Christina Christoffersen

Christina Christoffersen

Associate Professor


  1. Published

    Vascular function in adults with cyanotic congenital heart disease

    Tarp, J. B., Clausen, P., Celermajer, D., Christoffersen, Christina, Jensen, A. S., Sorensen, K., Sillesen, Henrik, Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas, Feldt-Rasmussen, Bo & Søndergaard, Lars, 2020, In: IJC Heart and Vasculature. 30, 7 p., 100632.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH

    Kristiansen, M. N. B., Veidal, S. S., Christoffersen, Christina, Feigh, M., Vrang, N., Roth, J. D., Erickson, M., Adorini, L. & Jelsing, J., 2019, In: B M C Gastroenterology. 19, 1, 11 p., 228 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The signal peptide anchors apolipoprotein m in plasma lipoproteins and prevents rapid clearance of apolipoprotein m from plasma

    Christoffersen, Christina, Ahnstrom, J., Axler, O., Christensen, E. I., Dahlback, B. & Nielsen, L. B., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 6, p. E62-E63

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma

    Christoffersen, Christina, Ahnström, J., Axler, O., Christensen, E. I., Dahlbäck, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 27, p. 18765-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    The role of aetiology in cardiac manifestations of chronic kidney disease: the CPH-CKD ECHO study

    Christensen, J., Landler, N. E., Olsen, F. J., Sørensen, I. M. H., Bjergfelt, S. S., Ballegaard, E. L. F., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A. L., Christoffersen, Christina, Bro, S. & Biering-Sørensen, Tor, 2024, (E-pub ahead of print) In: International Journal of Cardiovascular Imaging.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles

    Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The metabolic signature of cardiovascular disease and arterial calcification in patients with chronic kidney disease

    Sørensen, I. M., Bisgaard, Line, Bjergfelt, S. S., Ballegaard, E. L., Biering-Sørensen, Tor, Landler, N. E., Pedersen, T. X., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Bro, S. & Christoffersen, Christina, 2022, In: Atherosclerosis. 350, p. 109-118 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosis

    Arkensteijn, B. W. C., Berbée, J. F. P., Rensen, P. C. N., Nielsen, L. B. & Christoffersen, Christina, 25 Feb 2013, In: International Journal of Molecular Sciences (Online). 14, 3, p. 4419-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The apoM/S1P Complex - A Mediator in Kidney Biology and Disease?

    Bisgaard, Line & Christoffersen, Christina, 2021, In: Frontiers in Medicine. 8, 11 p., 754490.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism

    Metz, Sophia, Krarup, N. T., Bryrup, T., Støy, J., Andersson, E. A., Christoffersen, Christina, Neville, M. J., Christiansen, Malene Revsbech, Jonsson, Anna Elisabet, Witte, D. R., Kampmann, U., Nielsen, L. B., Jørgensen, Niklas Rye, Karpe, F., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 2022, In: Journal of the Endocrine Society. 6, 5, 10 p., bvac034.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

    Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Super-Resolution Ultrasound Imaging of Renal Vascular Alterations in Zucker Diabetic Fatty Rats during the Development of Diabetic Kidney Disease

    Søgaard, S. B., Andersen, S. B., Taghavi, I., Schou, M., Christoffersen, Christina, Jacobsen, Jens Christian Brings, Kjer, H. M., Gundlach, C., McDermott, Amy, Jensen, J. A., Nielsen, Michael Bachmann & Sorensen, Charlotte Mehlin, 12 Oct 2023, In: Diagnostics. 13, 20, 3197.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Super-Resolution Ultrasound Imaging Provides Quantification of the Renal Cortical and Medullary Vasculature in Obese Zucker Rats: A Pilot Study

    Søgaard, S. B., Andersen, S. B., Taghavi, I., Hoyos, C. A. V., Christoffersen, Christina, Hansen, Kristoffer Lindskov, Jensen, J. A., Nielsen, Michael Bachmann & Sorensen, Charlotte Mehlin, Jul 2022, In: Diagnostics. 12, 7, 1626.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Subclinical atherosclerosis in patients with cyanotic congenital heart disease

    Tarp, J. B., Sorgaard, M. H., Christoffersen, Christina, Jensen, A. S., Sillesen, Henrik, Celermajer, D., Eriksson, P., Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas & Søndergaard, Lars, 2019, In: International Journal of Cardiology. 277, p. 97-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Study protocol: Long-term effect of the New Nordic Renal Diet on phosphorus and lipid homeostasis in patients with chronic kidney disease, stages 3 and 4: a randomised controlled trial

    Hansen, N. M., Rix, M., Kamper, A., Feldt-Rasmussen, Bo, Christoffersen, Christina, Astrup, A. & Salomo, L., 2021, In: B M J Open. 11, 8, 7 p., e045754.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43

    Morel, S., Christoffersen, Christina, Axelsen, L. N., Montecucco, F., Rochemont, V., Frias, M. A., Mach, F., James, R. W., Naus, C. C., Chanson, M., Lampe, P. D., Nielsen, Morten Schak, Nielsen, L. B. & Kwak, B. R., 13 Jan 2016, In: Cardiovascular Research. 109, p. 385-396 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

    Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, Clausen, Henrik, 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Regional distribution and severity of arterial calcification in patients with chronic kidney disease stages 1-5: a cross-sectional study of the Copenhagen chronic kidney disease cohort

    Sorensen, I. M. H., Saurbrey, S. A. K., Hjortkjaer, H. O., Brainin, P., Carlson, N., Ballegaard, E. L. F., Kamper, A., Christoffersen, Christina, Feldt-Rasmussen, Bo, Kofoed, Klaus Fuglsang & Bro, S., 2020, In: BMC Nephrology. 21, 1, 11 p., 534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure

    Chirinos, J. A., Zhao, L., Jia, Y., Frej, C., Adamo, L., Mann, D., Shewale, S. V., Millar, J. S., Rader, D. J., French, B., Brandimarto, J., Margulies, K. B., Parks, J. S., Wang, Z., Sieffert, D. A., Fang, J., Sweitzer, N., Christoffersen, C., Dahlbäck, B., Car, B. D. & 3 others, Gordon, D. A., Cappola, T. P. & Javaheri, A., 2020, In: Circulation. 141, 18, p. 1463–1476

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA

    Bosteen, M. H., Dahlbäck, B., Nielsen, L. B. & Christoffersen, Christina, 1 Mar 2015, In: Journal of Lipid Research. 56, 3, p. 754-759 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Plasma activin A rises with declining kidney function and is independently associated with mortality in patients with chronic kidney disease

    Nordholm, A., Sørensen, I. M. H., Bjergfelt, S. S., Fuchs, A., Kofoed, Klaus Fuglsang, Landler, N. E., Biering-Sørensen, Tor, Carlson, N., Feldt-Rasmussen, Bo, Christoffersen, Christina & Bro, S., 2023, In: Clinical Kidney Journal. 16, 12, p. 2712-2720 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Osteopontin deficiency dampens the pro-atherogenic effect of uraemia

    Pedersen, T. X., Madsen, M., Nielsen, N. M. J., Christoffersen, Christina, Vikeså, J., Bro, S., Hultgårdh-Nilsson, A. & Nielsen, L. B., 1 Jun 2013, In: Cardiovascular Research. 98, 3, p. 352-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats

    Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael J., 2021, In: Scientific Reports. 11, 1, 18 p., 12712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Opposing effects of apolipoprotein m on catabolism of apolipoprotein B-containing lipoproteins and atherosclerosis

    Christoffersen, Christina, Pedersen, T. X., Gordts, P. L. S. M., Roebroek, A. J. M., Dahlbäck, B. & Nielsen, L. B., 2010, In: Circulation Research. 106, 10, p. 1624-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis

    Gaudio, I. D., Hendrix, S., Christoffersen, Christina & Wadsack, C., 25 Jan 2020, In: International Journal of Molecular Sciences. 21, 3, 789.

    Research output: Contribution to journalJournal articleResearchpeer-review

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