Jens Juul Holst

Jens Juul Holst

Professor


  1. 2011
  2. Published

    Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial

    Raben, Anne, Møller, B. K., Flint, A., Vasilaris, T. H., Møller, A. C., Holst, Jens Juul & Astrup, A., 2011, In: Food & Nutrition Research. 55, 5961, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes

    Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Inkretiner

    Vilsbøll, Tina & Holst, Jens Juul, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2 ed. København: Munksgaard , p. 67-74 8 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  5. Published

    Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion

    Witte, A., Grybäck, P., Jacobsson, H., Näslund, E., Hellström, P. M., Holst, Jens Juul, Hilsted, Linda & Schmidt, P. T., 2011, In: Scandinavian Journal of Gastroenterology. Supplement. 46, 4, p. 428-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials

    Buse, J. B., Garber, A., Rosenstock, J., Schmidt, W. E., Brett, J. H., Videbæk, N., Holst, Jens Juul & Nauck, M., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 6, p. 1695-702 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Lixisenatide for type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test

    Møller, J. B., Jusko, W. J., Gao, W., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Overgaard, R. V., Madsen, H. & Ingwersen, S. H., 2011, In: Journal of Pharmacokinetics and Pharmacodynamics. 38, 6, p. 713-25 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Neuroprotective properties of GLP-1: theoretical and practical applications

    Holst, Jens Juul, Burcelin, R. & Nathanson, E., 2011, In: Current Medical Research and Opinion. 27, 3, p. 547-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential

    Torekov, Signe Sørensen, Madsbad, Sten & Holst, Jens Juul, 2011, In: Obesity Reviews. 12, 8, p. 593-601 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Protein dose-response effect on glp-1, pyy and appetite in male subjects

    Sparre, A. B., Sørensen, M. Q., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2011, In: Obesity Reviews. 12, suppl. 1, p. 59 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  12. Published

    Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans

    Nauck, M. A., Kemmeries, G., Holst, Jens Juul & Meier, J. J., 2011, In: Diabetes. 60, 5, p. 1561-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?

    Nauck, M. A., Vardarli, I., Deacon, Carolyn F., Holst, Jens Juul & Meier, J., 2011, In: Diabetologia. 54, 1, p. 10-18 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

    Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys

    Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans

    Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

    Lund, Asger Bach, Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 6, p. E1038-E1046 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia?

    Hansen, A. M. K., Bödvarsdottir, T. B., Nordestgaard, D. N. E., Heller, Rasmus, Gotfredsen, C. F., Maedler, K., Fels, J., Holst, Jens Juul & Karlsen, A., 2011, In: Diabetologia. 54, 6, p. 1379-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal

    Naessén, S., Carlström, K., Holst, Jens Juul, Hellström, P. M. & Hirschberg, A. L., 2011, In: American Journal of Clinical Nutrition. 94, 4, p. 967-972 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

    Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, N., Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status

    Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men

    Nathanson, D., Zethelius, B., Berne, C., Lind, L., Andrén, B., Ingelsson, E., Holst, Jens Juul & Nyström, T., Mar 2011, In: Diabetic Medicine. 28, 3, p. 301-305 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats

    Thomsen, K., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul, Jessen, N., Frystyk, J. & Vilstrup, H., Apr 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 2, p. 150-156 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4

    Hansen, M., Knop, Filip Krag & Holst, Jens Juul, Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future

    Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function

    Kielgast, U., Holst, Jens Juul & Madsbad, Sten, May 2011, In: Diabetes. 60, 5, p. 1599-1607 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes

    Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors

    Hansen, M., Juul Hare, K., Holst, Jens Juul & Knop, Filip Krag, Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    KU bestemmer selv over sin forskning

    Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.

    Research output: Contribution to journalContribution to newspaper - Comment/debateCommunication

  30. Published

    Dissociated incretin hormone response to protein versus fat ingestion in obese subjects

    Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function

    Kielgast, U., Krarup, T., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jul 2011, In: Diabetes Care. 34, 7, p. 1463-1468 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients

    Samocha-Bonet, D., Wong, O., Synnott, E., Piyaratna, N., Douglas, A., Gribble, F. M., Holst, Jens Juul, Chisholm, D. J. & Greenfield, J. R., Jul 2011, In: Journal of Nutrition. 141, 7, p. 1233-1238 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Administration of a dipeptidyl peptidase IV inhibitor enhances the intestinal adaptation in a mouse model of short bowel syndrome

    Okawada, M., Holst, Jens Juul & Teitelbaum, D. H., Aug 2011, In: Surgery. 150, 2, p. 217-223 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans

    Lindgren, O., Carr, R. D., Deacon, Carolyn F., Holst, Jens Juul, Pacini, G., Mari, A. & Ahrén, B., Aug 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 8, p. 2519-2524 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes

    Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice

    Waget, A., Cabou, C., Masseboeuf, M., Cattan, P., Armanet, M., Karaca, M., Castel, J., Garret, C., Payros, G., Maida, A., Sulpice, T., Holst, Jens Juul, Drucker, D. J., Magnan, C. & Burcelin, R., Aug 2011, In: Endocrinology. 152, 8, p. 3018-3029 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Gastric emptying, glucose metabolism and gut hormones: evaluation of a common preoperative carbohydrate beverage

    Vermeulen, M. A. R., Richir, M. C., Garretsen, M. K., van Schie, A., Ghatei, M. A., Holst, Jens Juul, Heijboer, A. C., Uitdehaag, B. M. J., Diamant, M., Eekhoff, E. M. W., van Leeuwen, P. A. M. & Ligthart-Melis, G. C., Sep 2011, In: Nutrition. 27, 9, p. 897-903 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1

    Holst, Jens Juul, Sep 2011, In: Diabetes. 60, 9, p. 2203-2205 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Foetal proglucagon processing in relation to adult appetite control: lessons from a transplantable rat glucagonoma with severe anorexia

    Jensen, P. B., Larsen, P. J., Karlsen, C., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl. 1, p. 60-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Regulation of glucagon secretion by incretins

    Holst, Jens Juul, Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. & Knop, Filip Krag, Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl 1, p. 89-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium

    Tam, C. S., Berthoud, H., Bueter, M., Chakravarthy, M. V., Geliebter, A., Hajnal, A., Holst, Jens Juul, Kaplan, L., Pories, W., Raybould, H., Seeley, R., Strader, A. & Ravussin, E., Nov 2011, In: Obesity Reviews. 12, 11, p. 984-94 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Effect of method of delivery of sodium butyrate on rumen development in newborn calves

    Górka, P., Kowalski, Z. M., Pietrzak, P., Kotunia, A., Jagusiak, W., Holst, Jens Juul, Guilloteau, P. & Zabielski, R., Nov 2011, In: Journal of Dairy Science. 94, 11, p. 5578-88 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus

    Stephens, J. W., Bodvarsdottir, T. B., Wareham, K., Prior, S. L., Bracken, R. M., Lowe, G. D., Rumley, A., Dunseath, G., Luzio, S., Deacon, Carolyn F., Holst, Jens Juul & Bain, S. C., Nov 2011, In: Diabetes Research and Clinical Practice. 94, 2, p. 199-206 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Glucagon antagonism as a potential therapeutic target in type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain

    Ugleholdt, Randi Kjærsgaard, Pedersen, Jens, Bassi, Maria Rosaria, Füchtbauer, E., Jørgensen, S. M., Kissow, Hannelouise, Nytofte, N., Poulsen, Steen Seier, Rosenkilde, Mette, Seino, Y., Thams, P., Holst, Peter Johannes & Holst, Jens Juul, Dec 2011, In: The Journal of Biological Chemistry. 286, 52, p. 44632-44645 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2012
  47. Published

    Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance

    Jørgensen, N. B., Jacobsen, S. H., Dirksen, C., Bojsen-Møller, K. N., Naver, L., Hvolris, L., Clausen, T. R., Wulff, B. S., Worm, Dorte, Lindqvist Hansen, D., Madsbad, Sten & Holst, Jens Juul, 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 1, p. E122-31

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects

    Holmer-Jensen, J., Hartvigsen, M., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, p. 32-38 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Alcohol intake and its effect on some appetite-regulating hormones in man: influence of gastroprotection with sucralfate

    Calissendorff, J., Gustafsson, T., Holst, Jens Juul, Brismar, K. & Röjdmark, S., 2012, In: Endocrine Research. 37, 3, p. 154-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects

    Jacobsen, S. H., Olesen, S. C., Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Worm, Dorte, Almdal, Thomas Peter, Naver, L. S., Hvolris, L. E., Rehfeld, Jens Frederik, Wulff, B. S., Clausen, T. R., Hansen, D. L., Holst, Jens Juul & Madsbad, Sten, 2012, In: Obesity Surgery. 22, 7, p. 1084-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes

    Mortensen, L. S., Holmer-Jensen, J., Hartvigsen, M., Jensen, V. K., Astrup, A., Vrese, M. D., Holst, Jens Juul, Thomsen, C. H. P. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, 7, p. 799-805 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Effects of everyday life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes: collection of clinical data for glucose modeling

    Schmidt, S. D., Finan, D. A., Duun-Henriksen, A. K., Jørgensen, J. B., Madsen, H., Bengtsson, H., Holst, Jens Juul, Madsbad, S. & Nørgaard, K., 2012, In: Diabetes Technology & Therapeutics. 14, 3, p. 210-217 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207