Nils Billestrup

Nils Billestrup

Professor

Member of:

    ORCID: 0000-0002-4968-8067

    Publication year:
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    101 - 118 out of 118Page size: 100
    1. 2015
    2. Published

      Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents

      Christensen, G. L., Jacobsen, M. L. B., Wendt, A., Mollet, I. G., Friberg, J., Frederiksen, K. S., Meyer, M., Bruun, C., Eliasson, L. & Billestrup, Nils, Jun 2015, In: Diabetologia. 58, 6, p. 1282-1290 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Surface-expressed insulin receptors as well as IGF-I receptors both contribute to the mitogenic effects of human insulin and its analogues

      Lundby, A., Bolvig, P., Hegelund, A. C., Hansen, B. F., Worm, J., Lützen, A., Billestrup, Nils, Bonnesen, C. & Oleksiewicz, M. B., Jul 2015, In: Journal of Applied Toxicology. 35, 7, p. 842-850 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The Anti-diabetic Effects of GLP-1-gastrin Dual Agonist ZP3022 in ZDF rats

      Skarbaliene, J., Secher, T., Jelsing, J., Ansarullah, Neerup, T. S. R., Billestrup, Nils & Fosgerau, K., Jul 2015, In: Peptides. 69, p. 47-55 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 2016
    6. Published

      JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression

      Prause, Michala Cecilie Burstein, Mayer, C. M., Brorsson, C., Frederiksen, K. S., Billestrup, Nils, Størling, Joachim & Mandrup-Poulsen, Thomas, 2016, In: Journal of Diabetes Research. 2016, 15 p., 1312705.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Inflammatory Cytokines Stimulate Bone Morphogenetic Protein-2 Expression and Release from Pancreatic Beta Cells

      Urizar, A. I., Friberg, J., Christensen, D. P., Christensen, G. L. & Billestrup, Nils, 1 Jan 2016, In: Journal of Interferon & Cytokine Research. 36, 1, p. 20-29

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells

      Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Aberrant accumulation of the diabetes autoantigen GAD65 in Golgi membranes in conditions of ER stress and autoimmunity

      Phelps, E. A., Cianciaruso, C., Michael, I. P., Pasquier, M., Kanaani, J., Nano, R., Lavallard, V., Billestrup, Nils, Hubbell, J. A. & Baekkeskov, S., Sep 2016, In: Diabetes. 65, 9, p. 2686-2699

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.

      Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro

      Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. 2017
    13. Published

      Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

      Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes

      Skarbaliene, J., Rigbolt, K. T., Fosgerau, K. & Billestrup, Nils, 15 Nov 2017, In: European Journal of Pharmacology. 815, p. 181-189 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2018
    16. Published

      Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics)

      Kang, T., Jensen, P., Huang, H., Lund Christensen, G., Billestrup, Nils & Larsen, M. R., Jan 2018, In: Molecular and Cellular Proteomics. 17, 1, p. 95-110 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. 2019
    18. Published

      Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1 beta is associated with changes in expression of beta-cell maturity genes and associated histone modifications

      Urizar, A. I., Prause, Michala Cecilie Burstein, Wortham, M., Sui, Y., Thams, P., Sander, M., Christensen, G. L. & Billestrup, Nils, 2019, In: Molecular and Cellular Endocrinology. 496, 12 p., 110524 .

      Research output: Contribution to journal › Review › Research › peer-review

    19. 2021
    20. Published

      Butyrate protects pancreatic beta cells from cytokine-induced dysfunction

      Prause, Michala Cecilie Burstein, Pedersen, Signe Schultz, Tsonkova, V., Qiao, M. & Billestrup, Nils, 2021, In: International Journal of Molecular Sciences. 22, 19, 18 p., 10427.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. 2022
    22. Published

      Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

      Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. 2023
    24. Published

      Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

      Urizar, A. I., Prause, Michala Cecilie Burstein, Ingerslev, L. R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, Romain, Larsen, M. R., Christensen, G. L. & Billestrup, Nils, 2023, In: Cell Death and Disease. 14, 7, 16 p., 399.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

      Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 2024
    27. Published

      Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction

      Pedersen, Signe Schultz, Ingerslev, Lars Roed, Olsen, M., Prause, Michala Cecilie Burstein & Billestrup, Nils, 2024, In: FEBS Journal. 291, 3, p. 566-583

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 15311848