The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging

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The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging. / Frandsen, Jacob; Beck, Thomas; Langkilde, Caecilie Haugaard; Larsen, Steen; Dela, Flemming; Helge, Jorn W.

I: European Journal of Sport Science, Bind 21, Nr. 1, 2021, s. 69-76.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Frandsen, J, Beck, T, Langkilde, CH, Larsen, S, Dela, F & Helge, JW 2021, 'The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging', European Journal of Sport Science, bind 21, nr. 1, s. 69-76. https://doi.org/10.1080/17461391.2020.1721563

APA

Frandsen, J., Beck, T., Langkilde, C. H., Larsen, S., Dela, F., & Helge, J. W. (2021). The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging. European Journal of Sport Science, 21(1), 69-76. https://doi.org/10.1080/17461391.2020.1721563

Vancouver

Frandsen J, Beck T, Langkilde CH, Larsen S, Dela F, Helge JW. The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging. European Journal of Sport Science. 2021;21(1):69-76. https://doi.org/10.1080/17461391.2020.1721563

Author

Frandsen, Jacob ; Beck, Thomas ; Langkilde, Caecilie Haugaard ; Larsen, Steen ; Dela, Flemming ; Helge, Jorn W. / The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging. I: European Journal of Sport Science. 2021 ; Bind 21, Nr. 1. s. 69-76.

Bibtex

@article{f10bed0af88349e1aa105ee98eb6da41,
title = "The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging",
abstract = "An attenuated ability to appropriately oxidize fat (metabolic inflexibility) has been associated with the development of obesity and type 2 diabetes. Previous studies have found that regular exercise training increases the body's ability to oxidize fat during exercise, but also shown that fat oxidation at the same relative and absolute exercise intensity is lower in old compared with young adults. Based on these studies we investigated the effect of training status on the whole-body peak fat oxidation rate (PFO) during exercise in young and middle-aged trained and untrained men. We hypothesized that aging was associated with decreased PFO, but regular exercise training could counteract this decline. 36 healthy non-overweight young and middle-aged men were recruited into a four groups: young (27 [24-30] yrs, (Mean [95% CI])) untrained (O(2)peak: 47 [44-49] ml/min/kg), young (28 [26-30] yrs) trained (O(2)peak: 64 [62-67] ml/min/kg), middle-aged (55 [53-57] yrs) untrained (O(2)peak: 37 [32-42] ml/min/kg) and middle-aged (54 [51-57] yrs) trained (O(2)peak: 55 [51-58] ml/min/kg). PFO was measured by indirect calorimetry while subjects performed a validated incremental exercise protocol on a cycle ergometer. Whole-body peak fat oxidation rate was higher in the young trained compared to young untrained subjects (0.70 [0.65-0.75] vs.0.45 [0.36-0.54] g/min, post-hoc: p < 0.001); however, this training effect was attenuated in middle-aged trained and untrained subjects (0.44 [0.38-0.50] vs. 0.41 [0.35-0.47] g/min, post-hoc: p = 0.83, respectively). In summary, these findings suggest that the training induced effects on whole-body fat oxidation found in young men may be attenuated in middle-aged men.",
keywords = "Fat oxidation rate, FATmax, training status, age, aging",
author = "Jacob Frandsen and Thomas Beck and Langkilde, {Caecilie Haugaard} and Steen Larsen and Flemming Dela and Helge, {Jorn W.}",
year = "2021",
doi = "10.1080/17461391.2020.1721563",
language = "English",
volume = "21",
pages = "69--76",
journal = "European Journal of Sport Science",
issn = "1746-1391",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging

AU - Frandsen, Jacob

AU - Beck, Thomas

AU - Langkilde, Caecilie Haugaard

AU - Larsen, Steen

AU - Dela, Flemming

AU - Helge, Jorn W.

PY - 2021

Y1 - 2021

N2 - An attenuated ability to appropriately oxidize fat (metabolic inflexibility) has been associated with the development of obesity and type 2 diabetes. Previous studies have found that regular exercise training increases the body's ability to oxidize fat during exercise, but also shown that fat oxidation at the same relative and absolute exercise intensity is lower in old compared with young adults. Based on these studies we investigated the effect of training status on the whole-body peak fat oxidation rate (PFO) during exercise in young and middle-aged trained and untrained men. We hypothesized that aging was associated with decreased PFO, but regular exercise training could counteract this decline. 36 healthy non-overweight young and middle-aged men were recruited into a four groups: young (27 [24-30] yrs, (Mean [95% CI])) untrained (O(2)peak: 47 [44-49] ml/min/kg), young (28 [26-30] yrs) trained (O(2)peak: 64 [62-67] ml/min/kg), middle-aged (55 [53-57] yrs) untrained (O(2)peak: 37 [32-42] ml/min/kg) and middle-aged (54 [51-57] yrs) trained (O(2)peak: 55 [51-58] ml/min/kg). PFO was measured by indirect calorimetry while subjects performed a validated incremental exercise protocol on a cycle ergometer. Whole-body peak fat oxidation rate was higher in the young trained compared to young untrained subjects (0.70 [0.65-0.75] vs.0.45 [0.36-0.54] g/min, post-hoc: p < 0.001); however, this training effect was attenuated in middle-aged trained and untrained subjects (0.44 [0.38-0.50] vs. 0.41 [0.35-0.47] g/min, post-hoc: p = 0.83, respectively). In summary, these findings suggest that the training induced effects on whole-body fat oxidation found in young men may be attenuated in middle-aged men.

AB - An attenuated ability to appropriately oxidize fat (metabolic inflexibility) has been associated with the development of obesity and type 2 diabetes. Previous studies have found that regular exercise training increases the body's ability to oxidize fat during exercise, but also shown that fat oxidation at the same relative and absolute exercise intensity is lower in old compared with young adults. Based on these studies we investigated the effect of training status on the whole-body peak fat oxidation rate (PFO) during exercise in young and middle-aged trained and untrained men. We hypothesized that aging was associated with decreased PFO, but regular exercise training could counteract this decline. 36 healthy non-overweight young and middle-aged men were recruited into a four groups: young (27 [24-30] yrs, (Mean [95% CI])) untrained (O(2)peak: 47 [44-49] ml/min/kg), young (28 [26-30] yrs) trained (O(2)peak: 64 [62-67] ml/min/kg), middle-aged (55 [53-57] yrs) untrained (O(2)peak: 37 [32-42] ml/min/kg) and middle-aged (54 [51-57] yrs) trained (O(2)peak: 55 [51-58] ml/min/kg). PFO was measured by indirect calorimetry while subjects performed a validated incremental exercise protocol on a cycle ergometer. Whole-body peak fat oxidation rate was higher in the young trained compared to young untrained subjects (0.70 [0.65-0.75] vs.0.45 [0.36-0.54] g/min, post-hoc: p < 0.001); however, this training effect was attenuated in middle-aged trained and untrained subjects (0.44 [0.38-0.50] vs. 0.41 [0.35-0.47] g/min, post-hoc: p = 0.83, respectively). In summary, these findings suggest that the training induced effects on whole-body fat oxidation found in young men may be attenuated in middle-aged men.

KW - Fat oxidation rate

KW - FATmax

KW - training status

KW - age

KW - aging

U2 - 10.1080/17461391.2020.1721563

DO - 10.1080/17461391.2020.1721563

M3 - Journal article

C2 - 31973646

VL - 21

SP - 69

EP - 76

JO - European Journal of Sport Science

JF - European Journal of Sport Science

SN - 1746-1391

IS - 1

ER -

ID: 236987303