Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients

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Standard

Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients. / Karlsen, Anders; Cullum, Christopher Kjaer; Norheim, Kristoffer Larsen; Scheel, Frederik Ulrik; Zinglersen, Amanda Hempel; Vahlgren, Julie; Schjerling, Peter; Kjaer, Michael; Mackey, Abigail L.

I: Medicine and Science in Sports and Exercise, Bind 52, Nr. 4, 2020, s. 773-784.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Karlsen, A, Cullum, CK, Norheim, KL, Scheel, FU, Zinglersen, AH, Vahlgren, J, Schjerling, P, Kjaer, M & Mackey, AL 2020, 'Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients', Medicine and Science in Sports and Exercise, bind 52, nr. 4, s. 773-784. https://doi.org/10.1249/MSS.0000000000002191

APA

Karlsen, A., Cullum, C. K., Norheim, K. L., Scheel, F. U., Zinglersen, A. H., Vahlgren, J., Schjerling, P., Kjaer, M., & Mackey, A. L. (2020). Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients. Medicine and Science in Sports and Exercise, 52(4), 773-784. https://doi.org/10.1249/MSS.0000000000002191

Vancouver

Karlsen A, Cullum CK, Norheim KL, Scheel FU, Zinglersen AH, Vahlgren J o.a. Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients. Medicine and Science in Sports and Exercise. 2020;52(4):773-784. https://doi.org/10.1249/MSS.0000000000002191

Author

Karlsen, Anders ; Cullum, Christopher Kjaer ; Norheim, Kristoffer Larsen ; Scheel, Frederik Ulrik ; Zinglersen, Amanda Hempel ; Vahlgren, Julie ; Schjerling, Peter ; Kjaer, Michael ; Mackey, Abigail L. / Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients. I: Medicine and Science in Sports and Exercise. 2020 ; Bind 52, Nr. 4. s. 773-784.

Bibtex

@article{eb19ce08d6a142ecbb005c201335b558,
title = "Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients",
abstract = "Aim To examine changes in lean mass during hospitalization in geriatric patients and the effect of muscle activation by neuromuscular electrical stimulation. Methods Thirteen patients (69-94 years) at a geriatric ward completed tests at hospital admission (day 2-3) and discharge (day 8-10). One leg received daily stimulation of the knee extensors while the other leg served as a control leg. Lean mass was evaluated by DEXA scans and muscle thickness by ultrasound scans. Muscle biopsies were collected from both legs at admission and discharge in 9 patients and analyzed for fibre size, satellite cell number and activation and expression of genes associated with muscle protein synthesis and breakdown, connective tissue and cellular stress. Results The relative decline in leg lean mass and midthigh region lean mass was larger in the control (-2.8±1.5%) vs. the stimulated leg (-0.5±1.4%, p",
keywords = "Muscle Atrophy, Muscle Activation, Neuromuscular Electrical Stimulation, Satellite Cells, Gene Expression",
author = "Anders Karlsen and Cullum, {Christopher Kjaer} and Norheim, {Kristoffer Larsen} and Scheel, {Frederik Ulrik} and Zinglersen, {Amanda Hempel} and Julie Vahlgren and Peter Schjerling and Michael Kjaer and Mackey, {Abigail L.}",
year = "2020",
doi = "10.1249/MSS.0000000000002191",
language = "English",
volume = "52",
pages = "773--784",
journal = "Medicine and Science in Sports and Exercise",
issn = "0195-9131",
publisher = "Lippincott Williams & Wilkins",
number = "4",

}

RIS

TY - JOUR

T1 - Neuromuscular Electrical Stimulation Preserves Leg Lean Mass in Geriatric Patients

AU - Karlsen, Anders

AU - Cullum, Christopher Kjaer

AU - Norheim, Kristoffer Larsen

AU - Scheel, Frederik Ulrik

AU - Zinglersen, Amanda Hempel

AU - Vahlgren, Julie

AU - Schjerling, Peter

AU - Kjaer, Michael

AU - Mackey, Abigail L.

PY - 2020

Y1 - 2020

N2 - Aim To examine changes in lean mass during hospitalization in geriatric patients and the effect of muscle activation by neuromuscular electrical stimulation. Methods Thirteen patients (69-94 years) at a geriatric ward completed tests at hospital admission (day 2-3) and discharge (day 8-10). One leg received daily stimulation of the knee extensors while the other leg served as a control leg. Lean mass was evaluated by DEXA scans and muscle thickness by ultrasound scans. Muscle biopsies were collected from both legs at admission and discharge in 9 patients and analyzed for fibre size, satellite cell number and activation and expression of genes associated with muscle protein synthesis and breakdown, connective tissue and cellular stress. Results The relative decline in leg lean mass and midthigh region lean mass was larger in the control (-2.8±1.5%) vs. the stimulated leg (-0.5±1.4%, p

AB - Aim To examine changes in lean mass during hospitalization in geriatric patients and the effect of muscle activation by neuromuscular electrical stimulation. Methods Thirteen patients (69-94 years) at a geriatric ward completed tests at hospital admission (day 2-3) and discharge (day 8-10). One leg received daily stimulation of the knee extensors while the other leg served as a control leg. Lean mass was evaluated by DEXA scans and muscle thickness by ultrasound scans. Muscle biopsies were collected from both legs at admission and discharge in 9 patients and analyzed for fibre size, satellite cell number and activation and expression of genes associated with muscle protein synthesis and breakdown, connective tissue and cellular stress. Results The relative decline in leg lean mass and midthigh region lean mass was larger in the control (-2.8±1.5%) vs. the stimulated leg (-0.5±1.4%, p

KW - Muscle Atrophy

KW - Muscle Activation

KW - Neuromuscular Electrical Stimulation

KW - Satellite Cells

KW - Gene Expression

U2 - 10.1249/MSS.0000000000002191

DO - 10.1249/MSS.0000000000002191

M3 - Journal article

C2 - 31688649

VL - 52

SP - 773

EP - 784

JO - Medicine and Science in Sports and Exercise

JF - Medicine and Science in Sports and Exercise

SN - 0195-9131

IS - 4

ER -

ID: 229730061