Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy

    Andersen, O., Haugaard, S. B., Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, S., 2005, In: HIV Medicine. 6, p. 91-98

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Secretion of glucagon-like peptide-1 and reactive hypoglycemia after partial gastrectomy

    Andreasen, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Digestion. 55, p. 221-228

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Glucagon-like peptide-2 (GLP-2) response to enteral intake in children during anti-cancer treatment

    Andreassen, B. U., Paerregaard, A., Schmiegelow, Kjeld, Rechnitzer, C., Heilman, C., Hartmann, Bolette, Holst, Jens Juul & Michaelsen, Kim F., Jan 2005, In: Journal of Pediatric Gastroenterology and Nutrition. 40, 1, p. 48-53 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Glucagon-like-peptide-2 (GLP-2) response to enteral intake in children during anticancer treatment

    Andreassen, B. U., Pærregaard, A., Schmiegelow, K., Rechnitzer, C., Hartmann, B., Holst, Jens Juul & Michaelsen, K. F., 2005, In: Journal of Pediatric Gastroenterology and Nutrition. 40, p. 48-53

    Research output: Contribution to journal › Journal article › Research

  6. Published

    Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease

    Anholm, C., Kumarathurai, P., Jurs, A., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Holst, Jens Juul, Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetology & Metabolic Syndrome. 11, 12 p., 42.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?

    Arngrim, N., Simonsen, L., Holst, Jens Juul & Bülow, J., 2012, In: International Journal of Obesity. 37, p. 748-50

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise

    Ashcroft, Stephen Paul, Jepsen, Sara Lind, Ehrlich, Amy M, Treebak, Jonas Thue, Holst, Jens Juul & Zierath, Juleen R, 2023, In: STAR Protocols. 4, 1, 11 p., 101985.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure

    Askov-Hansen, C., Jeppesen, Palle Bekker, Lund, P., Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 10 Feb 2013, In: Regulatory Peptides. 181, p. 4-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man

    Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Jensen, B. L., Holst, Jens Juul & Bülow, J., Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2509–2519

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy

    Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Sorensen, Charlotte Mehlin, Jonassen, Thomas & Bulow, J., May 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 9, p. E744-E753 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Renal Extraction and Acute Effects of Glucagon-like peptide-1 on Central and Renal Hemodynamics in Healthy Men

    Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Jonassen, Thomas & Bülow, J., 15 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 8, p. E641-E649 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men

    Asmar, A., Asmar, M., Simonsen, L., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette, Sorensen, Charlotte Mehlin & Bülow, J., Feb 2017, In: Physiological Reports. 5, 3, 12 p., e13073.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The Renal Extraction and the Natriuretic Action of GLP-1 in Humans Depend on Interaction With the GLP-1 Receptor

    Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Hartmann, Bolette, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. e11-e19 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Increased oral sodium chloride intake in humans amplifies selectively postprandial GLP-1 but not GIP, CCK, and gastrin in plasma

    Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2020, In: Physiological Reports. 8, 15, 11 p., e14519.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects

    Asmar, M., Simonsen, L., Arngrim, N., Holst, Jens Juul, Dela, Flemming & Bülow, J., 2013, In: International journal of obesity (2005). 38, 2, p. 259-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss

    Asmar, M., Arngrim, N., Simonsen, L., Asmar, A., Nordby, P., Holst, Jens Juul & Bülow, J., 2016, In: Nutrition and Diabetes. 6, 7 p., e208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans

    Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    GIP-induced vasodilation in human adipose tissue involves capillary recruitment

    Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans

    Asmar, M., Simonsen, L., rck626, rck626, Holst, Jens Juul, Dela, Flemming & Bülow, J., Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3155-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor

    Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    RETRACTION: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries (Retraction of Vol 104, Pg 16, 2019)

    Asmar, M., Asmar, A., Simonsen, L., Holst, Jens Juul & Bulow, J., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 1, p. W1-W9

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances

    Asmar, M. & Holst, Jens Juul, 1 Feb 2010, In: Current Opinion in Endocrinology, Diabetes and Obesity. 17, 1, p. 57-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

    Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans

    Asmar, M., Simonsen, L., Madsbad, Sten, Stallknecht, Bente Merete, Holst, Jens Juul & Bülow, J., 1 Sep 2010, In: Diabetes. 59, 9, p. 2160-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery

    Aukan, M. I., Skårvold, S., Brandsaeter, I. Ø., Rehfeld, Jens Frederik, Holst, Jens Juul, Nymo, S., Coutinho, S. & Martins, C., 2023, In: Obesity. 31, 2, p. 399-411 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade

    Aulinger, B. A., Bedorf, A., Kutscherauer, G., de Heer, J., Holst, Jens Juul, Göke, B. & Schirra, J., Mar 2014, In: Diabetes. 63, 3, p. 1079-92 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus.

    Azuma, K., Radikova, Z., Mancino, J., Toledo, F., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D. & Kelley, D., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, p. 459-463

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes

    Azuma, K., Rádiková, Z., Mancino, J., Toledo, F. G. S., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D., Foley, J. E. & Kelley, D. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 459-464 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Functional Magnetic Resonance Imaging (fMRI) of Neural Responses to Visual and Auditory Food Stimuli Pre and Post Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG)

    Baboumian, S., Pantazatos, S. P., Kothari, S., McGinty, J., Holst, Jens Juul & Geliebter, A., 2019, In: Neuroscience. 409, p. 290-298

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Gut-derived glucagon in man: [Meeting Abstract]

    Baekdal, M., Lund, A., Albrechtsen, Nicolai Jacob Wewer, Egholk, J., Jorsal, T., Black-Juel, C. T., Dal, Jenna Elizabeth Hunt, Galsgaard, Katrine Douglas, Rigbolt, K., Palnaes, C., Ørskov, Cathrine, Poulsen, Steen Seier, Holst, Jens Juul, Villsboll, T. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 472.

    Research output: Contribution to journal › Conference abstract in journal › Research

  34. Published

    Counterregulatory responses to hypoglycaemia in totally pancreatectomised patients

    Baekdal, M., Lund, A., Baldassare, M. P. A., Rose, K., Egholk, J., Christensen, M. B., Hansen, C. P., Storkholm, J. H., Faber, Jens, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S95-S95

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  35. Published

    Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

    Baekdal, M., Nielsen, S. W., Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2024, In: Diabetes Care. 47, 1, p. 71-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Glucagon antagonism as a potential therapeutic target in type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young

    Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Increased liver fat content in totally pancreatectomised patients

    Bagger, J. I., Lund, A. B., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M. F., Hansen, C. P., Storkholm, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, S1, p. S572-S573

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  39. Published

    Impaired regulation of the incretin effect in patients with type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, drb459, drb459, Holst, Jens Juul & Vilsbøll, Tina, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure

    Bagger, J. I., Holst, Jens Juul, Hartmann, Bolette, Andersen, B., Knop, Filip Krag & Vilsbøll, T., 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 12, p. 4541–4552 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Glucagonostatic Potency of GLP-1 in Patients with Type 2 Diabetes, in Patients with Type 1 Diabetes, and Healthy Control Subjects

    Bagger, J. I., Grøndahl, M., Lund, Asger Bach, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetes. 70, 4, p. 1347-1356

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes

    Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats

    Baidassano, S., Gasbjerg, Lærke Smidt, Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Holst, Jens Juul & Hartmann, Bolette, 2019, In: Frontiers in Endocrinology. 10, 11 p., 492.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hartmann, Bolette, Christensen, M., Vilsbøll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: European Journal of Endocrinology. 170, 4, p. 529-538 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Pedersen, Jens, Christensen, M., Vilsboll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Journal of Endocrinology and Diabetes. 1, 1, p. 1-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing

    Bakhøj, S., Flint, A., Holst, Jens Juul & Tetens, Inge , 2003, In: European Journal of Clinical Nutrition. 57, 10, p. 1254-1261 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.

    Balas, B., Baig, M. R., Watson, C., Dunning, B. E., Ligueros-Saylan, M., Wang, Y., He, Y., Darland, C., Holst, Jens Juul, Deacon, Carolyn F., Cusi, K., Mari, A., Foley, J. E. & DeFronzo, R. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1249-55 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Glucagon-Like Peptide 1 and Atrial Natriuretic Peptide in a Female Mouse Model of Obstructive Pulmonary Disease

    Balk-Møller, E., Windeløv, Johanne Agerlin, Svendsen, B., Dal, Jenna Elizabeth Hunt, Ghiasi, S. M., Sorensen, Charlotte Mehlin, Holst, Jens Juul & Kissow, Hannelouise, 2020, In: Endocrine Research. 4, 1, 19 p., bvz034.

    Research output: Contribution to journal › Journal article › Research › peer-review

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