Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

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Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules. / Anghinoni, João M.; Birmann, Paloma T.; da Rocha, Marcia J.; Gomes, Caroline S.; Davies, Michael J.; Brüning, César A.; Savegnago, Lucielli; Lenardão, Eder J.

I: Molecules, Bind 28, Nr. 21, 7349, 2023, s. 1-45.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Anghinoni, JM, Birmann, PT, da Rocha, MJ, Gomes, CS, Davies, MJ, Brüning, CA, Savegnago, L & Lenardão, EJ 2023, 'Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules', Molecules, bind 28, nr. 21, 7349, s. 1-45. https://doi.org/10.3390/molecules28217349

APA

Anghinoni, J. M., Birmann, P. T., da Rocha, M. J., Gomes, C. S., Davies, M. J., Brüning, C. A., Savegnago, L., & Lenardão, E. J. (2023). Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules. Molecules, 28(21), 1-45. [7349]. https://doi.org/10.3390/molecules28217349

Vancouver

Anghinoni JM, Birmann PT, da Rocha MJ, Gomes CS, Davies MJ, Brüning CA o.a. Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules. Molecules. 2023;28(21):1-45. 7349. https://doi.org/10.3390/molecules28217349

Author

Anghinoni, João M. ; Birmann, Paloma T. ; da Rocha, Marcia J. ; Gomes, Caroline S. ; Davies, Michael J. ; Brüning, César A. ; Savegnago, Lucielli ; Lenardão, Eder J. / Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules. I: Molecules. 2023 ; Bind 28, Nr. 21. s. 1-45.

Bibtex

@article{bcebd25d944943dc82d8dabb11b7a077,
title = "Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules",
abstract = "Selenium is an essential trace element in living organisms, and is present in selenoenzymes with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR). The search for small selenium-containing molecules that mimic selenoenzymes is a strong field of research in organic and medicinal chemistry. In this review, we review the synthesis and bioassays of new and known organoselenium compounds with antioxidant activity, covering the last five years. A detailed description of the synthetic procedures and the performed in vitro and in vivo bioassays is presented, highlighting the most active compounds in each series.",
keywords = "ABTS, antioxidant, catalase, DPPH, FRAP, GPx-like, lipid peroxidation, organoselenium, SOD",
author = "Anghinoni, {Jo{\~a}o M.} and Birmann, {Paloma T.} and {da Rocha}, {Marcia J.} and Gomes, {Caroline S.} and Davies, {Michael J.} and Br{\"u}ning, {C{\'e}sar A.} and Lucielli Savegnago and Lenard{\~a}o, {Eder J.}",
note = "Publisher Copyright: {\textcopyright} 2023 by the authors.",
year = "2023",
doi = "10.3390/molecules28217349",
language = "English",
volume = "28",
pages = "1--45",
journal = "Molecules",
issn = "1420-3049",
publisher = "M D P I AG",
number = "21",

}

RIS

TY - JOUR

T1 - Recent Advances in the Synthesis and Antioxidant Activity of Low Molecular Mass Organoselenium Molecules

AU - Anghinoni, João M.

AU - Birmann, Paloma T.

AU - da Rocha, Marcia J.

AU - Gomes, Caroline S.

AU - Davies, Michael J.

AU - Brüning, César A.

AU - Savegnago, Lucielli

AU - Lenardão, Eder J.

N1 - Publisher Copyright: © 2023 by the authors.

PY - 2023

Y1 - 2023

N2 - Selenium is an essential trace element in living organisms, and is present in selenoenzymes with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR). The search for small selenium-containing molecules that mimic selenoenzymes is a strong field of research in organic and medicinal chemistry. In this review, we review the synthesis and bioassays of new and known organoselenium compounds with antioxidant activity, covering the last five years. A detailed description of the synthetic procedures and the performed in vitro and in vivo bioassays is presented, highlighting the most active compounds in each series.

AB - Selenium is an essential trace element in living organisms, and is present in selenoenzymes with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR). The search for small selenium-containing molecules that mimic selenoenzymes is a strong field of research in organic and medicinal chemistry. In this review, we review the synthesis and bioassays of new and known organoselenium compounds with antioxidant activity, covering the last five years. A detailed description of the synthetic procedures and the performed in vitro and in vivo bioassays is presented, highlighting the most active compounds in each series.

KW - ABTS

KW - antioxidant

KW - catalase

KW - DPPH

KW - FRAP

KW - GPx-like

KW - lipid peroxidation

KW - organoselenium

KW - SOD

UR - http://www.scopus.com/inward/record.url?scp=85176325364&partnerID=8YFLogxK

U2 - 10.3390/molecules28217349

DO - 10.3390/molecules28217349

M3 - Review

C2 - 37959771

AN - SCOPUS:85176325364

VL - 28

SP - 1

EP - 45

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 21

M1 - 7349

ER -

ID: 374307933