Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer term type 1 diabetes

Research output: Contribution to journalJournal articleResearchpeer-review

  • Minh-Long Pham
  • H Kolb
  • T Battelino
  • J Ludvigsson
  • P Pozzilli
  • F Zivehe
  • M Roden
  • Mandrup-Poulsen, Thomas
  • N C Schloot
  • European C-Peptide Trial
Cytokines may promote or inhibit disease progression in type 1 diabetes. We investigated whether systemic proinflammatory, anti-inflammatory and regulatory cytokines associated differently with fasting and meal-stimulated beta cell function in patients with longer term type 1 diabetes.
Original languageEnglish
JournalDiabetologia
Volume56
Issue number6
Pages (from-to)1356-63
Number of pages8
ISSN0012-186X
DOIs
Publication statusPublished - Jun 2013

    Research areas

  • Adolescent, Adult, Blood Glucose, Body Mass Index, C-Peptide, Child, Cytokines, Diabetes Mellitus, Type 1, Diet, Fasting, Female, Gene Expression Regulation, Humans, Inflammation, Insulin-Secreting Cells, Male, Time Factors, Young Adult

ID: 96512687