Stereomicroscopic examination of stained rectal biopsies in ulcerative colitis and Crohn's disease
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Stereomicroscopic examination of stained rectal biopsies in ulcerative colitis and Crohn's disease. / Poulsen, Steen Seier.
I: Scandinavian Journal of Gastroenterology, Bind 15, Nr. 5, 1980, s. 535-44.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Stereomicroscopic examination of stained rectal biopsies in ulcerative colitis and Crohn's disease
AU - Poulsen, Steen Seier
PY - 1980
Y1 - 1980
N2 - Rectal biopsy samples from 22 healthy control subjects, 54 patients with ulcerative colitis, and 34 with Crohn's disease with involvement of the colon or rectum were investigated in a stereomicroscopic study. Samples were stained as whole mounts with Alcian Green before the stereomicroscopic examination. In ulcerative colitis, biopsies almost constantly showed changes in the mucosal surface pattern, including irregular, enlarged crypt openings filled with exudate, granulated and bulging surface, and patchy localization of the goblet cells. There was a close correlation between the stereomicroscopic findings and the clinical disease activity, the sigmoidoscopic findings, and the histologic activity. Apart from the stereomicroscopic observation of small superficial erosions in one fourth of the biopsies, no changes of diagnostic value were observed in Crohn's disease.
AB - Rectal biopsy samples from 22 healthy control subjects, 54 patients with ulcerative colitis, and 34 with Crohn's disease with involvement of the colon or rectum were investigated in a stereomicroscopic study. Samples were stained as whole mounts with Alcian Green before the stereomicroscopic examination. In ulcerative colitis, biopsies almost constantly showed changes in the mucosal surface pattern, including irregular, enlarged crypt openings filled with exudate, granulated and bulging surface, and patchy localization of the goblet cells. There was a close correlation between the stereomicroscopic findings and the clinical disease activity, the sigmoidoscopic findings, and the histologic activity. Apart from the stereomicroscopic observation of small superficial erosions in one fourth of the biopsies, no changes of diagnostic value were observed in Crohn's disease.
KW - Adolescent
KW - Adult
KW - Aged
KW - Biopsy
KW - Colitis, Ulcerative
KW - Colon
KW - Crohn Disease
KW - Humans
KW - Intestinal Mucosa
KW - Microscopy
KW - Middle Aged
KW - Rectum
KW - Sigmoidoscopy
KW - Staining and Labeling
M3 - Journal article
C2 - 6160609
VL - 15
SP - 535
EP - 544
JO - Scandinavian Journal of Gastroenterology
JF - Scandinavian Journal of Gastroenterology
SN - 0036-5521
IS - 5
ER -
ID: 47490159