Systemic treatment with epidermal growth factor in pigs induces ductal proliferations in the pancreas
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Epidermal growth factor (EGF), transforming growth factor alpha (TGF-alpha), and the EGF receptor are often overexpressed in chronic pancreatitis and in malignant pancreatic growth. Transgenic mice overexpressing TGF-alpha develop tissue changes in the pancrease resembling changes found in chronic pancreatitis. The effects of systemic treatment with EGF on the porcine pancrease were investigated in this study.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Gastroenterology |
Vol/bind | 113 |
Udgave nummer | 4 |
Sider (fra-til) | 1367-1374 |
Antal sider | 8 |
ISSN | 0016-5085 |
Status | Udgivet - okt. 1997 |
ID: 226386