Cathrine Ørskov

Cathrine Ørskov

Head of Department

ORCID: 0000-0002-7762-2372

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  1. Published

    Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

    Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Secretion of glucagon-like peptide-1 and reactive hypoglycemia after partial gastrectomy

    Andreasen, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Digestion. 55, p. 221-228

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae

    Antenucci, F., Fougeroux, Cyrielle Elyette, Deeney, A., Ørskov, Cathrine, Rycroft, A., Holst, Peter Johannes & Bojesen, Anders Miki, Jan 2018, In: Veterinary Research. 49, 1, 11 p., 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Gut-derived glucagon in man: [Meeting Abstract]

    Baekdal, M., Lund, A., Albrechtsen, Nicolai Jacob Wewer, Egholk, J., Jorsal, T., Black-Juel, C. T., Dal, Jenna Elizabeth Hunt, Galsgaard, Katrine Douglas, Rigbolt, K., Palnaes, C., Ørskov, Cathrine, Poulsen, Steen Seier, Holst, Jens Juul, Villsboll, T. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 472.

    Research output: Contribution to journal › Conference abstract in journal › Research

  5. Published

    IFNγ and perforin cooperate to control infection and prevent fatal pathology during persistent gammaherpesvirus infection in mice

    Bartholdy, C., Høgh-Petersen, M., Storm, P., Holst, Peter Johannes, Ørskov, Cathrine, Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 31 Mar 2014, In: Scandinavian Journal of Immunology. 79, 6, p. 395-403 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression

    Billeschou, Anna, Johansen, C. D., Christensen, J. B., Kjeldsen, Sasha Alexandra Sampson, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Serizawa, R., Hornum, Mads, Porrini, E., Pedersen, Jens, Ørskov, Cathrine, Gluud, Lise Lotte, Sorensen, Charlotte Mehlin, Holst, Jens Juul, Albrechtsen, Reidar & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Communications Biology . 5, 1, 13 p., 1278.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    MEK kinase 1 activity is required for definitive erythropoiesis in the mouse fetal liver.

    Bonnesen, B., Ørskov, Cathrine, Rasmussen, S., Holst, Peter Johannes, Christensen, Jan Pravsgaard, Eriksen, K. W., Qvortrup, Klaus, Odum, N. & Labuda, T., 2005, In: Blood. 106, 10, p. 3396-404 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Naturally occurring products of proglucagon 111-160 in the porcine and human small intestine

    Buhl, T., Thim, L., Kofod, H., Ørskov, Cathrine, Harling, H. & Holst, Jens Juul, 25 Jun 1988, In: Journal of Biological Chemistry. 263, 18, p. 8621-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients

    Creutzfeldt, W. O., Kleine, N., Willms, B., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., Jun 1996, In: Diabetes Care. Supplement. 19, 6, p. 580-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

    Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis

    Denninger, K., Rasmussen, S. B., Larsen, J. M., Ørskov, Cathrine, Poulsen, Steen Seier, Sørensen, P., Christensen, Jan Pravsgaard, Illges, H., Ødum, Niels & Labuda, T., 2011, In: American Journal of Pathology. 179, 4, p. 1884-93 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8

    Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice

    Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Glucagon receptor signaling is not required for N-carbamoyl glutamate- And L-citrulline-induced ureagenesis in mice

    Galsgaard, Katrine Douglas, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Winther-Sørensen, Marie, Stojanovska, E., Vilstrup, H., Ørskov, Cathrine, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 5, p. G912-G927

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

    Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice

    Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Antidiabetogenic Effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus

    Gutniak, M., Ørskov, Cathrine, Holst, Jens Juul, Ahrén, B. & Efendic, S., 1992, In: New England Journal of Medicine. 326, p. 1316-1322

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Role of Gastrin‐Releasing Peptide in Vagal Control of Gastrin Secretion

    Holst, Jens Juul, KNUHTSEN, S., Ørskov, Cathrine, SKAK‐NIELSEN, T., Poulsen, Steen Seier & NIELSEN, O. V., 1 Jan 1988, In: Annals of the New York Academy of Sciences. 547, 1, p. 514-515 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine

    Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In: Molecular Endocrinology. 140, 11, p. 5356-63 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Structure, measurement, and secretion of human glucagon-like peptide-2

    Hartmann, B., Johnsen, A. H., Ørskov, Cathrine, Adelhorst, K., Thim, L. & Holst, J. J., 2000, In: Peptides. 21 (1), p. 73-80

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor

    Hennen, S., Kodra, J. T., Soroka, V., Krogh, B. O., Wu, X., Kaastrup, P., Ørskov, Cathrine, Rønn, S. G., Schluckebier, G., Barbateskovic, S., Gandhi, P. S. & Reedtz-Runge, S., 2016, In: Scientific Reports. 6, 11 p., 26236.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Constitutive activity of glucagon receptor mutants

    Hjorth, S. A., Ørskov, Cathrine & Schwartz, Thue W., 1998, In: Molecular Endocrinology. 12, no. 1, p. 78-86

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    On the regulatory functions of neuropeptide Y (NPY) with respect to vascular resistance and exocrine and endocrine secretion in the pig pancreas

    Holst, Jens Juul, Ørskov, Cathrine, Knuhtsen, S., Sheikh, S. & Nielsen, O. V., Aug 1989, In: Acta Physiologica Scandinavica. 136, 4, p. 519-26 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Proglucagon processing in porcine and human pancreas

    Holst, Jens Juul, Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, Bolette & Ørskov, Cathrine, 1994, In: Journal of Biological Chemistry. 269, 29, p. 18827-33 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut

    Holst, Jens Juul, Ørskov, Cathrine, Nielsen, Olaf & Schwartz, Thue W., 1987, In: F E B S Letters. 211, 2, p. 169-74 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Incretin hormones--an update

    Holst, Jens Juul & Ørskov, Cathrine, 2001, In: Scandinavian Journal of Clinical & Laboratory Investigation. 234, p. 75-85 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects

    Holst, Jens Juul, Toft-Nielsen, M. B., Ørskov, Cathrine, Nauck, M. & Willms, B., 26 Dec 1996, In: Annals of the New York Academy of Sciences. 805, p. 729-36 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin-releasing peptide, and HCl from porcine non-antral stomach

    Holst, Jens Juul, Skak-Nielsen, T., Ørskov, Cathrine & Seier-Poulsen, S., Aug 1992, In: Scandinavian Journal of Gastroenterology. 27, 8, p. 677-85 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    GRP-producing nerves control antral somatostatin and gastrin secretion in pigs

    Holst, Jens Juul, Ørskov, Cathrine & Poulsen, Steen Seier, Dec 1987, In: American Journal of Physiology (Consolidated). 253, 6 Pt 1, p. G767-74

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Somatostatin is an essential paracrine link in acid inhibition of gastrin secretion

    Holst, Jens Juul, Ørskov, Cathrine & Poulsen, S. S., 1992, In: Digestion. 51, p. 95-102

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.

    Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  35. Published

    Quality of the transgene-specific CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination

    Holst, Peter Johannes, Ørskov, Cathrine, Thomsen, Allan Randrup & Christensen, Jan Pravsgaard, 2010, In: Journal of Immunology. 184, 8, p. 4431-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Secretion of neurotensin from isolated perfused porcine ileum

    Holst Pedersen, J., Knuthsen, S., Bernabei, M., Ørskov, Cathrine & Holst, Jens Juul, May 1988, In: Regulatory Peptides. 21, 1-2, p. 13-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, Jan 1994, In: Metabolism. 43, 1, p. 104-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Effect of glucagon-like peptide-1 (proglucagon 78 - 107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    GLP-1-induced renal vasodilation in rodents depends exclusively on the known GLP-1 receptor and is lost in pre-hypertensive rats

    Jensen, E. P., Møller, S., Hviid, A. V. R., Veedfald, Simon, Holst, Jens Juul, Pedersen, Jens, Ørskov, Cathrine & Sorensen, Charlotte Mehlin, 2020, In: American Journal of Physiology: Renal Physiology. 318, 6, p. F1409-F1417

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    A processing enzyme cleaving avian progastrin at post-Phe bonds

    Jensen, H., Ørskov, Cathrine, Rehfeld, Jens Frederik & Johnsen, A. H., 5 May 2001, In: B B A - Reviews on Cancer. 1547, 1, p. 64-71 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

    Jepsen, Sara Lind, Grunddal, Kaare Villum, Albrechtsen, Nicolai Jacob Wewer, Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, Cathrine, Poulsen, Steen Seier, Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, Carolyn F., Schwartz, Thue W., Christ, A. D., Martin, R. E. & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E1081-E1093

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N. & 3 others, Jelsing, J., Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6403–6416 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    No direct effect of SGLT2 activity on glucagon secretion

    Kuhre, Rune Ehrenreich, Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, Nicolai Jacob Wewer, Andersen, Daniel Bjørklund, Aivazidis, A., Chen, L., Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, Jens Juul, 2019, In: Diabetologia. 62, 6, p. 1011-1023

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Pancreas and gut hormone responses to oral glucose and intravenous glucagon in cystic fibrosis patients with normal, impaired and diabetic glucose tolerance

    Laang, S., Thorsteinsson, B., Røder, M. E., Ørskov, Cathrine, Holst, Jens Juul, Nerup, J. & Koch, C., 1993, In: Acta Endoctrinologica. 128, p. 207-214

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem

    Larsen, P. J., Tang-Christensen, M., Holst, Jens Juul & Ørskov, Cathrine, 1997, In: Neuroscience. Vol. 77, No. 1, p. 257-270

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

    Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

    Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms

    Modvig, Ida Marie, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Xu, S., Engelstoft, M. S., Egerod, Kristoffer Lihme, Schwartz, Thue W., Ørskov, Cathrine, Rosenkilde, Mette & Holst, Jens Juul, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, p. E874-E885 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Colocalization of GLP-1 and GIP in human and porcine intestine

    Mortensen, K., Petersen, L. L. & Ørskov, Cathrine, 2000, In: Annals of the New York Academy of Sciences. 921, p. 469-72 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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