contribution to journal › Journal article › Research › peer-review
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Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., Nov 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-64Research output: Contribution to journal › Journal article › Research › peer-review
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Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action
Johannessen, H., Revesz, D., Kodama, Y., Cassie, N., Skibicka, K. P., Barrett, P., Dickson, S., Holst, Jens Juul, Rehfeld, Jens Frederik, van der Plasse, G., Adan, R., Kulseng, B., Ben-Menachem, E., Zhao, C. & Chen, D., Jan 2017, In: Obesity Surgery. 27, 1, p. 177-185 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice
Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.Research output: Contribution to journal › Journal article › Research › peer-review
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Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Schmidt, P. & Holst, Jens Juul, 1997, In: Peptides. 18, p. 373-379Research output: Contribution to journal › Journal article › Research › peer-review
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Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice
Windeløv, Johanne Agerlin, Pedersen, Jens & Holst, Jens Juul, Jun 2016, In: Physiological Reports. 4, 11, 6 p., e12824.Research output: Contribution to journal › Journal article › Research › peer-review
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Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia?
Hansen, A. M. K., Bödvarsdottir, T. B., Nordestgaard, D. N. E., Heller, Rasmus, Gotfredsen, C. F., Maedler, K., Fels, J., Holst, Jens Juul & Karlsen, A., 2011, In: Diabetologia. 54, 6, p. 1379-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Updates in weight loss surgery and gastrointestinal peptides
Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet
Madsen, S., Bak, S. Y., Yde, C. C., Jensen, H. M., Knudsen, T. A., Bæch-Laursen, C., Holst, Jens Juul, Laustsen, C. & Hedemann, M. S., 2023, In: Metabolites. 13, 9, 21 p., 974.Research output: Contribution to journal › Journal article › Research › peer-review
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Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report
Knop, Filip Krag, Lund, Asger Bach, Madsbad, Sten, Holst, Jens Juul, Krarup, T. & Vilsbøll, T., 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.Research output: Contribution to journal › Journal article › Research › peer-review
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Type 2 diabetes mellitus
DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, Jens Juul, Hu, F. B., Kahn, C. R., Raz, I., Shulmann, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015, In: Nature Reviews. Disease Primers. 1, 22 p., 15019.Research output: Contribution to journal › Journal article › Research › peer-review
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Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists
Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Sengupta, S., Kaufmann, A., Thomsen, S., Hartmann, B., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Færch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O. & 12 others, , 2023, medRxiv, 35 p.Research output: Working paper › Preprint › Research
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Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study
Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S. & Krarup, T. M., 1 Apr 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-33 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial
Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748Research output: Contribution to journal › Conference abstract in journal › Research
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Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
Holst, Jens Juul, Ørskov, Cathrine, Nielsen, Olaf & Schwartz, Thue W., 1987, In: F E B S Letters. 211, 2, p. 169-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man
Wettergren, A., Schjoldager, B., Mortensen, P. E., Myhre, J., Christiansen, J. & Holst, Jens Juul, 1993, In: Digestive Diseases and Sciences. Vol. 38, no. 4, p. 665-673Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss
Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with GLP-1 Receptor Agonists
Madsbad, Sten & Holst, Jens Juul, 2018, Diabetes: Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 45 p. (Endocrinology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Treatment of type 2 diabetes with glucagonlike peptide 1
Holst, Jens Juul, 1998, In: Current Opinion in Endocrin. and Diabetes. 5, p. 108-115Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists
Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, 2009, In: International Journal of Clinical Practice. 63, 8, p. 1154-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.
Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of short bowel patients with glucagon-like peptide-2 (GLP-2), a newly discovered intestinotrophic, anti-secretory, and transit modulating peptide
Jeppesen, P. B., Hartmann, B., Thulesen, J., Graff, J., Lohmann, J., Hansen, B. S., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul & Mortensen, P. B., 2001, In: Today in Medicine. Gastroenterology. 120, p. 806-815Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of insulin resistance and obesity by stimulating GLP-1 release
Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010Research output: Patent
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Treatment of adult short bowel syndrome patients with teduglutide
Nørholk, L. M., Holst, Jens Juul & Jeppesen, Palle Bekker, 2012, In: Expert Opinion on Pharmacotherapy. 13, 2, p. 235-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1
Holst, Jens Juul, Sep 1999, In: Expert Opinion on Investigational Drugs. 8, 9, p. 1409-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1
Holst, Jens Juul, 1999, In: Exp. Opin. Invest. Drugs. 8, p. 1409-1415Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture
Holst, Jens Juul, 2021, In: Diabetes. 70, 11, p. 2468-2475 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
Jensen, P. B., Blume, N., Mikkelsen, J. D., Larsen, P. J., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., 1998, In: J. Clin. Invest.. 101, p. 503-510Research output: Contribution to journal › Journal article › Research › peer-review
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Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia
Madsen, O. D., Karlsen, C., Blume, N., Jensen, H. I., Larsson, L. & Holst, Jens Juul, 1995, In: Scand. J. Clin. Lab. Invest.. 55, suppl. 220, p. 27-36Research output: Contribution to journal › Journal article › Research › peer-review
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Transmitters in the control of gastrin and acid secretion in the pig stomach
Holst, Jens Juul, Nørre Ramussen, T., Schmidt, P. & Poulsen, S. S., 1993, Gastrin. New York: Raven Press, p. 243-258Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain
Ugleholdt, Randi Kjærsgaard, Pedersen, Jens, Bassi, Maria Rosaria, Füchtbauer, E., Jørgensen, S. M., Kissow, Hannelouise, Nytofte, N., Poulsen, Steen Seier, Rosenkilde, Mette, Seino, Y., Thams, P., Holst, Peter Johannes & Holst, Jens Juul, Dec 2011, In: The Journal of Biological Chemistry. 286, 52, p. 44632-44645 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes
Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets
Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, Jens Juul, Reimann, F. & Gribble, F. M., Oct 2016, In: Diabetologia. 59, 10, p. 2156-2165 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells
Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tissue levels and postprandial secretion of the intestinal growth factor, GLP-2 in inflammatory bowels disease: comparison with PYY
Schmidt, P. T., Ljung, T., Hartmann, B., Hare, K. J., Holst, Jens Juul & Hëllstrøm, P. M., 2005, In: European Journal of Gastroenterology and Hepathology. 17, p. 207-212Research output: Contribution to journal › Journal article › Research
- Published
Tissue levels and post-prandial secretion of the intestinal growth factor, glucagon-like peptide-2, in controls and inflammatory bowel disease: comparison with peptide YY
Schmidt, P. T., Ljung, T., Hartmann, Bolette, Hare, K. J., Holst, Jens Juul & Hellström, P. M., Feb 2005, In: European journal of gastroenterology & hepatology. 17, 2, p. 207-12 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-dependent intestinal adaptation and GLP-2 alterations after small bowel resection in rats
Ljungmann, K., Hartmann, B., Kissmeyer-Nielsen, P. & Holst, Jens Juul, 2001, In: Am J Physiol-Gastr L. 281, p. G779-G785Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time of day differences in appetite and gut hormone responses to meal and stress challenges in adults with normal-weight and obesity
Carnell, S., Papantoni, A., Grillot, C. L., Ungredda, T., Ellis, S., Mehta, N., Holst, Jens Juul & Geliebter, A., 2022, In: Physiology & Behavior. 254, 14 p., 113890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects
Knop, Filip Krag, Konings, E., Timmers, S., Schrauwen, P., Holst, Jens Juul & Blaak, E. E., 11 May 2013, In: Diabetic Medicine. 30, 10, p. 1214-1218 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1.
Holst, Jens Juul, 2002, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 18, 6, p. 430-41 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Therapies for inter-relating diabetes and obesity - GLP-1 and obesity
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ¤use of glycaemic index tables to predict glycaemic index of composite breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Pedersen, D., Tetens, I., Holst, Jens Juul & Astrup, A., 2004, In: British Journal of Nutrition. 91, 6, p. 979-989 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The use of glycaemic index tables to predict glycaemic index of breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Tetens, Inge , Holst, Jens Juul & Astrup, A., 2005, In: British Journal of Nutrition. 94, 1, p. 135-136 2 p.Research output: Contribution to journal › Letter › Research › peer-review
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The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract
Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist.
Thulesen, J., Knudsen, L. B., Hartmann, B., Hastrup, S., Kissow, Hannelouise, Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2002, In: Regulatory Peptides. 103, 1, p. 9-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The successful transfer of insulin treated patients with diabetes due to Kir6.2 (KCNJ11) mutations to oral sulfonylureas
Pearson, E. R., Flechtner, I., Njølståd, P. R., Malecki, M. T., Flanagan, S., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J. J., Holst, Jens Juul, Clark, P. M., Ellard, S. E., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: N. Engl. J. Med.. 355, p. 467-477Research output: Contribution to journal › Journal article › Research
- Published
The structure of wheat bread influences the postprandial metabolic response in healthy men
Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., Oct 2015, In: Food & Function. 6, 10, p. 3236-48 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The spectrum of antidiabetic actions of GLP-1 in patients with diabetes
Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes
Lund, Asger Bach, Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 6, p. E1038-E1046 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the incretins in the postprandial bone remodelling
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice
Ørgaard, A. & Holst, Jens Juul, Sep 2017, In: Diabetologia. 60, 9, p. 1731-1739 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety - effect of obesity and weight reduction
Verdich, C., Toubro, S., Buemann, B. & Holst, Jens Juul, 2001, In: International Journal of Obesity. 25, p. 1206-1214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of incretins on insulin function and glucose homeostasis
Holst, Jens Juul, Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2021, In: Endocrinology. 162, 7, 10 p., bqab065.Research output: Contribution to journal › Review › Research › peer-review
- Published
The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.
Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of glucagon in the acute therapeutic effects of SGLT2 inhibition
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 12, p. 2619-2629 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of endogenous GIP and GLP-1 in postprandial bone homeostasis
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of empagliflozin-induced metabolic changes for cardiac function in patients with type 2 diabetes. A randomized cross-over magnetic resonance imaging study with insulin as comparator
Thirumathyam, R., Richter, Erik A., van Hall, Gerrit, Holst, Jens Juul, Fenger, M., Goetze, Jens P. , Dixen, Ulrik, Vejlstrup, N., Madsbad, Sten, Madsen, Per & Jørgensen, N. B., 2024, In: Cardiovascular Diabetology. 23, 1, p. 1-13 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes
Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Hansen, N. L., Stensen, S., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: European Journal of Endocrinology. 184, 3, p. 387-398 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies
Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391Research output: Contribution to journal › Review › Research › peer-review
- Published
The release of gastric inhibitory peptide, glucagon-like peptide-1, and insulin after oral glucose test in colectomized subjects.
Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The regulation of function, growth and survival of GLP-1-producing L-cells.
Kuhre, Rune Ehrenreich, Holst, Jens Juul & Kappe, C., 1 Jan 2016, In: Clinical Science. 130, 2, p. 79-91 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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