Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes

    Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

    Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, Hulot, J., Lewinter, C., Pedersen, H. K., Quinquis, B., Rouault, C., Roume, H., Salem, J., Søndertoft, N. B., Touch, S., Dumas, M., Ehrlich, S. D., Galan, P., Gøtze, J. P., Hansen, Torben, Holst, Jens Juul, Køber, Lars Valeur, Letunic, I., Nielsen, J., Oppert, J., Stumvoll, M., Vestergaard, H., Zucker, J., Bork, P., Pedersen, Oluf Borbye, Bäckhed, F., Clément, K., Raes, J. & MetaCardis Consortium, M. C., 2020, In: Nature. 581, 7808, p. 310-315

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

    Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Stability of glucagon-like peptide-1 and glucagon in human plasma

    Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

    Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hartmann, Bolette, Christensen, M., Vilsbøll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: European Journal of Endocrinology. 170, 4, p. 529-538 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Specific inhibition of bile acid transport alters plasma lipids and GLP-1

    Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors

    wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Somostatin and Prosomatostatin-immunoreactive nerve fibers in the bovine pineal gland

    Møller, M., Mikkelsen, J. D. & Holst, Jens Juul, 1992, In: Neuroendocrinology. Vol. 56 (2), p. 278-283

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Somatostatin receptors.

    Møller, L. N., Stidsen, C. E., Hartmann, B. & Holst, Jens Juul, 2003, In: BBA General Subjects. 1616, 1, p. 1-84 83 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Somatostatin is an essential paracrine link in acid inhibition of gastrin secretion

    Holst, Jens Juul, Ørskov, Cathrine & Poulsen, S. S., 1992, In: Digestion. 51, p. 95-102

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Somastostatin restrains the secretion of glucagon-like peptide-1 and 2 (GLP-1 and GLP-2) from isolated perfused porcine ileum

    Hansen, L., Hartmann, B., Bisgaard, T., Mineo, H., Jørgensen, P. N. & Holst, Jens Juul, 2000, In: Am. J. Physiol.. 278, p. E1010-E1018

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Small-molecule agonists for the glucagon-like peptide 1 receptor

    Knudsen, L. B., Kiel, D., Teng, M., Behrens, C., Bhumralkar, D., Kodra, J. T., Holst, J. J., Jeppesen, C. B., Johnson, M. D., de Jong, J. C., Jorgensen, A. S., Kercher, T., Kostrowicki, J., Madsen, P., Olesen, P. H., Petersen, J. S., Poulsen, F., Sidelmann, U. G., Sturis, J., Truesdale, L. & 2 others, May, J. & Lau, J., 16 Jan 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 3, p. 937-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Farooqi, I. S., Raffin-Sanson, M-L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J. & 2 others, Lindley, K. J. & O'Rahilly, S., Nov 2003, In: The Journal of Clinical Investigation. 112, 10, p. 1550-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor

    Teng, M., Johnson, M. D., Thomas, C., Kiel, D., Lakis, J. N., Kercher, T., Aytes, S., Kostrowicki, J., Bhumralkar, D., Truesdale, L., May, J., Sidelman, U., Kodra, J. T., Jørgensen, A. S., Olesen, P. H., Jong, J. C. D., Madsen, P., Behrens, C., Pettersson, I., Knudsen, L. B. & 2 others, Holst, Jens Juul & Lau, J., 2007, In: Bioorganic & Medicinal Chemistry Letters. 17, 19, p. 5472-5478 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Small intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Saraf Faraoqi, I., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicholl, T. M., Lindley, K. J. & 1 others, O Rahlly, S., 2003, In: J. Clin. Invest.. 112, p. 1550-1560

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes

    Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes

    Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  20. Published

    Sitagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with short bowel syndrome and colon in continuity: an open-label pilot study

    Naimi, R. M., Hvistendahl, M. K., Thomassen, L. M., Johnsen, H., Christiansen, Charlotte Bayer, Holst, Jens Juul, Hartmann, Bolette & Jeppesen, Palle Bekker, 2021, In: BMJ Open Gastroenterology. 8, 1, 10 p., e000604.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes

    Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8

    Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.

    Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In: Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Similar incretin secretion in obese and non-obese Japanese subjects with type 2 diabetes

    Kozawa, J., Okita, K., Imagawa, A., Iwahashi, H., Holst, Jens Juul, Yamagata, K. & Shimomura, I., 12 Mar 2010, In: Biochemical and Biophysical Research Communications. 393, 3, p. 410-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Similar gastric emptying but greater gastric secretion and GIP release after the ingestion of peptide hydrolysates in man

    Calbet, J. A. L. & Holst, Jens Juul, 2004, In: Eur J Nutrition. 43, p. 127-139

    Research output: Contribution to journal › Journal article › Research › peer-review

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