Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake
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Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake. / Hagemann, Christoffer A.; Gasbjerg, Lærke S.; Christensen, Mikkel B.; Knop, Filip K.
I: STAR Protocols, Bind 4, Nr. 1, 102070, 2023.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake
AU - Hagemann, Christoffer A.
AU - Gasbjerg, Lærke S.
AU - Christensen, Mikkel B.
AU - Knop, Filip K.
N1 - Publisher Copyright: © 2023 The Author(s)
PY - 2023
Y1 - 2023
N2 - Here, we present a protocol for a randomized, double-blind, placebo-controlled, crossover trial to evaluate the effects of a continuous intravenous infusion of a native liver-derived hormone, liver-expressed antimicrobial peptide 2 (LEAP2), on postprandial glucose metabolism, appetite and satiety sensations, and ad libitum food intake in humans. We describe the preparation of the exogenous hormone administration and participants. We then detail the liquid mixed meal, ad libitum meal test, and blood sampling procedures for assessing postprandial glucose metabolism and food intake. For complete details on the use and execution of this protocol, please refer to Hagemann et al. (2022).1
AB - Here, we present a protocol for a randomized, double-blind, placebo-controlled, crossover trial to evaluate the effects of a continuous intravenous infusion of a native liver-derived hormone, liver-expressed antimicrobial peptide 2 (LEAP2), on postprandial glucose metabolism, appetite and satiety sensations, and ad libitum food intake in humans. We describe the preparation of the exogenous hormone administration and participants. We then detail the liquid mixed meal, ad libitum meal test, and blood sampling procedures for assessing postprandial glucose metabolism and food intake. For complete details on the use and execution of this protocol, please refer to Hagemann et al. (2022).1
KW - Behavior
KW - Clinical Protocol
KW - Metabolism
UR - http://www.scopus.com/inward/record.url?scp=85147261915&partnerID=8YFLogxK
U2 - 10.1016/j.xpro.2023.102070
DO - 10.1016/j.xpro.2023.102070
M3 - Journal article
C2 - 36853704
AN - SCOPUS:85147261915
VL - 4
JO - STAR Protocols
JF - STAR Protocols
SN - 2666-1667
IS - 1
M1 - 102070
ER -
ID: 335676267