Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

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    1. Published

      Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

      Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, Jens Høiriis, Porse, Bo Torben, Mandrup-Poulsen, Thomas & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Interleukin-6 receptor blockade or TNF alpha inhibition for reducing glycaemia in patients with RA and diabetes: post hoc analyses of three randomised, controlled trials

      Genovese, M. C., Burmester, G. R., Hagino, O., Thangavelu, K., Iglesias-Rodriguez, M., John, G. S., Gonzalez-Gay, M. A., Mandrup-Poulsen, Thomas & Fleischmann, R., 2020, In: Arthritis Research & Therapy. 22, 1, 12 p., 206.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex.

      Frobøse, H., Rønn, S. G., Heding, P. E., Mendoza, H., Cohen, P., Mandrup-Poulsen, Thomas & Billestrup, N., 2006, In: Molecular Endocrinology. 20, 7, p. 1587-96 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expression

      Fred, R. G., Bang-Berthelsen, C. H., Mandrup-Poulsen, Thomas, Grunnet, L. G. & Welsh, N., 2010, In: PLoS ONE. 5, 5, p. e10843

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Lost in translation

      Frank, L. & Mandrup-Poulsen, Thomas, 2007, In: Weekendavisen. 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Recruitment and retention of participants for an international type 1 diabetes prevention trial: a coordinators' perspective

      Franciscus, M., Nucci, A., Bradley, B., Suomalainen, H., Greenberg, E., Laforte, D., Kleemola, P., Hyytinen, M., Salonen, M., Martin, M. J., Catte, D., Catteau, J., TRIGR Investigators, T. I. & Mandrup-Poulsen, Thomas, Apr 2014, In: Clinical Trials. 11, 2, p. 150-8 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J Mice

      Fjære, E., Aune, U. L., Røen, K., Keenan, A. H., Ma, Tao, Borkowski, K., Kristensen, D. M. B., Novotny, G. W., Mandrup-Poulsen, Thomas, Hudson, B. D., Milligan, G., Xi, Y., Newman, J. W., Haj, F. G., Liaset, B., Kristiansen, Karsten & Madsen, L., 2014, In: The Journal of Biological Chemistry. 289, 23, p. 16032-16045 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Tissue inhibitor of matrix metalloproteinase-1 is required for high-fat diet-induced glucose intolerance and hepatic steatosis in mice

      Fjære, E., Andersen, C., Myrmel, L. S., Petersen, R. K., Hansen, J. B., Tastesen, H. S., Mandrup-Poulsen, Thomas, Brünner, N., Kristiansen, Karsten, Madsen, L. & Rømer, M. U. K., 2015, In: PloS one. 10, 7, 19 p., e0132910.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      TiSH--a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC

      Engholm-Keller, K., Birck, P., Størling, Joachim, Pociot, Flemming, Mandrup-Poulsen, Thomas & Larsen, M. R., 22 Oct 2012, In: International Journal of Proteomics. 75, 18, p. 5749-61 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Total and cause-specific mortality by elevated transferrin saturation and hemochromatosis genotype in individuals with diabetes - two general population studies

      Ellervik, Christina, Mandrup-Poulsen, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 15 Oct 2013, In: Diabetes Care. 37, 2, p. 444-452 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Total mortality by elevated transferrin saturation in patients with diabetes

      Ellervik, Christina, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M. M., Birgens, H., Nordestgaard, Børge & Mandrup-Poulsen, Thomas, Sep 2013, In: Diabetes Care. 36, 9, p. 2646-54 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Elevated transferrin saturation and risk of diabetes: Three population-based studies

      Ellervik, Christina, Mandrup-Poulsen, Thomas, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M., Birgens, H. & Nordestgaard, Børge, 2011, In: Diabetes Care. 34, 10, p. 2256-8 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Response to Comment on: Ellervik et al. Elevated Transferrin Saturation and Risk of Diabetes: Three Population-Based Studies. Diabetes Care 2011;34:2256-2258

      Ellervik, Christina, Mandrup-Poulsen, Thomas, Birgens, H. & Nordestgaard, Børge, 2012, In: Diabetes Care. 35, 6, p. e48

      Research output: Contribution to journal › Journal article › Research

    14. Published

      Need for Reclassification of Diabetes Secondary to Iron Overload in the ADA and WHO Classifications

      Ellervik, Christina, Birgens, H. & Mandrup-Poulsen, Thomas, Jun 2014, In: Diabetes Care. 37, 6, p. e137-e138 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Targeting innate immune mediators in type 1 and type 2 diabetes

      Donath, M. Y., Dinarello, C. A. & Mandrup-Poulsen, Thomas, 2019, In: Nature Reviews. Immunology. 19, 12, p. 734-746

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      The use of interleukin-1-receptor antagonists in the treatment of diabetes mellitus.

      Donath, M. Y. & Mandrup-Poulsen, Thomas, 2008, In: Nature Clinical Practice Endocrinology & Metabolism. 4, 5, p. 240-1 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Cytokines and beta-cell biology: from concept to clinical translation

      Donath, M. Y., Storling, J., Berchtold, L. A., Billestrup, N. & Mandrup-Poulsen, Thomas, 2007, In: Endocrine Reviews. 29, 3, p. 334-50 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Role of IL-1beta in type 2 diabetes

      Dinarello, C. A., Donath, M. Y. & Mandrup-Poulsen, Thomas, 1 Aug 2010, In: Current Opinion in Endocrinology, Diabetes and Obesity. 17, 4, p. 314-21 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      IL-1 family nomenclature

      Dinarello, C., Arend, W., Sims, J., Smith, D., Blumberg, H., O'Neill, L., Goldbach-Mansky, R., Pizarro, T., Hoffman, H., Bufler, P., Nold, M., Ghezzi, P., Mantovani, A., Garlanda, C., Boraschi, D., Rubartelli, A., Netea, M., van der Meer, J., Joosten, L., Mandrup-Poulsen, T. & 14 others, Donath, M., Lewis, E., Pfeilschifter, J., Martin, M., Kracht, M., Muehl, H., Novick, D., Lukic, M., Conti, B., Solinger, A., Kelk, P., Peyman, K., van de Veerdonk, F. & Gabel, C., 1 Nov 2010, In: Nature Immunology. 11, 11, p. 973 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The lysine deacetylase inhibitor givinostat inhibits ß-cell IL-1ß induced IL-1ß transcription and processing

      Dahllöf, M. S., Christensen, D. P., Lundh, M., Dinarello, C. A., Mascagni, P., Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Nov 2012, In: Islets. 4, 6, p. 417-22 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      HDAC Inhibitor-Mediated Beta-Cell Protection Against Cytokine-Induced Toxicity Is STAT1 Tyr701 Phosphorylation Independent

      Dahllöf, M. S., Christensen, D. P., Harving, M., Wagner, B. K., Mandrup-Poulsen, Thomas & Lundh, M., 13 Jan 2015, In: Journal of Interferon & Cytokine Research. 35, 1, p. 63-70 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in beta-Cells

      Dahlby, T., Simon, C., Backe, M. B., Dahllof, M. S., Holson, E., Wagner, B. K., Boni-Schnetzler, M., Marzec, Michal Tomasz, Lundh, M. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences. 21, 21, 18 p., 8016.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Poor pregnancy outcome in women with type 2 diabetes

      Clausen, Tine Dalsgaard, Mathiesen, E., Ekbom, P., Hellmuth, E., Mandrup-Poulsen, Thomas & Damm, Peter, 2005, In: Diabetes Care. 28, 2, p. 323-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

      Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

      Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, Mandrup-Poulsen, Thomas, 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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