Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice

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Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice. / Barfod, Kenneth K; Poulsen, Steen Seier; Hammer, Maria; Larsen, Søren T.

I: B M C Microbiology, Bind 10, 03.09.2010, s. 233.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Barfod, KK, Poulsen, SS, Hammer, M & Larsen, ST 2010, 'Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice', B M C Microbiology, bind 10, s. 233. https://doi.org/10.1186/1471-2180-10-233

APA

Barfod, K. K., Poulsen, S. S., Hammer, M., & Larsen, S. T. (2010). Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice. B M C Microbiology, 10, 233. https://doi.org/10.1186/1471-2180-10-233

Vancouver

Barfod KK, Poulsen SS, Hammer M, Larsen ST. Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice. B M C Microbiology. 2010 sep. 3;10:233. https://doi.org/10.1186/1471-2180-10-233

Author

Barfod, Kenneth K ; Poulsen, Steen Seier ; Hammer, Maria ; Larsen, Søren T. / Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice. I: B M C Microbiology. 2010 ; Bind 10. s. 233.

Bibtex

@article{db598d3341ab47aca96bb3e740bfc052,
title = "Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice",
abstract = "The aim of the present study was to assess possible health effects of airway exposures to Bacillus thuringiensis (Bt) based biopesticides in mice. Endpoints were lung inflammation evaluated by presence of inflammatory cells in bronchoalveolar lavage fluid (BALF), clearance of bacteria from the lung lumen and histological alterations of the lungs. Hazard identifications of the biopesticides were carried out using intratracheal (i.t.) instillation, followed by an inhalation study. The two commercial biopesticides used were based on the Bt. subspecies kurstaki and israelensis, respectively. Groups of BALB/c mice were i.t instilled with one bolus (3.5 × 105 or 3.4 × 106 colony forming units (CFU) per mouse) of either biopesticide. Control mice were instilled with sterile water. BALFs were collected and the inflammatory cells were counted and differentiated. The BALFs were also subjected to CFU counts.",
keywords = "Animals, Bacillus thuringiensis, Bronchoalveolar Lavage Fluid, Female, Humans, Inhalation Exposure, Lung, Mice, Mice, Inbred BALB C, Models, Animal, Pest Control, Biological, Pesticides, Respiratory System",
author = "Barfod, {Kenneth K} and Poulsen, {Steen Seier} and Maria Hammer and Larsen, {S{\o}ren T.}",
year = "2010",
month = sep,
day = "3",
doi = "10.1186/1471-2180-10-233",
language = "English",
volume = "10",
pages = "233",
journal = "BMC Microbiology",
issn = "1471-2180",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Sub-chronic lung inflammation after airway exposures to Bacillus thuringiensis biopesticides in mice

AU - Barfod, Kenneth K

AU - Poulsen, Steen Seier

AU - Hammer, Maria

AU - Larsen, Søren T.

PY - 2010/9/3

Y1 - 2010/9/3

N2 - The aim of the present study was to assess possible health effects of airway exposures to Bacillus thuringiensis (Bt) based biopesticides in mice. Endpoints were lung inflammation evaluated by presence of inflammatory cells in bronchoalveolar lavage fluid (BALF), clearance of bacteria from the lung lumen and histological alterations of the lungs. Hazard identifications of the biopesticides were carried out using intratracheal (i.t.) instillation, followed by an inhalation study. The two commercial biopesticides used were based on the Bt. subspecies kurstaki and israelensis, respectively. Groups of BALB/c mice were i.t instilled with one bolus (3.5 × 105 or 3.4 × 106 colony forming units (CFU) per mouse) of either biopesticide. Control mice were instilled with sterile water. BALFs were collected and the inflammatory cells were counted and differentiated. The BALFs were also subjected to CFU counts.

AB - The aim of the present study was to assess possible health effects of airway exposures to Bacillus thuringiensis (Bt) based biopesticides in mice. Endpoints were lung inflammation evaluated by presence of inflammatory cells in bronchoalveolar lavage fluid (BALF), clearance of bacteria from the lung lumen and histological alterations of the lungs. Hazard identifications of the biopesticides were carried out using intratracheal (i.t.) instillation, followed by an inhalation study. The two commercial biopesticides used were based on the Bt. subspecies kurstaki and israelensis, respectively. Groups of BALB/c mice were i.t instilled with one bolus (3.5 × 105 or 3.4 × 106 colony forming units (CFU) per mouse) of either biopesticide. Control mice were instilled with sterile water. BALFs were collected and the inflammatory cells were counted and differentiated. The BALFs were also subjected to CFU counts.

KW - Animals

KW - Bacillus thuringiensis

KW - Bronchoalveolar Lavage Fluid

KW - Female

KW - Humans

KW - Inhalation Exposure

KW - Lung

KW - Mice

KW - Mice, Inbred BALB C

KW - Models, Animal

KW - Pest Control, Biological

KW - Pesticides

KW - Respiratory System

U2 - 10.1186/1471-2180-10-233

DO - 10.1186/1471-2180-10-233

M3 - Journal article

C2 - 20815884

VL - 10

SP - 233

JO - BMC Microbiology

JF - BMC Microbiology

SN - 1471-2180

ER -

ID: 33792411