Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

K V Haderslev, P B Jeppesen, B Hartmann, J Thulesen, H A Sorensen, J Graff, F Tofteng, S S Poulsen, J L Madsen, J J Holst, M Staun, P B Mortensen, Steen Seier Poulsen

Glucagon-like peptide 2 (GLP-2) is a newly discovered intestinotrophic hormone. We have recently reported that a 5-week GLP-2 treatment improved the intestinal absorptive capacity of short-bowel patients with no colon. Additionally, GLP-2 treatment was associated with changes in body composition that included a significant increase in total body bone mass. This article describes the effect of GLP-2 on spinal and hip bone mineral density (BMD) and biochemical markers of bone turnover in these patients.
OriginalsprogEngelsk
TidsskriftScandinavian Journal of Gastroenterology
Vol/bind37
Udgave nummer4
Sider (fra-til)392-8
Antal sider7
ISSN0036-5521
StatusUdgivet - 1 apr. 2002

ID: 33793088