Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP).

    Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Regulatory Peptides. 113, 1-3, p. 95-100 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men

    Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., 2006, In: Journal of Nutrition. 136, 6, p. 1511-1516 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men

    Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., Jun 2006, In: Journal of Nutrition. 136, 6, p. 1511-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

    van der Beek, C. M., Canfora, E. E., Kip, A. M., Gorissen, S. H. M., Damink, S. W. M. O., van Eijk, H. M., Holst, Jens Juul, Blaak, E. E., Dejong, C. H. C. & Lenaerts, K., Oct 2018, In: Metabolism. 87, p. 25-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The physiology of glucagon-like peptide 1.

    Holst, Jens Juul, 2007, In: Physiological Reviews. 87, 4, p. 1409-39 30 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The physiology and pharmacology of incretins in type 2 diabetes mellitus

    Holst, Jens Juul, 2008, In: Diabetes, Obesity and Metabolism. 10, Suppl. 3, p. 14-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.

    Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The pathogenesis of diabetes involves a defective amplication of the late phase insulin response to glucose by GIP - regardless of aetiology and phenotype

    Vilsbøll, T., Knop, F., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T., Pedersen, O. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 4897-4903

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, S., Deacon, Carolyn F. & Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 369-374 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

    Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The liver–alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels

    Gar, C., Haschka, S. J., Kern-Matschilles, S., Rauch, B., Sacco, V., Prehn, C., Adamski, J., Seissler, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Lechner, A., 2021, In: Diabetologia. 64, 3, p. 512-520

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes

    Otten, J., Stomby, A., Waling, M., Chorell, E., Ryberg, M., Svensson, M., Holst, Jens Juul & Olsson, T., 2021, In: Endocrine Connections. 10, 9, p. 1101-1110

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The liver-alpha cell axis and type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, Filip Krag & Holst, Jens Juul, 2019, In: Endocrine Reviews. 40, 5, p. 1353-1366

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.

    Hare, K. J., Hartmann, B., Kissow, Hannelouise, Holst, Jens Juul & Poulsen, Steen Seier, 2007, In: Clinical Cancer Research. 13, 17, p. 5170-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

    Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Toräng, S. & Holst, Jens Juul, 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  20. Published

    The insulinotropic effect of exogenous GLP-1 is not affected by acute vagotomy in anaesthetized pigs

    Veedfald, Simon, Hansen, M., Christensen, L. W., Larsen, S. A. H., Hjøllund, K. R., Plamboeck, A., Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, 30 Mar 2016, In: Experimental Physiology. 101, 7, p. 895-912 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells

    Salehi, A., Gunnerud, U., Muhammed, S. J., Ostman, E., Holst, Jens Juul, Björck, I. & Rorsman, P., 2012, In: Nutrition & Metabolism. 9, 1, p. 48

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.

    Wettergren, A., Wøjdemann, M., Meisner, S., Stadil, F. & Holst, Jens Juul, 1997, In: Gut. 40, p. 597-601

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The inhibitory effect of glucagon-like peptide-1 (7-36) amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36) amide.

    Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Peptides. 19, p. 877-882

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The influence of nutrients, biliary-pancreatic secretions, and systemic trophic hormones on intestinal adaptation in a Roux-en-Y bypass model

    Taqi, E., Wallace, L. E., de Heuvel, E., Chelikani, P. K., Zheng, H., Berthoud, H., Holst, Jens Juul & Sigalet, D. L., 1 May 2010, In: European Journal of Pediatric Surgery. Supplement. 45, 5, p. 987-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes

    Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The influence of GLP-1 on glucose-induced insulin secretion: effect on ß-cells sensitivity in type 2 and non-diabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. A. & Madsbad, S., 2003, In: Diabetes. 52, p. 380-386

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The incretin/glucagon system as a target for pharmacotherapy of obesity

    Del Prato, S., Gallwitz, B., Holst, Jens Juul & Meier, J. J., 2022, In: Obesity Reviews. 23, 2, 13 p., e13372.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The incretin system in healthy humans: The role of GIP and GLP-1

    Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The incretin system and its role in type 2 diabetes mellitus

    Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The incretin enhancer vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed -cell function in patients with type 2 diabetes

    Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, p. 4888-4894

    Research output: Contribution to journal › Journal article › Research

  33. Published

    The incretin effect in patients with maturity onset diabetes of the young

    Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The incretin effect does not differ in trained and untrained, young, healthy men

    Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.

    Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake

    Jensen, C. H., Kosmina, R., Rydén, M., Baun, C., Hvidsten, S., Andersen, M. S., Christensen, L. L., Gastaldelli, A., Marraccini, P., Arner, P., Jørgensen, C. D., Laborda, J., Holst, Jens Juul & Andersen, D. C., 2019, In: EBioMedicine. 46, p. 368-380 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

    Christiansen, Charlotte Bayer, Gabe, M. B. N., Svendsen, B., Dragsted, Lars Ove, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency

    Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes

    Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  43. Published

    The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  44. Published

    The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes

    Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans

    Jensen, P. B., Kristensen, P., Clausen, J. T., Judge, M. E., Hastrup, S., Thim, L., Wulff, B. S., Foged, C., Jensen, J., Holst, Jens Juul & Madsen, O. D., 1999, In: FEBS Letters. 447, p. 139-143

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk

    Gunnerud, U., Holst, Jens Juul, Östman, E. & Björck, I., 2012, In: Nutrition Journal. 11, p. 83

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1

    Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.

    Research output: Contribution to journal › Conference abstract in journal › Research

  48. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

    Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study

    Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  50. Published

    The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.

    Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine

    Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants

    Sigalet, D. L., Lam, V., Brindle, M., Boctor, D., Wallace, L., de Heuval, E., Hartmann, Bolette & Holst, Jens Juul, 2018, In: Journal of Pediatric Surgery. 53, 5, p. 898-904

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat

    Poulsen, Steen Seier & Holst, Jens Juul, 1988, In: Digestion. 40, 3, p. 144-51 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    The feedback cycles between glucose, amino acids and lipids and alpha cell secretion and their role in metabolic fatty liver disease

    Winther-Sørensen, Marie, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Current Opinion in Lipidology. 34, 1, p. 27-31

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    The expanding incretin universe: from basic biology to clinical translation

    Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779

    Research output: Contribution to journal › Review › Research › peer-review

  57. Published

    The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    The ethanol augmentation of glucose-induced insulin secretion is abolished by calcium antagonism with nifedipine: No evidence for a role of glucagon-like peptide-1 (GLP-1)

    Svartberg, J., Holst, Jens Juul, Gutniak, M. K. & Adner, N., 1998, In: Pancreas. 16, p. 66-71

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

    Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., de Heuval, E. & Sigalet, D. L., 31 Oct 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-45 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    The effects of postprandial exercise and meal glycemic index on plasma glucose and glucoregulatory hormone responses after Roux-en-Y gastric bypass

    Ternhamar, T., Møller, A., Martinussen, C., Svane, M. S., Hindsø, M., Jørgensen, N. B., Dirksen, C., Jensen, Jens-Erik Beck, Hartmann, Bolette, Holst, Jens Juul, Kiens, Bente, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 5, p. E540-E551 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    The effects of gastric emptying on the postprandial ghrelin response

    Blom, W., Lluch, A., Vinoy, S., Stafleu, A., Van den Berg, R., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. K., 2006, In: Am. J. Physiol.. 290, p. E389-E395

    Research output: Contribution to journal › Journal article › Research

  64. Published

    The effects of exercise-induced weight loss on appetite-related peptides and motivation to eat

    Martins, C., Kulseng, B., King, N. A., Holst, Jens Juul & Blundell, J. E., 1 Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1609-16 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop?

    Hansen, L. & Holst, Jens Juul, 31 Dec 2002, In: Regulatory Peptides. 110, 1, p. 39-45 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs

    Bosch, G., Verbrugghe, A., Hesta, M., Holst, Jens Juul, van der Poel, A. F. B., Janssens, G. P. J. & Hendriks, W. H., 2009, In: British Journal of Nutrition. 102, 2, p. 318-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics

    Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans

    Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake

    Sørensen, L. B., Cueto, H. T., Andersen, M. T., Bitz, C., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 5, p. 1163-1169 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    The effect of preceding glucose decline rate on low-dose glucagon efficacy in individuals with type 1 diabetes: A randomized crossover trial

    Laugesen, C., Schmidt, S., Holst, Jens Juul, Nørgaard, Kirsten & Ranjan, A. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 4, p. 1057-1062 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    The effect of melatonin on incretin hormones: results from experimental and randomized clinical studies

    Lauritzen, E. S., Støy, J., Bæch-Laursen, C., Grarup, Niels, Jessen, N., Hansen, Torben, Møller, N., Hartmann, Bolette, Holst, Jens Juul & Kampmann, U., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. e5109-e5123 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man

    Øktedalen, O., Opstad, P. K. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 652-656

    Research output: Contribution to journal › Journal article › Research

  73. Published

    The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters

    Bremholm, L., Hornum, Mads, Andersen, U. B. & Holst, Jens Juul, 8 Jan 2010, In: Regulatory Peptides. 159, 1-3, p. 67-71 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans

    Flint, A., Raben, A., Rehfeld, J. F., Holst, Jens Juul & Astrup, A., 2000, In: International Journal of Obesity. 24, p. 288-298

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    The effect of glucagon-like peptide 1 on cardiovascular risk

    Sivertsen, J., Rosenmeier, J., Holst, Jens Juul & Vilsbøll, T., Apr 2012, In: Nature Reviews Cardiology. 9, 4, p. 209-22 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    The effect of glucagon-like Peptide-2 receptor agonists on colonic anastomotic wound healing

    Redstone, H. A., Buie, W. D., Hart, D. A., Wallace, L., Hornby, P. J., Sague, S., Holst, Jens Juul & Sigalet, D. L., 1 Jan 2010, In: Gastroenterology Research and Practice. 2010, p. Article ID 672453 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity

    Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys

    Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    The effect of dietary carbohydrate restriction beyond weight loss on health-related quality of life and cognition

    Jensen, N. J., Wodschow, H. Z., fbg982, fbg982, Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Rungby, Jørgen, Haugaard, Steen Bendix & Thomsen, M. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 62-63 114.

    Research output: Contribution to journal › Conference abstract in journal › Research

  80. Published

    The effect of curcumin on hepatic fat content in individuals with obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects

    Schmedes, M. S., Bendtsen, L. Q., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael, Astrup, A., Young, J. F., Sundekilde, U. K. & Bertram, H. C., 2018, In: Journal of the Science of Food and Agriculture. 98, 15, p. 5598-5605 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery

    Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women

    Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    The effect of a subcutaneous infusion of GLP-1, OXM and PYY on Energy intake and Expenditure in Obese volunteers

    Tan, T., Behary, P., Tharakan, G., Minnion, J., Al-Najim, W., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Bloom, S. R., 1 Jul 2017, In: The Journal of clinical endocrinology and metabolism. 102, 7, p. 2364-2372 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: British Journal of Nutrition. 101, 12, p. 1846-1858 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    The effect of a high monounsaturated fatty acid, low glycemic index diet and a low fat diet on satiety, appetite regulatory hormones and glucose metabolism during a 6 mo weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S204 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  87. Published

    The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial

    Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    The effect of Roux-en-Y gastric bypass surgery on energy expenditure and appetite: a randomized human study including “pair fed” control subjects

    Schmidt, J. B., Gregersen, N. T., Pedersen, S., Nielsen, M. S., Nielsen, L. V., Holst, Jens Juul, Hansen, D. L., Dorm, D. W., Madsbad, Sten, Clausen, T. R. C., Ritz, C., Astrup, A. & Sjödin, Anders Mikael, 2013, In: Obesity Facts. 6, suppl. 1, p. 28 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  89. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

    Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults

    Nilsson, M., Bové, K. B., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., Mar 2019, In: IJC Heart and Vasculature. 22, p. 139-144

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults

    Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  92. Published

    The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose

    Bock, G., Man, C. D., Micheletto, F., Basu, R., Rn, P. D. G., Laugen, J., Deacon, Carolyn F., Holst, Jens Juul, Toffolo, G., Cobelli, C., Rizza, R. A. & Vella, A., 2010, In: Clinical Endocrinology. 73, p. 189-196

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    The effect o a high protein dairy breakfast on the postprandial ghrelin response

    Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. K., 2006, In: Am. J. Clin. Nutr.. 83, p. 211-220

    Research output: Contribution to journal › Journal article › Research

  95. Published

    The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes

    Hygum, K., Starup-Linde, J., Harslor, T., Jørgensen, Niklas Rye, Hartmann, Bolette, Holst, Jens Juul & Langdahl, B. L., 2019, In: European Journal of Endocrinology. 181, 3, p. 221-231

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable alpha- and beta-cell tumor phenotypes

    Madsen, O. D., Karlsen, C., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, Jens Frederik, Larsson, L. I., Steiner, D. F. & Holst, Jens Juul, Nov 1993, In: Endocrinology. 133, 5, p. 2022-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable *Ga- and *Gb-cell tumor phenotypes

    Madsen, O. D., Karlsen, G., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, J. F., Larsson, L., Steiner, D. F., Holst, Jens Juul & Michelsen, B. K., 1993, In: Endokrinologiya. vol. 133, no. 5, p. 2022-2030

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose

    Utzschneider, K. M., Tong, J., Montgomery, B., Udayasankar, J., Gerchman, F., Marcovina, S. M., Watson, C. E., Ligueros-Saylan, M. A., Foley, J. E., Holst, Jens Juul, Deacon, Carolyn F. & Kahn, S. E., 2007, In: Diabetes Care. 31, 1, p. 108-113 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.

    Balas, B., Baig, M. R., Watson, C., Dunning, B. E., Ligueros-Saylan, M., Wang, Y., He, Y., Darland, C., Holst, Jens Juul, Deacon, Carolyn F., Cusi, K., Mari, A., Foley, J. E. & DeFronzo, R. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1249-55 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion

    Ouaghlidi, A. E., Rehring, E., Holst, Jens Juul, Schweizer, A., Foley, J., Holmes, D. & Nauck, M. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 11, p. 4165-4171 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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