What is the impact of acute inflammation on muscle performance in geriatric patients?

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What is the impact of acute inflammation on muscle performance in geriatric patients? / Karlsen, Anders; Mackey, Abigail L.; Suetta, Charlotte; Kjaer, Michael.

I: Experimental Gerontology, Bind 138, 111008, 01.06.2020.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Karlsen, A, Mackey, AL, Suetta, C & Kjaer, M 2020, 'What is the impact of acute inflammation on muscle performance in geriatric patients?', Experimental Gerontology, bind 138, 111008. https://doi.org/10.1016/j.exger.2020.111008

APA

Karlsen, A., Mackey, A. L., Suetta, C., & Kjaer, M. (2020). What is the impact of acute inflammation on muscle performance in geriatric patients? Experimental Gerontology, 138, [111008]. https://doi.org/10.1016/j.exger.2020.111008

Vancouver

Karlsen A, Mackey AL, Suetta C, Kjaer M. What is the impact of acute inflammation on muscle performance in geriatric patients? Experimental Gerontology. 2020 jun. 1;138. 111008. https://doi.org/10.1016/j.exger.2020.111008

Author

Karlsen, Anders ; Mackey, Abigail L. ; Suetta, Charlotte ; Kjaer, Michael. / What is the impact of acute inflammation on muscle performance in geriatric patients?. I: Experimental Gerontology. 2020 ; Bind 138.

Bibtex

@article{3be04b939fdd4b93822b0df5233580a8,
title = "What is the impact of acute inflammation on muscle performance in geriatric patients?",
abstract = "There is growing evidence for a link between loss of skeletal muscle, impaired muscle performance, and systemic markers of acute inflammation in hospitalized geriatric patients. The present literature suggests a negative effect of acute inflammation at the time of hospital admission upon muscle performance and the change of this during the hospital stay, particularly in patients with persistent rather than resolved inflammation. Further, a few studies have reported a positive effect of anti-inflammatory medication upon recovery of muscle function in geriatric patients, but how this is mediated (e.g. inhibition of inflammatory cytokines) is not clear. In conclusion, a negative association between the presence of acute and persistent systemic markers of inflammation and various aspects of muscle function and its recovery after bedrest is observed in geriatric patients.",
author = "Anders Karlsen and Mackey, {Abigail L.} and Charlotte Suetta and Michael Kjaer",
year = "2020",
month = jun,
day = "1",
doi = "10.1016/j.exger.2020.111008",
language = "English",
volume = "138",
journal = "Experimental Gerontology",
issn = "0531-5565",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - What is the impact of acute inflammation on muscle performance in geriatric patients?

AU - Karlsen, Anders

AU - Mackey, Abigail L.

AU - Suetta, Charlotte

AU - Kjaer, Michael

PY - 2020/6/1

Y1 - 2020/6/1

N2 - There is growing evidence for a link between loss of skeletal muscle, impaired muscle performance, and systemic markers of acute inflammation in hospitalized geriatric patients. The present literature suggests a negative effect of acute inflammation at the time of hospital admission upon muscle performance and the change of this during the hospital stay, particularly in patients with persistent rather than resolved inflammation. Further, a few studies have reported a positive effect of anti-inflammatory medication upon recovery of muscle function in geriatric patients, but how this is mediated (e.g. inhibition of inflammatory cytokines) is not clear. In conclusion, a negative association between the presence of acute and persistent systemic markers of inflammation and various aspects of muscle function and its recovery after bedrest is observed in geriatric patients.

AB - There is growing evidence for a link between loss of skeletal muscle, impaired muscle performance, and systemic markers of acute inflammation in hospitalized geriatric patients. The present literature suggests a negative effect of acute inflammation at the time of hospital admission upon muscle performance and the change of this during the hospital stay, particularly in patients with persistent rather than resolved inflammation. Further, a few studies have reported a positive effect of anti-inflammatory medication upon recovery of muscle function in geriatric patients, but how this is mediated (e.g. inhibition of inflammatory cytokines) is not clear. In conclusion, a negative association between the presence of acute and persistent systemic markers of inflammation and various aspects of muscle function and its recovery after bedrest is observed in geriatric patients.

U2 - 10.1016/j.exger.2020.111008

DO - 10.1016/j.exger.2020.111008

M3 - Journal article

C2 - 32592832

VL - 138

JO - Experimental Gerontology

JF - Experimental Gerontology

SN - 0531-5565

M1 - 111008

ER -

ID: 243465241