Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- Published
The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest
Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study
Alexiadou, K., Cuenco, J., Howard, J., Albrechtsen, Nicolai Jacob Wewer, Ilesanmi, I., Kamocka, A., Tharakan, G., Behary, P., Bech, P. R., Ahmed, A. R., Purkayastha, S., Wheller, R., Fleuret, M., Holst, Jens Juul, Bloom, S. R., Khoo, B. & Tan, T. M. M., 2020, In: B M J Open Diabetes Research & Care. 8, 1, 10 p., e001076.Research output: Contribution to journal › Review › Research › peer-review
- Published
Stability of glucagon-like peptide-1 and glucagon in human plasma
Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting the intestinal L-cell for obesity and type 2 diabetes treatment
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
Albrechtsen, Nicolai Jacob Wewer, Albrechtsen, Reidar, Bremholm, L., Svendsen, B., Kuhre, Rune Ehrenreich, Poulsen, Steen Seier, Christiansen, Charlotte Bayer, Jensen, E. P., Janus, C., Hilsted, Linda, Deacon, Carolyn F., Hartmann, Bolette & Holst, Jens Juul, 2016, In: Cell Reports. 17, 11, p. 2845-2856 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Toräng, S. & Holst, Jens Juul, 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?
Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and GLP-1 after oral glucose in postmenopausal women with impaired glucose tolerance.
Ahrén, B., Larsson, H. & Holst, Jens Juul, 1997, In: European Journal of Endocrinology. 137, p. 127-131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetogenic action of cholecystokinin in type 2 diabetes
Ahrén, B., Holst, Jens Juul & Efendic, S., 2000, In: J. Clin. Endocrinol. Metab.. 85, p. 1043-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia
Ahrén, B. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 1030-1038Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans
Ahrén, B., Holst, Jens Juul & Mari, A., Oct 2003, In: Diabetes Care. Supplement. 26, 10, p. 2860-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved glucagon tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice
Ahrén, B., Holst, Jens Juul, Mårtensson, H. & Balkan, B., 2000, In: Eur. J. Pharmacol.. 404, p. 239-245Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in non-insulin dependent diabetes mellitus.
Ahrén, B., Larsson, H. & Holst, Jens Juul, 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 473-478Research output: Contribution to journal › Journal article › Research › peer-review
- Published
1,5-Anhydro fructose increase glucose tolerance by increasing GLP-1 and insulin in mice
Ahrén, B., Holst, Jens Juul, Marcussen, J. & Yu, S., 2000, In: Eur. J. Pharmacol.. 397, p. 219-225Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1
Ahrén, B., Adner, N., Svartberg, J., Petrella, E., Holst, Jens Juul & Gutniak, M. K., Sep 2002, In: Diabetic Medicine. 19, 9, p. 790-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of Glycomacropeptide with Phenylalanine Free-Synthetic Amino Acids in Test Meals to PKU Patients: No Significant Differences in Biomarkers, Including Plasma Phe Levels
Ahring, K. K., Lund, A. M., Jensen, E., Jensen, T. G., Brondum-Nielsen, K., Pedersen, M., Bardow, A., Holst, Jens Juul, Rehfeld, Jens Frederik & Moller, L. B., 2018, In: Journal of Nutrition and Metabolism. 2018, p. 1-11 6352919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of GLP-1 effects on beta cell function after meal ingestion in humans
Ahren, B., Holst, Jens Juul & Mari, A., 2003, In: Diabetes Care. 26, p. 2860-2864Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs
Ahnfeldt, Agnethe May, Bæk, Ole, Hui, Y., Nielsen, Charlotte Holme, Obelitz-Ryom, K., Busk-Anderson, T., Ruge, A., Holst, Jens Juul, Rudloff, S., Burrin, D., Nguyen, Duc Ninh, Nielsen, Dennis Sandris, Zachariassen, G., Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2020, In: The Journal of Nutrition. 150, 5, p. 1196-1207Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets
Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, Jens Juul, Reimann, F. & Gribble, F. M., Oct 2016, In: Diabetologia. 59, 10, p. 2156-2165 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a Lifestyle Intervention on Bone Turnover in Persons with Type 2 Diabetes: A post hoc Analysis of the U-TURN Trial
Abildgaard, J., Johansen, M. Y., Skov-Jeppesen, Kirsa, Andersen, L. B., Karstoft, K., Hansen, K. B., Hartmann, Bolette, Holst, Jens Juul, Pedersen, Bente Klarlund & Ried-Larsen, M., 2022, In: Medicine and Science in Sports and Exercise. 54, 1, p. 38-46Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved postprandial suppression of bone turnover markers, despite increased fasting levels, in postmenopausal women
Abildgaard, J., Ploug, Thorkil, Pedersen, Anette Tønnes, Eiken, P., Pedersen, Bente Klarlund, Holst, Jens Juul, Hartmann, Bolette & Lindegaard, Birgitte, 2021, In: Bone. 143, 8 p., 115612.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors
Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial
Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S. & Krarup, T. M., 1 Apr 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-33 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway
't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, , 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo efficacy of HD0471953: A novel GPR119 agonist for the treatment of type 2 diabetes mellitus
'T Hart, L. M., Fritsche, A., Nijpels, G., Van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N., Van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., MacHicao, F. & 14 others, , 1 Feb 2015, In: Diabetes Technology & Therapeutics. 17, p. S131-S133Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs
Barkholt, P., Vegge, A., Clausen, T. R., Birck, M. M., Fels, J. J., Støckel, M., Gögenur, Ismail, Eriksen, Thomas, Holst, Jens Juul, Hansen, Axel Kornerup, Thymann, Thomas, Jelsing, J., Sangild, Per Torp & Raun, K., 2015, In: Journal of Obesity and Bariatrics. 1, 1, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
Most downloads
-
4124
downloads
Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2905
downloads
Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
690
downloads
Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
Research output: Contribution to journal › Journal article › Research › peer-review
Published