Flemming Dela
Professor
Exercise and Muscle
Blegdamsvej 3
2200 København N.
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Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men
Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Faerch, K., Hiscock, N., Mortensen, B., Friedrichsen, M., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 1 Nov 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 5, p. E752-63 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin resistance and mitochondrial function in skeletal muscle
Dela, Flemming & Helge, Jørn Wulff, Jan 2013, In: International Journal of Biochemistry & Cell Biology. 45, 1, p. 11-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin resistance and exercise tolerance in heart failure patients: linkage to coronary flow reserve and peripheral vascular function
Snoer, Martin, Monk-Hansen, T., Olsen, R. H., Pedersen, L. R., Simonsen, L., Rasmusen, H., Dela, Flemming & Prescott, Eva, 2012, In: Cardiovascular Diabetology. 11, p. 97Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin and non-insulin mediated vasodilation and glucose uptake in patients with type 2 diabetes
Scheede-Bergdahl, C., Olsen, D. B., Reving, D., Boushel, R. & Dela, Flemming, 2009, In: Diabetes Research and Clinical Practice. 85, 3, p. 243-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin action, training, and aging
Dela, Flemming, Holten, M. & Jensen, C. M., 2001, In: Int J Sport Nutr Exerc Metab. 11, p. S78-S85Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin action and long-term electrically induced training in individuals with spinal cord injuries
Mohr, T. T., Dela, Flemming, Handberg, A., Biering-Sørensen, Fin, Galbo, Henrik & Kjær, Michael, 2001, In: Medicine and Science in Sports and Exercise. 33, p. 1247-1252Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans
Asmar, M., Simonsen, L., rck626, rck626, Holst, Jens Juul, Dela, Flemming & Bülow, J., Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3155-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus
Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of maximal fat oxidation on long-term weight loss maintenance in humans
Dandanell, S., Husted, Karina Louise Skov, Amdisen, S., Vigelso, A., Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, Jul 2017, In: Journal of Applied Physiology. 123, 1, p. 267-274 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans
Larsen, Steen, Dandanell, S., Kristensen, K. B., Jorgensen, S. D., Dela, Flemming & Helge, Jørn Wulff, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, 9, p. 958-964Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of erythropoietin on cognitive performance during experimental hypoglycemia in patients with type 1 diabetes mellitus: A Randomized Cross-Over Trial
Kristensen, Peter Lommer, Pedersen-Bjergaard, Ulrik, Kjær, T. W., Olsen, N. V., Dela, Flemming, Holst, Jens Juul, Faber, Jens, Tarnow, L. & Thorsteinsson, B., 5 Apr 2013, In: P L o S One. 8, 4, p. 1-8 8 p., e59672.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of age on leptin induced skeletal muscle signaling
Guadalupe Grau, A., Larsen, Steen, Guerra, B., Calbet, J. A., Dela, Flemming & Helge, Jørn Wulff, 8 Mar 2014, In: Acta Physiologica. 211, 1, p. 214-228 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Zach, Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, Astrid Elisabeth Bruun, Olsen, B. H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, S., Bendtsen, Flemming & Dela, Flemming, 2022, In: Nature Communications. 13, 15 p., 2931.Research output: Contribution to journal › Journal article › Research › peer-review
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Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation
Hansen, M., Kuhlman, A. C. B., Sahl, Ronni Eg, Kelly, B., Morville, T., Dohlmann, T. L., Chrøis, K. M., Larsen, S., Helge, Jørn Wulff & Dela, Flemming, 2019, In: Cytokine. 113, p. 393-399 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased rate of whole body lipolysis before and after 9 days of bed rest in healthy young men born with low birth weight
Alibegovic, A. C., Hojbjerre, L., Sonne, M., van Hall, Gerrit, Alsted, T. J., Kiens, Bente, Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E555-E564 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased post-operative cardiopulmonary fitness in gastric bypass patients is explained by weight loss
Lund, M. T., Hansen, M., Wimmelmann, Cathrine Lawaetz, Taudorf, L. R., Helge, Jørn Wulff, Mortensen, Erik Lykke & Dela, Flemming, Dec 2016, In: Scandinavian Journal of Medicine & Science in Sports. 26, 12, p. 1428-1434 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue
Nielsen, B., Cejvanovic, V., Wortwein, G., Hansen, A. R., Marstal, K. K., Weimann, A., Bjerring, P. N., Dela, Flemming, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2019, In: Neuroscience Letters. 690, p. 1-5Research output: Contribution to journal › Journal article › Research › peer-review
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Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes
Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Andersen, J. L., Madsbad, Sten, Worm, Dorte, Helge, Jørn Wulff & Dela, Flemming, 2011, In: Diabetologia. 54, 6, p. 1427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased lipolysis but diminished gene expression of lipases in subcutaneous adipose tissue of healthy young males with intrauterine growth retardation
Højbjerre, L., Alibegovic, A. C., Sonne, M. P., Dela, Flemming, Vaag, Allan, Bruun, J. M. & Stallknecht, Bente Merete, 2011, In: Journal of Applied Physiology. 111, 6, p. 1863-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H
Larsen, Steen, Díez-Sánchez, C., Rabøl, R., Ara, I., Dela, Flemming & Helge, Jørn Wulff, Feb 2014, In: Biochimica et Biophysica Acta - Bioenergetics. 1837, 2, p. 226-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increase in IL-6, TNF-a, and MMP-9, but not sICAM-1, concentrations depends on exercise duration
Reihmane, D., Jurka, A., Tretjakovs, P. & Dela, Flemming, Apr 2013, In: European Journal of Applied Physiology. 113, 4, p. 851-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition
Rosenkilde Larsen, M., Morville, T., Riis Andersen, P., Kjær, K., Rasmusen, H., Holst, Jens Juul, Dela, Flemming, Westerterp, K., Sjödin, Anders Mikael & Helge, Jørn Wulff, 2015, In: American Journal of Clinical Nutrition. 102, 6, p. 1398-1405 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes
Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Diabetic Medicine. 11, 4, p. 355-60 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved glucose tolerance after high-load strength training in patients undergoing dialysis
Mølsted, Stig, Harrison, Adrian Paul, Eidemak, I., Dela, Flemming & Andersen, J. L., 2013, In: Nephron Clinical Practice. 123, 1-2, p. 134-141 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis
Nakajima, T., Yokota, T., Shingu, Y., Yamada, A., Iba, Y., Ujihira, K., Wakasa, S., Ooka, T., Takada, S., Shirakawa, R., Katayama, T., Furihata, T., Fukushima, A., Matsuoka, R., Nishihara, H., Dela, Flemming, Nakanishi, K., Matsui, Y. & Kinugawa, S., 2019, In: Scientific Reports. 9, 1, 3535.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired mitochondrial oxidative phosphorylation and fatty acid oxidation with enhanced mitochondrial oxidative stress in spontaneously-occurring feline hypertrophic cardiomyopathy
Yokota, T., Christiansen, L. B. & Dela, Flemming, Oct 2014, In: Journal of Cardiac Failure. 20, 10 supplement, p. S147 1 p., O-008.Research output: Contribution to journal › Conference abstract in journal › Research
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Impaired mitochondrial function in chronically ischemic human heart
Stride, N. O., Larsen, Steen, Hey-Mogensen, M., Hansen, C., Prats, C., Steinbrüchel, D., Køber, Lars Valeur & Dela, Flemming, 2013, In: A J P: Heart and Circulatory Physiology (Online). 304, 11, p. H1407-H1414 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired mitochondrial function in chronically ischemic human heart
Stride, N., Larsen, Steen, Hey-Mogensen, M., Hansen, C. N., Prats Gavalda, Clara, Steinbrüchel, D., Køber, Lars Valeur & Dela, Flemming, 1 Jun 2013, In: American Journal of Physiology: Heart and Circulatory Physiology. 304, 11, p. H1407-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired endothelial function and insulin action in first-degree relatives of patients with type 2 diabetes mellitus
Sonne, M. P., Højbjerre, L., Alibegovic, A. A., Vaag, Allan, Stallknecht, Bente Merete & Dela, Flemming, 2009, In: Metabolism - Clinical and Experimental. 58, 1, p. 93-101 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy
Christiansen, L. B., Dela, Flemming, Koch, Jørgen, Hansen, C. N., Leifsson, Páll S. & Yokota, T., 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 308, 10, p. H1237-H1247 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of sedentarism due to the COVID-19 home confinement on neuromuscular, cardiovascular and metabolic health: Physiological and pathophysiological implications and recommendations for physical and nutritional countermeasures
Narici, M., De Vito, G., Franchi, M., Paoli, A., Moro, T., Marcolin, G., Grassi, B., Baldassarre, G., Zuccarelli, L., Biolo, G., di Girolamo, F. G., Fiotti, N., Dela, Flemming, Greenhaff, P. & Maganaris, C., 2021, In: European Journal of Sport Science. 21, 4, p. 614 - 635Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of polymorphism in the β₂-receptor gene on metabolic responses to repeated hypoglycaemia in healthy humans
Rokamp, K. Z., Holst, Jens Juul, Olsen, N. V., Dela, Flemming, Secher, Niels H., Juul, Anders, Faber, Jens, Wiberg, S., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 8, p. e3194–e3205 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of physical inactivity on subcutaneous adipose tissue metabolism in healthy young male offspring of patients with type 2 diabetes
Højbjerre, L., Sonne, M., Alibegovic, A., Dela, Flemming, Vaag, A., Bruun, J. M., Christensen, Karl Bang & Stallknecht, Bente Merete, Nov 2010, In: Diabetes. 59, 11, p. 2790-2798 90 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of physical inactivity on adipose tissue low-grade inflammation in first-degree relatives of type 2 diabetic patients
Højbjerre, L., Sonne, M. P., Alibegovic, A. C., Nielsen, N. B., Dela, Flemming, Vaag, Allan, Bruun, J. M. & Stallknecht, Bente Merete, 2011, In: Diabetes Care. 34, 10, p. 2265-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of Polymorphism in the β2-Receptor Gene on the Metabolic Response to Epinephrine After Repeated Hypoglycemia
Rokamp, K. Z., Dela, Flemming, Secher, Niels H., Grønlykke, L., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2023, In: Diabetes. 72, 6, p. 728-734Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of 9 days of bed rest on hepatic and peripheral insulin action, insulin secretion, and whole-body lipolysis in healthy young male offspring of patients with type 2 diabetes
Alibegovic, A. C., Højbjerre, L., Sonne, M. P., van Hall, G., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2009, In: Diabetes. 58, 12, p. 2749-56 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunological effects of a hyperinsulinaemic euglycaemic insulin clamp in healthy males.
Kappel, M., Dela, Flemming, Barington, T., Galbo, Henrik & Pedersen, B. K., 1998, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 47, p. 363-368Research output: Contribution to journal › Journal article › Research › peer-review
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Immobilization increases interleukin-6, but not tumour necrosis factor-a, release from the leg during exercise in humans
Reihmane, D., Hansen, A. V., Jensen, M. G., Kuhlman, A. B., Nørregaard, J., Pedersen, H. P., Lund, M. T., Helge, Jørn Wulff & Dela, Flemming, Mar 2013, In: Experimental Physiology. 98, 3, p. 778-83 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hvad kan vi lære af årtiers kolesteroldebat? kampen om kolesterolet
Lau, Sofie Rosenlund, Andersen, John Sahl, Dela, Flemming & Oxlund, Bjarke, 2020, In: Månedsskrift for praktisk lægegerning. 1, p. 831-838Research output: Contribution to journal › Journal article › Research › peer-review
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Human skeletal muscle perilipin 2 and 3 expression varies with insulin sensitivity
Vigelsø Hansen, A., Prats Gavalda, Clara, Ploug, Thorkil, Dela, Flemming & Helge, Jørn Wulff, May 2013, In: Journal of Biomedical Science and Engineering. 6, 5A, p. 65-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity
Skovbro, M., Baranowski, M., Skov-Jensen, C., Flint, A., Dela, Flemming, Gorski, J. & Helge, Jørn Wulff, 2008, In: Diabetologia. 51, 7, p. 1253-60 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men
Vigelsø Hansen, A., Prats Gavalda, Clara, Ploug, Thorkil, Dela, Flemming & Helge, Jørn Wulff, 2016, In: Physiological Research. 65, 2, p. 293-302 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-intensity interval training improves insulin sensitivity in older individuals
Søgaard, D., Lund, M. T., Scheuer, C. M., Dehlbaek, M. S., Dideriksen, S. G., Abildskov, C. V., Christensen, K. K., Dohlmann, T. L., Larsen, Steen, Vigelsø, A. H., Dela, Flemming & Helge, Jørn Wulff, Apr 2018, In: Acta Physiologica (Print). 222, 4, e13009.Research output: Contribution to journal › Journal article › Research › peer-review
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High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle
Dohlmann, T. L., Hindsø, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 1 Sep 2018, In: Physiological Reports. 6, 18, p. 1-11 e13857.Research output: Contribution to journal › Journal article › Research › peer-review
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High-fat feeding inhibits exercise-induced increase in mitochondrial respiratory flux in skeletal muscle
Skovbro, M., Boushel, R. C., Hansen, C. N., Helge, Jørn Wulff & Dela, Flemming, 2011, In: Journal of Applied Physiology. 110, 6, p. 1607-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression
Davidsen, P. K., Gallagher, I. J., Hartman, J. W., Tarnopolsky, M. A., Dela, Flemming, Helge, Jørn Wulff, Timmons, J. A. & Phillips, S. M., 2011, In: Journal of Applied Physiology. 110, 2, p. 309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes
Lund, M. T., Kristensen, M. D., Hansen, M., Tveskov, L., Floyd, A. K., Støckel, M., Vainer, B., Poulsen, Steen Seier, Helge, Jørn Wulff, Prats Gavalda, Clara & Dela, Flemming, 6 Apr 2016, In: The Journal of Physiology. 594, 15, p. 4351-4358 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic fat content decreases with 3 weeks of intermittent fasting in obese patients with and without type 2 diabetes
Ingersen, Arthur, Helset, H., Skaaby, Stinna, Calov, M., Chabanova, E., Helge, Jørn Wulff & Dela, Flemming, Aug 2016, In: Diabetologia. 59, S1, p. S78-S78Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Heart rate and plasma catecholamines during 24 h of everyday life in trained and untrained men
Dela, Flemming, Mikines, K. J., Linstow, M. V. & Galbo, Henrik, 1992, In: Journal of Applied Physiology. Vol 73, p. 2389-2395Research output: Contribution to journal › Journal article › Research › peer-review
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Glut 4 and insulin receptor binding and kinase activity in trained human muscle
Dela, Flemming, Handberg, A., Mikines, K. J., Vinten, J. & Galbo, Henrik, 1993, In: Journal of Physiology. Vol. 469, p. 615-624Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10200
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The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
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