Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor


  1. Published

    Interaction Between Dietary Iron Intake and Genetically Determined Iron Overload: Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in the TEDDY Study

    Ullitz Thorsen, S., Liu, X., Kataria, Y., Mandrup-poulsen, T., Kaur, S., Uusitalo, U., Virtanen, S. M., Norris, J., Rewers, M., Hagopian, W., Yang, J., She, J., Akolkar, B., Rich, S. S., Aronsson, C. A., Lernmark, Å., Ziegler, A., Toppari, J., Krischer, J. P., Parikh, H. M. & 31 others, Ellervik, Christina, Svensson, Jannet, Rewers, M., Barbour, A., Bautista, K., Baxter, J., Felipe-morales, D., Frohnert, B. I., Stahl, M., Gesualdo, P., Hoffman, M., Karban, R., Liu, E., Munoz, A., Norris, J., O’donnell, H., Peacock, S., Shorrosh, H., Steck, A., Stern, M., Waugh, K., Toppari, J., Simell, O. G., Adamsson, A., Ahonen, S., Åkerlund, M., Anttila, S., Hakola, L., Hekkala, A., Agardh, D. & Environmental Determinants of Diabetes in the Young (TEDDY) Group, E. D. O. D. I. T. Y. (. G., 2023, In: Diabetes Care. 46, 5, p. 1-5

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans

    Spinas, G. A., Hansen, B. S., Linde, S., Kastern, W., Mølvig, J., Mandrup-Poulsen, Thomas, Dinarello, C. A., Nerup, J. & Nielsen, Jens Høiriis, Jul 1987, In: Diabetologia. 30, 7, p. 474-80 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Interleukin-1 antagonism: a sturdy companion for immune tolerance induction in type 1 diabetes?

    Mandrup-Poulsen, Thomas, Jun 2014, In: Diabetes. 63, 6, p. 1833-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

    Moran, A., Bundy, B., Becker, D. J., DiMeglio, L. A., Gitelman, S. E., Goland, R., Greenbaum, C. J., Herold, K. C., Marks, J. B., Raskin, P., Sanda, S., Schatz, D., Wherrett, D. K., Wilson, D. M., Krischer, J. P., Skyler, J. S., Pickersgill, L., de Koning, E., Ziegler, A-G., Böehm, B. & 12 others, Badenhoop, K., Schloot, N., Bak, J. F., Pozzilli, P., Mauricio, D., Donath, M. Y., Castaño, L., Wägner, A., Lervang, H. H., Perrild, Hans, Mandrup-Poulsen, Thomas & Type 1 Diabetes TrialNet Canakinumab Study Group, T. 1. D. T. C. S. G., 1 Jun 2013, In: Lancet. 381, 9881, p. 1905-15 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset

    Cabrera, S. M., Wang, X., Chen, Y., Jia, S., Kaldunski, M. L., Greenbaum, C. J., Mandrup-Poulsen, Thomas & Hessner, M. J., Apr 2016, In: European Journal of Immunology. 46, 4, p. 1030-1046 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Interleukin-1 antagonists and other cytokine blockade strategies for type 1 diabetes

    Mandrup-Poulsen, Thomas, 2012, In: The review of diabetic studies : RDS. 9, 4, p. 338-47 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Interleukin-1 antagonists for diabetes

    Mandrup-Poulsen, Thomas & AIDA study group, A. S. G., Aug 2013, In: Expert Opinion on Investigational Drugs. 22, 8, p. 965-79 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine

    Andersen, H. U., Mauricio, D., Karlsen, A. E., Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, Feb 1996, In: European Journal of Endocrinology. 134, 2, p. 251-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Interleukin-1 receptorantagonistbehandling af patienter med type 2-diabetes--sekundaerpublikation.

    Larsen, C. M., Faulenbach, M., Vaag, Allan, Vølund, A., Ehses, J., Seifert, B., Mandrup-Poulsen, Thomas & Donath, M., 2007, In: Ugeskrift for læger. 169, 45, p. 3868-71 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Interleukin-1-receptor antagonist in type 2 diabetes mellitus - Reply

    Mandrup-Poulsen, Thomas, Seifert, B. & Donath, M. Y., 2007, In: New England Journal of Medicine. 357, 3, p. 303-303

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Interleukin-1-receptor antagonist in type 2 diabetes mellitus.

    Larsen, C. M., Faulenbach, M., Vaag, Allan, Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, Thomas & Donath, M. Y., 2007, In: New England Journal of Medicine. 356, 15, p. 1517-26 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

    Ballak, D. B., Li, S., Cavalli, G., Stahl, J. L., Tengesdal, I. W., van Diepen, J. A., Kluck, V., Swartzwelter, B., Azam, T., Tack, C. J., Stienstra, R., Mandrup-Poulsen, Thomas, Seals, D. R. & Dinarello, C. A., 2018, In: Journal of Biological Chemistry. 293, 37, p. 14224-14236

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Interleukin-6 and diabetes: the good, the bad, or the indifferent?

    Kristiansen, O. P. & Mandrup-Poulsen, Thomas, 2005, In: Diabetes. 54 Suppl 2, p. S114-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Interleukin-6 receptor blockade or TNF alpha inhibition for reducing glycaemia in patients with RA and diabetes: post hoc analyses of three randomised, controlled trials

    Genovese, M. C., Burmester, G. R., Hagino, O., Thangavelu, K., Iglesias-Rodriguez, M., John, G. S., Gonzalez-Gay, M. A., Mandrup-Poulsen, Thomas & Fleischmann, R., 2020, In: Arthritis Research & Therapy. 22, 1, 12 p., 206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Iron: the hard player in diabetes pathophysiology

    Hansen, J. B., Moen, I. W. & Mandrup-Poulsen, Thomas, Apr 2014, In: Acta Physiologica (Print). 210, 4, p. 717-32 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Iron Regulation of Pancreatic Beta-Cell Functions and Oxidative Stress

    Backe, M. B., Moen, I. W., Ellervik, Christina, Hansen, J. B. & Mandrup-Poulsen, Thomas, 17 Jul 2016, In: Annual Review of Nutrition. 36, p. 241-273 33 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Iron Status and Gestational Diabetes: A Meta-Analysis

    Kataria, Y., Wu, Y., Horskjaer, P. D. H., Mandrup-Poulsen, Thomas & Ellervik, Christina, 2018, In: Nutrients. 10, 5, 15 p., 621 .

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Is puberty an accelerator of type 1 diabetes in IL6-174CC females?

    Gillespie, K. M., Nolsøe, R., Betin, V. M., Kristiansen, O. P., Bingley, P. J., Mandrup-Poulsen, Thomas & Gale, E. A. M., 2005, In: Diabetes. 54, 4, p. 1245-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

    Mandrup-Poulsen, Thomas, Spinas, G. A., Prowse, S. J., Hansen, B. S., Jørgensen, D. W., Bendtzen, K., Nerup, J. & Nielsen, Jens Høiriis, May 1987, In: Diabetes. 36, 5, p. 641-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression

    Prause, Michala Cecilie Burstein, Mayer, C. M., Brorsson, C., Frederiksen, K. S., Billestrup, Nils, Størling, Joachim & Mandrup-Poulsen, Thomas, 2016, In: Journal of Diabetes Research. 2016, 15 p., 1312705.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis

    Prause, Michala Cecilie Burstein, Christensen, D. P., Billestrup, Nils & Mandrup-Poulsen, Thomas, 2014, In: PLOS ONE. 9, 1, p. 1-11 11 p., e87067.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Large-scale prospective T cell function assays in shipped, unfrozen blood samples: experiences from the multicenter TRIGR trial

    Hadley, D., Cheung, R. K., Becker, D. J., Girgis, R., Palmer, J. P., Cuthbertson, D., Krischer, J. P., Dosch, H., TRIGR North America Investigators, T. N. A. I. & Mandrup-Poulsen, Thomas, Feb 2014, In: Clinical and Vaccine Immunology (Online). 21, 2, p. 203-11 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients

    Østergaard, H. B., Mandrup-Poulsen, Thomas, Berkelmans, G. F. N., van der Graaf, Y., Visseren, F. L. J. & Westerink, J., 2019, In: Diabetes and Metabolism. 45, 3, p. 254-260 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Lost in translation

    Frank, L. & Mandrup-Poulsen, Thomas, 2007, In: Weekendavisen. 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

    Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, Mandrup-Poulsen, Thomas, 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 923693