Terapi med stamceller til akut iskaemisk hjertesygdom, myokardial regeneration?
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Terapi med stamceller til akut iskaemisk hjertesygdom, myokardial regeneration? / Ripa, Rasmus Sejersten; Wang, Yongzhong; Jørgensen, Erik; Kastrup, Jens.
I: Ugeskrift for Laeger, Bind 169, Nr. 2, 08.01.2007, s. 119-22.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Terapi med stamceller til akut iskaemisk hjertesygdom, myokardial regeneration?
AU - Ripa, Rasmus Sejersten
AU - Wang, Yongzhong
AU - Jørgensen, Erik
AU - Kastrup, Jens
PY - 2007/1/8
Y1 - 2007/1/8
N2 - Treatment of ischemic heart disease with injections of bone-marrow-derived stem cells is a promising new modality. However, recent medium-sized placebo controlled trials in patients with acute myocardial infarction have not been conclusive regarding the treatment effect. This short review aims to elucidate some of the unresolved issues raised by the first clinical trials. These include long-term safety, tissue-distribution of infused cells, selecting the optimal cell type and number, timing of the treatment, and the mechanism of a potential treatment effect.
AB - Treatment of ischemic heart disease with injections of bone-marrow-derived stem cells is a promising new modality. However, recent medium-sized placebo controlled trials in patients with acute myocardial infarction have not been conclusive regarding the treatment effect. This short review aims to elucidate some of the unresolved issues raised by the first clinical trials. These include long-term safety, tissue-distribution of infused cells, selecting the optimal cell type and number, timing of the treatment, and the mechanism of a potential treatment effect.
KW - Clinical Trials as Topic
KW - Heart
KW - Hematopoietic Stem Cell Transplantation
KW - Humans
KW - Myocardial Ischemia
KW - Regeneration
KW - Treatment Outcome
M3 - Tidsskriftartikel
C2 - 17227657
VL - 169
SP - 119
EP - 122
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 2
ER -
ID: 47744169