Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside

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Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside. / Midtkandal, Rebecca R.; Redpath, Philip; Trammell, Samuel A J; MacDonald, Simon J F; Brenner, Charles; Migaud, Marie E.

I: Bioorganic and Medicinal Chemistry Letters, Bind 22, Nr. 16, 15.08.2012, s. 5204-5207.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Midtkandal, RR, Redpath, P, Trammell, SAJ, MacDonald, SJF, Brenner, C & Migaud, ME 2012, 'Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside', Bioorganic and Medicinal Chemistry Letters, bind 22, nr. 16, s. 5204-5207. https://doi.org/10.1016/j.bmcl.2012.06.069

APA

Midtkandal, R. R., Redpath, P., Trammell, S. A. J., MacDonald, S. J. F., Brenner, C., & Migaud, M. E. (2012). Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside. Bioorganic and Medicinal Chemistry Letters, 22(16), 5204-5207. https://doi.org/10.1016/j.bmcl.2012.06.069

Vancouver

Midtkandal RR, Redpath P, Trammell SAJ, MacDonald SJF, Brenner C, Migaud ME. Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside. Bioorganic and Medicinal Chemistry Letters. 2012 aug. 15;22(16):5204-5207. https://doi.org/10.1016/j.bmcl.2012.06.069

Author

Midtkandal, Rebecca R. ; Redpath, Philip ; Trammell, Samuel A J ; MacDonald, Simon J F ; Brenner, Charles ; Migaud, Marie E. / Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside. I: Bioorganic and Medicinal Chemistry Letters. 2012 ; Bind 22, Nr. 16. s. 5204-5207.

Bibtex

@article{92ba6717dae644399a3ff9456d9aca70,
title = "Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside",
abstract = "2-Deoxy-C-nucleosides are a subcategory of C-nucleosides that has not been explored extensively, largely because the synthesis is less facile. Flexible synthetic procedures giving access to 2-deoxy-C-nucleosides are therefore of interest. To exemplify the versatility and highlight the limitations of a synthetic route recently developed to that effect, the first synthesis of 2-deoxy benzamide riboside is reported. Biological properties of this novel C-nucleoside are also discussed.",
keywords = "Benzamide riboside, C-Nucleoside, Inosine monophosphate dehydrogenase, Intramolecular cyclisation, Nicotinamide adenine dinucleotide",
author = "Midtkandal, {Rebecca R.} and Philip Redpath and Trammell, {Samuel A J} and MacDonald, {Simon J F} and Charles Brenner and Migaud, {Marie E.}",
year = "2012",
month = aug,
day = "15",
doi = "10.1016/j.bmcl.2012.06.069",
language = "English",
volume = "22",
pages = "5204--5207",
journal = "Bioorganic & Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Pergamon Press",
number = "16",

}

RIS

TY - JOUR

T1 - Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside

AU - Midtkandal, Rebecca R.

AU - Redpath, Philip

AU - Trammell, Samuel A J

AU - MacDonald, Simon J F

AU - Brenner, Charles

AU - Migaud, Marie E.

PY - 2012/8/15

Y1 - 2012/8/15

N2 - 2-Deoxy-C-nucleosides are a subcategory of C-nucleosides that has not been explored extensively, largely because the synthesis is less facile. Flexible synthetic procedures giving access to 2-deoxy-C-nucleosides are therefore of interest. To exemplify the versatility and highlight the limitations of a synthetic route recently developed to that effect, the first synthesis of 2-deoxy benzamide riboside is reported. Biological properties of this novel C-nucleoside are also discussed.

AB - 2-Deoxy-C-nucleosides are a subcategory of C-nucleosides that has not been explored extensively, largely because the synthesis is less facile. Flexible synthetic procedures giving access to 2-deoxy-C-nucleosides are therefore of interest. To exemplify the versatility and highlight the limitations of a synthetic route recently developed to that effect, the first synthesis of 2-deoxy benzamide riboside is reported. Biological properties of this novel C-nucleoside are also discussed.

KW - Benzamide riboside

KW - C-Nucleoside

KW - Inosine monophosphate dehydrogenase

KW - Intramolecular cyclisation

KW - Nicotinamide adenine dinucleotide

UR - http://www.scopus.com/inward/record.url?scp=84864411406&partnerID=8YFLogxK

U2 - 10.1016/j.bmcl.2012.06.069

DO - 10.1016/j.bmcl.2012.06.069

M3 - Journal article

C2 - 22795628

AN - SCOPUS:84864411406

VL - 22

SP - 5204

EP - 5207

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

SN - 0960-894X

IS - 16

ER -

ID: 220855816