Thomas Mandrup-Poulsen
Professor
- 2014
- Published
Altering β-cell number through stable alteration of miR-21 and miR-34a expression
Backe, M. B., Novotny, G. W., Christensen, D. P., Grunnet, L. G. & Mandrup-Poulsen, Thomas, 26 Feb 2014, In: Islets. 6, 1, p. 1-8 8 p., e27754.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale prospective T cell function assays in shipped, unfrozen blood samples: experiences from the multicenter TRIGR trial
Hadley, D., Cheung, R. K., Becker, D. J., Girgis, R., Palmer, J. P., Cuthbertson, D., Krischer, J. P., Dosch, H., TRIGR North America Investigators, T. N. A. I. & Mandrup-Poulsen, Thomas, Feb 2014, In: Clinical and Vaccine Immunology (Online). 21, 2, p. 203-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, , 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist
Klementiev, B., Li, S., Korshunova, Irina, Dmytriyeva, O., Pankratova, Stanislava, Walmod, P. S., Kjær, L. K., Dahllöf, M. S., Lundh, M., Christensen, D. P., Mandrup-Poulsen, Thomas, Bock, E. & Berezin, V., 2014, In: Journal of Neuroinflammation. 11, 1, p. 27Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J Mice
Fjære, E., Aune, U. L., Røen, K., Keenan, A. H., Ma, Tao, Borkowski, K., Kristensen, D. M. B., Novotny, G. W., Mandrup-Poulsen, Thomas, Hudson, B. D., Milligan, G., Xi, Y., Newman, J. W., Haj, F. G., Liaset, B., Kristiansen, Karsten & Madsen, L., 2014, In: The Journal of Biological Chemistry. 289, 23, p. 16032-16045 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis
Prause, Michala Cecilie Burstein, Christensen, D. P., Billestrup, Nils & Mandrup-Poulsen, Thomas, 2014, In: PLOS ONE. 9, 1, p. 1-11 11 p., e87067.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity related differences in MCP-1 and adiponectin expression in subcutaneous adipose tissue in cats.
Jensen, Kathrine Stenberg, Novotny, G. W., Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2013
- Published
Anti-cytokine therapies in T1D: Concepts and strategies
Nepom, G. T., Ehlers, M. & Mandrup-Poulsen, Thomas, Dec 2013, In: Clinical Immunology. 149, 3 Part A, p. 279-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Total and cause-specific mortality by elevated transferrin saturation and hemochromatosis genotype in individuals with diabetes - two general population studies
Ellervik, Christina, Mandrup-Poulsen, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 15 Oct 2013, In: Diabetes Care. 37, 2, p. 444-452 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age-dependent decline of β cell function in type 1 diabetes after diagnosis: a multi-centre longitudinal study
Barker, V. A., Lauria, A., Schloot, N., Hosszufalusi, N., Ludvigsson, J., Mathieu, C. J., Mauricio, D., Nordwall, M., Van der Schueren, B., Mandrup-Poulsen, Thomas, Scherbaum, W., Weets, I., Gorus, F., Wareham, N., Leslie, R. & Pozzilli, P., 1 Oct 2013, In: Diabetes, Obesity and Metabolism Online. 16, 3, p. 262-267 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HDAC3 inhibition rescues pancreatic beta cells from glucolipotoxicity and improves insulin secretion in obese diabetic rats
Lundh, M., Galbo, T., Wagner, F. F., Christensen, D. P., Walpita, D., Gale, J. P., Zhang, Y., Hooker, J., Shulman, G. I., Mandrup-Poulsen, Thomas, Holson, E. B. & Wagner, B. K., Sep 2013, In: Diabetologia. 56, 1 suppl, p. S219-S219Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-molecule inhibition of inflammatory β-cell death
Lundh, M., Scully, S. S., Mandrup-Poulsen, Thomas & Wagner, B. K., Sep 2013, In: Diabetes, Obesity and Metabolism Online. 15 , 3, p. 176-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Total mortality by elevated transferrin saturation in patients with diabetes
Ellervik, Christina, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M. M., Birgens, H., Nordestgaard, Børge & Mandrup-Poulsen, Thomas, Sep 2013, In: Diabetes Care. 36, 9, p. 2646-54 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-1 antagonists for diabetes
Mandrup-Poulsen, Thomas & AIDA study group, A. S. G., Aug 2013, In: Expert Opinion on Investigational Drugs. 22, 8, p. 965-79 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes mellitus: a metabolic autoinflammatory disease
Mandrup-Poulsen, Thomas, Jul 2013, In: Dermatologic Clinics. 31, 3, p. 495-506 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials
Moran, A., Bundy, B., Becker, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Greenbaum, C. J., Herold, K. C., Marks, J. B., Raskin, P., Sanda, S., Schatz, D., Wherrett, D. K., Wilson, D. M., Krischer, J. P., Skyler, J. S., Pickersgill, L., de Koning, E., Ziegler, A-G., Böehm, B. & 12 others, , 1 Jun 2013, In: Lancet. 381, 9881, p. 1905-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer term type 1 diabetes
Pham, M., Kolb, H., Battelino, T., Ludvigsson, J., Pozzilli, P., Zivehe, F., Roden, M., Mandrup-Poulsen, Thomas, Schloot, N. C. & European C-Peptide Trial, E. C. T., Jun 2013, In: Diabetologia. 56, 6, p. 1356-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum adipokines as biomarkers of beta-cell function in patients with type 1 diabetes: positive association with leptin and resistin and negative association with adiponectin
Pham, M. N., Kolb, H., Mandrup-Poulsen, Thomas, Battelino, T., Ludvigsson, J., Pozzilli, P., Roden, M., Schloot, N. C. & European C-Peptide Trial, E. C. T., Feb 2013, In: Diabetes - Metabolism: Research and Reviews (Online). 29, 2, p. 166-70 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The lysine deacetylase inhibitor givinostat inhibits ß-cell IL-1ß induced IL-1ß transcription and processing
Dahllöf, M. S., Christensen, D. P., Lundh, M., Dinarello, C. A., Mascagni, P., Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Nov 2012, In: Islets. 4, 6, p. 417-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TiSH--a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC
Engholm-Keller, K., Birck, P., Størling, Joachim, Pociot, Flemming, Mandrup-Poulsen, Thomas & Larsen, M. R., 22 Oct 2012, In: International Journal of Proteomics. 75, 18, p. 5749-61 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth differences between North American and European children at risk for type 1 diabetes
Nucci, A. M., Becker, D. J., Virtanen, S. M., Cuthbertson, D., Softness, B., Huot, C., Wasikowa, R., Dosch, H. M., Akerblom, H. K., Knip, M., TRIGR Study Group, T. S. G. & Mandrup-Poulsen, Thomas, Aug 2012, In: Pediatric Diabetes Online. 13, 5, p. 425-31 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA modifications by oxidation: a novel disease mechanism?
Poulsen, Henrik Enghusen, Specht, E., Broedbaek, K., Henriksen, T., Ellervik, Christina, Mandrup-Poulsen, Thomas, Tonnesen, M., Nielsen, Peter E., Andersen, H. U. & Weimann, A., Apr 2012, In: Free Radical Biology & Medicine. 52, 8, p. 1353-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
(19)F-heptuloses as tools for the non-invasive imaging of GLUT2-expressing cells
Malaisse, W. J., Zhang, Y., Louchami, K., Sharma, S., Dresselaers, T., Himmelreich, U., Novotny, G. W., Mandrup-Poulsen, Thomas, Waschke, D., Leshch, Y., Thimm, J., Thiem, J. & Sener, A., 2012, In: Archives of Biochemistry and Biophysics. 517, 2, p. 138-43 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between age, IL-10, IFN¿, stimulated C-peptide and disease progression in children with newly diagnosed Type 1 diabetes
Kaas, A., Pfleger, C. C., Kharagjitsingh, A. V., Schloot, N. C., Hansen, L., Buschard, K., Koeleman, B. P. C., Roep, B. O., Mortensen, H. B., Alizadeh, B. Z., Hvidoere Study Group On Childhood Diabetes, H. S. G. O. C. D. & Mandrup-Poulsen, Thomas, 2012, In: Diabetic Medicine Online. 29, 6, p. 734-741 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-Cell Specific DMT1 KO Protects Islets from Cytokine Induced ROS and Apoptosis
Hansen, J. B., Heller, S., Madsen, A. N., Holst, Birgitte, Tonnesen, M. F. & Mandrup-Poulsen, Thomas, 2012.Research output: Contribution to conference › Poster › Research › peer-review
ID: 923693
Most downloads
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780
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Tissue inhibitor of matrix metalloproteinase-1 is required for high-fat diet-induced glucose intolerance and hepatic steatosis in mice
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
210
downloads
JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
199
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A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats
Research output: Contribution to journal › Journal article › Research › peer-review
Published