Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Acute effects of continuous infusions of glucagon-like peptide (GLP)-1, GLP-2 and the combination (GLP-1+GLP-2) on intestinal absorption in short bowel syndrome (SBS) patients. A placebo-controlled study

    Madsen, K. B., Askov-Hansen, C., Naimi, R. M., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 30-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable alpha- and beta-cell tumor phenotypes

    Madsen, O. D., Karlsen, C., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, Jens Frederik, Larsson, L. I., Steiner, D. F. & Holst, Jens Juul, Nov 1993, In: Endocrinology. 133, 5, p. 2022-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable *Ga- and *Gb-cell tumor phenotypes

    Madsen, O. D., Karlsen, G., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, J. F., Larsson, L., Steiner, D. F., Holst, Jens Juul & Michelsen, B. K., 1993, In: Endokrinologiya. vol. 133, no. 5, p. 2022-2030

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia

    Madsen, O. D., Karlsen, C., Blume, N., Jensen, H. I., Larsson, L. & Holst, Jens Juul, 1995, In: Scand. J. Clin. Lab. Invest.. 55, suppl. 220, p. 27-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Advances in non-peptide glucagon receptor antagonist

    Madsen, P., Knudsen, L. B., Brand, C. L. & Holst, Jens Juul, 1999, In: Curr. Pharm Design. 5, p. 683-691

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Unravelling Effects of Rosemary (Rosmarinus officinalis L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet

    Madsen, S., Bak, S. Y., Yde, C. C., Jensen, H. M., Knudsen, T. A., Bæch-Laursen, C., Holst, Jens Juul, Laustsen, C. & Hedemann, M. S., 2023, In: Metabolites. 13, 9, 21 p., 974.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles

    Madsen, Thomas Daugbjerg, Hansen, L. H., Hintze, John, Ye, Z., Jebari, S., Andersen, Daniel Bjørklund, Joshi, Hiren Jitendra, Ju, T., Goetze, Jens P. , Martin, C., Rosenkilde, Mette, Holst, Jens Juul, Kuhre, Rune Ehrenreich, Goth, C. K., Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2020, In: Nature Communications. 11, 1, 13 p., 4033.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol

    Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.

    Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

    Manell, E., Puuvuori, E., Svensson, A., Velikyan, I., Hulsart-Billström, G., Hedenqvist, P., Holst, Jens Juul, Jensen Waern, M. & Eriksson, O., 2021, In: B M J Open Diabetes Research & Care. 9, 10 p., e002083.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Impact of Synbiotic Intake on Liver Metabolism in Metabolically Healthy Participants and Its Potential Preventive Effect on Metabolic-Dysfunction-Associated Fatty Liver Disease (MAFLD): A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial

    Mantri, A., Köhlmoos, A., Schelski, D. S., Seel, W., Stoffel-Wagner, B., Krawitz, P., Stehle, P., Holst, Jens Juul, Weber, B., Koban, L., Plassmann, H. & Simon, M. C., 2024, In: Nutrients. 16, 9, 14 p., 1300.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes

    Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., Aug 2005, In: The Journal of clinical endocrinology and metabolism. 90, 8, p. 4888-94 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Vildagliptin, a dipeptidyl peptidase-IV inhibitor improves model-assessed beta-cell function in patients with type 2 diabetes

    Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Duning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 4888-4894

    Research output: Contribution to journalJournal articleResearch

  15. Published

    The incretin enhancer vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed -cell function in patients with type 2 diabetes

    Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, p. 4888-4894

    Research output: Contribution to journalJournal articleResearch

  16. Published

    Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes

    Mari, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2013, In: PLOS ONE. 8, 9, p. e73154

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women

    Mark, A. B., Poulsen, M. W., Andersen, S., Andersen, J. M., Bak, M. J., Ritz, C., Holst, Jens Juul, Nielsen, J., de Courten, B., Dragsted, Lars Ove & Bügel, Susanne Gjedsted, 2014, In: Diabetes Care. 37, 1, p. 88-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome

    Martin, G. R., Wallace, L. E., Hartmann, Bolette, Holst, Jens Juul, Demchyshyn, L., Toney, K. & Sigalet, D. L., Mar 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 288, 3, p. G431-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    High-Intensity Interval Training, Appetite, and Reward Value of Food in the Obese

    Martins, C., Aschehoug, I., Ludviksen, M., Holst, Jens Juul, Finlayson, G., Wisloff, U., Morgan, L., King, N. & Kulseng, B., Sep 2017, In: Medicine and Science in Sports and Exercise. 49, 9, p. 1851-1858 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effect of moderate- and high-intensity acute exercise on appetite in obese individuals

    Martins, C., Stensvold, D., Finlayson, G., Holst, Jens Juul, Wisloff, U., Kulseng, B., Morgan, L. & King, N. A., Jan 2015, In: Medicine and Science in Sports and Exercise. 47, 1, p. 40-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The effects of exercise-induced weight loss on appetite-related peptides and motivation to eat

    Martins, C., Kulseng, B., King, N. A., Holst, Jens Juul & Blundell, J. E., 1 Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1609-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    L cell secretory responses after gastric bypass surgery can be imitated in un-operated individuals by modulating carbohydrate digestion

    Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Svane, M. S., Holst, Jens Juul & Madsbad, Sten, 2018, In: Diabetologia. 61, S1, p. S124-S125 244.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Effect of macronutrient composition and energy content on post-prandial secretion of satiety hormones and next meal food intake

    Martinussen, C., Svane, M. S., Bojsen-Moller, K. N., Andersen, B. V., Hulme, O. J., Byrne, D. V., Siebner, Hartwig Roman, Hermansen, K., Gregersen, S., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 2020, In: Diabetologia. 63, SUPPL 1, p. S114-S115 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery

    Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Intestinal sensing and handling of dietary lipids in gastric bypass-operated patients and matched controls

    Martinussen, C., Dirksen, C., Bojsen-Møller, K. N., Svane, M. S., Carlsson, E. R., Hartmann, Bolette, Clausen, T. R., Veedfald, Simon, Kristiansen, V. B., Rehfeld, Jens Frederik, Hansen, Harald S., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Clinical Nutrition. 111, 1, p. 28-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass

    Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals

    Martinussen, C., Svane, M. S., Bojsen-Møller, K. N., Jensen, Christian Zinck, Kristiansen, V. B., Bookout, A. L., Jorgensen, S. B., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Madsbad, Sten & Kuhre, Rune Ehrenreich, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. p. E443-E452 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Augmented GLP-1 Secretion as Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion

    Martinussen, C., Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, Aug 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3233–3244

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Arginine-induced glucagon secretion and glucagon-induced enhancement of amino acid catabolism are not influenced by ambient glucose levels in mice

    Maruszczak, K., Rasmussen, C., Ceutz, F. R., Ørgaard, A., Elmelund, E., Richter, Michael Martin, Holst, Jens Juul, Winther-Sørensen, Marie & Albrechtsen, Nicolai Jacob Wewer, 2022, In: American Journal of Physiology - Endocrinology and Metabolism. 323, p. E207–E214

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect

    Mathiesen, D. S., Bagger, J., Hansen, K. B., Junker, A. E., Plamboeck, A., Harring, S., Idorn, T., Hornum, M., Holst, Jens Juul, Jonsson, Anna Elisabet, Hansen, Torben, Vilsbøll, Tina, Lund, Asger Bach & Knop, Filip Krag, 2020, In: Endocrine Connections. 9, 12, p. 1221-1232 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology

    Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men

    Matikainen, N., Söderlund, S., Björnson, E., Bogl, L. H., Pietiläinen, K. H., Hakkarainen, A., Lundbom, N., Eliasson, B., Räsänen, S. M., Rivellese, A., Patti, L., Prinster, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., Jun 2017, In: Nutrition, Metabolism & Cardiovascular Diseases. 27, 6, p. 534-542 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance

    Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men

    Matikainen, N., Björnson, E., Söderlund, S., Borén, C., Eliasson, B., Pietiläinen, K. H., Bogl, L. H., Hakkarainen, A., Lundbom, N., Rivellese, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., 2016, In: PLOS ONE. 11, 1, p. 1-15 15 p., e0145890.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

    McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-E1755

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

    McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., Dec 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Histochemical, pharmacological, biochemical and chromatographic evidence that pituitary adenylyl cyclase activating peptide is involved in inhibitory neurotransm.in the taenia of the guinea-pig caecum

    McConalogue, K., Furness, J. B., Vremec, M. A., Holst, Jens Juul, Tornøe, K. & Marley, P. D., 1995, In: J. Autonom Nerv. System. 50, p. 311-322

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Differential effects of bile acids on the postprandial secretion of gut hormones: A randomized crossover study

    McGlone, E. R., Malallah, K., Cuenco, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vincent, R. P., Ling, C., Khan, O. A., Verma, S., Ahmed, A. R., Walters, J. R. F., Khoo, B., Bloom, S. R. & Tan, T. M. M., 2021, In: American Journal of Physiology - Endocrinology and Metabolism. 320, 4, p. E671-E679

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Reversible hyperinsulinemic hypoglycemia after gastric bypass: a consequence of altered nutrient delivery

    McLaughlin, T., Peck, M., Holst, Jens Juul & Deacon, Carolyn F., Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1851-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

    Medici, B. R., Nygaard, Birte, la Cour, J. L., Krakauer, M., Brønden, Andreas, Sonne, M. P., Holst, Jens Juul, Rehfeld, Jens Frederik, Vilsbøll, Tina, Faber, J. & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 10, 14 p., e230314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

    Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans

    Meier, J. J., Gethmann, A., Götze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Mar 2006, In: Diabetologia. 49, 3, p. 452-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes

    Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2005, In: Diabetologia. 48, 9, p. 1872-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

    Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In: Diabetologia. 46, 6, p. 798-801 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Stimulation of glucagon secretion and inhibition of gastric acid secretion by glucagon-like peptide-2 (GLP-2) in healthy human subjects

    Meier, J., Nauck, M. A., Pott, A., Heinze, K., Götze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, p. 44-54

    Research output: Contribution to journalJournal articleResearch

  46. Published

    Insulinotropic effect of gastric inhibitory polypeptide (GIP) in women with a history of gestational diabetes

    Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2005, In: Diabetologia. 48, p. 1872-1881

    Research output: Contribution to journalJournal articleResearch

  47. Published

    Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects

    Meier, J. J., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Nauck, M. A., 2007, In: Diabetologia. 50, 4, p. 806-813 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes

    Meier, J. J., Huking, K., Holst, Jens Juul, Deacon, Carolyn F., Schmiegel, W. H. & Nauck, M. A., 2001, In: Diabetes. 50, p. 2497-2504

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Erythromycin antagonises the deceleration of gastric emptying by glucagon-like peptide-1 (GLP)-1 and unmasks its insulinotropic effect in healthy subjects

    Meier, J. J., Kemmeries, G., Holst, Jens Juul & Nauck, M. A., 2005, In: Diabetes. 54, p. 2212-2218

    Research output: Contribution to journalJournal articleResearch

  50. Published

    Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans

    Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 44-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207