Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma

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Standard

Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma. / Lawaetz, Mads; Homøe, Preben.

I: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Bind 118, Nr. 6, 12.2014, s. 642-646.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lawaetz, M & Homøe, P 2014, 'Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma', Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, bind 118, nr. 6, s. 642-646. https://doi.org/10.1016/j.oooo.2014.08.001

APA

Lawaetz, M., & Homøe, P. (2014). Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 118(6), 642-646. https://doi.org/10.1016/j.oooo.2014.08.001

Vancouver

Lawaetz M, Homøe P. Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2014 dec.;118(6):642-646. https://doi.org/10.1016/j.oooo.2014.08.001

Author

Lawaetz, Mads ; Homøe, Preben. / Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma. I: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2014 ; Bind 118, Nr. 6. s. 642-646.

Bibtex

@article{5242ac6cf8ac41c7980aec7f6c570905,

title = "Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma",

abstract = "OBJECTIVE: The purpose of this study was to examine which factors are associated with inadequate surgical margins and to assess the postoperative consequences.STUDY DESIGN: A retrospective cohort of 110 patients with oral squamous cell carcinoma treated with surgery during a 2-year period was examined. Clinical, histopathologic, and operative variables were related to the surgical margin status. Furthermore postoperative treatment data were compared with margin status.RESULTS: Univariate statistically significant associations were found between the tumor site in the floor of mouth, more advanced T-stage, increasing tumor thickness, and inadequate margins. Of the patients with involved margins, 87% were treated with postoperative radiotherapy or re-resection, but among patients with close margins, only 35% received either radiotherapy or re-resection.CONCLUSIONS: Clinical and histopathologic factors were associated with the inadequate margin. Postoperative treatment for patients with close margins is controversial, and more studies are needed to define clear guidelines.",

author = "Mads Lawaetz and Preben Hom{\o}e",

year = "2014",

month = dec,

doi = "10.1016/j.oooo.2014.08.001",

language = "English",

volume = "118",

pages = "642--646",

journal = "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology",

issn = "2212-4403",

publisher = "Elsevier",

number = "6",

}

RIS

TY - JOUR

T1 - Risk factors for and consequences of inadequate surgical margins in oral squamous cell carcinoma

AU - Lawaetz, Mads

AU - Homøe, Preben

PY - 2014/12

Y1 - 2014/12

N2 - OBJECTIVE: The purpose of this study was to examine which factors are associated with inadequate surgical margins and to assess the postoperative consequences.STUDY DESIGN: A retrospective cohort of 110 patients with oral squamous cell carcinoma treated with surgery during a 2-year period was examined. Clinical, histopathologic, and operative variables were related to the surgical margin status. Furthermore postoperative treatment data were compared with margin status.RESULTS: Univariate statistically significant associations were found between the tumor site in the floor of mouth, more advanced T-stage, increasing tumor thickness, and inadequate margins. Of the patients with involved margins, 87% were treated with postoperative radiotherapy or re-resection, but among patients with close margins, only 35% received either radiotherapy or re-resection.CONCLUSIONS: Clinical and histopathologic factors were associated with the inadequate margin. Postoperative treatment for patients with close margins is controversial, and more studies are needed to define clear guidelines.

AB - OBJECTIVE: The purpose of this study was to examine which factors are associated with inadequate surgical margins and to assess the postoperative consequences.STUDY DESIGN: A retrospective cohort of 110 patients with oral squamous cell carcinoma treated with surgery during a 2-year period was examined. Clinical, histopathologic, and operative variables were related to the surgical margin status. Furthermore postoperative treatment data were compared with margin status.RESULTS: Univariate statistically significant associations were found between the tumor site in the floor of mouth, more advanced T-stage, increasing tumor thickness, and inadequate margins. Of the patients with involved margins, 87% were treated with postoperative radiotherapy or re-resection, but among patients with close margins, only 35% received either radiotherapy or re-resection.CONCLUSIONS: Clinical and histopathologic factors were associated with the inadequate margin. Postoperative treatment for patients with close margins is controversial, and more studies are needed to define clear guidelines.

U2 - 10.1016/j.oooo.2014.08.001

DO - 10.1016/j.oooo.2014.08.001

M3 - Journal article

C2 - 25457884

VL - 118

SP - 642

EP - 646

JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

SN - 2212-4403

IS - 6

ER -

ID: 135490036

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