Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Linking neuroethology to the chemical biology of natural products : interactions between cone snails and their fish prey, a case study. / Olivera, Baldomero M.; Raghuraman, Shrinivasan; Schmidt, Eric W.; Safavi-Hemami, Helena.

I: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, Bind 203, Nr. 9, 10.2017, s. 717-735.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Olivera, BM, Raghuraman, S, Schmidt, EW & Safavi-Hemami, H 2017, 'Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study', Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, bind 203, nr. 9, s. 717-735. https://doi.org/10.1007/s00359-017-1183-7

APA

Olivera, B. M., Raghuraman, S., Schmidt, E. W., & Safavi-Hemami, H. (2017). Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 203(9), 717-735. https://doi.org/10.1007/s00359-017-1183-7

Vancouver

Olivera BM, Raghuraman S, Schmidt EW, Safavi-Hemami H. Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 2017 okt.;203(9):717-735. https://doi.org/10.1007/s00359-017-1183-7

Author

Olivera, Baldomero M. ; Raghuraman, Shrinivasan ; Schmidt, Eric W. ; Safavi-Hemami, Helena. / Linking neuroethology to the chemical biology of natural products : interactions between cone snails and their fish prey, a case study. I: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 2017 ; Bind 203, Nr. 9. s. 717-735.

Bibtex

@article{5f9505bd65c04f6eb01bb87af6439498,
title = "Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study",
abstract = "From a biological perspective, a natural product can be defined as a compound evolved by an organism for chemical interactions with another organism including prey, predator, competitor, pathogen, symbiont or host. Natural products hold tremendous potential as drug leads and have been extensively studied by chemists and biochemists in the pharmaceutical industry. However, the biological purpose for which a natural product evolved is rarely addressed. By focusing on a well-studied group of natural products—venom components from predatory marine cone snails—this review provides a rationale for why a better understanding of the evolution, biology and biochemistry of natural products will facilitate both neuroscience and the potential for drug leads. The larger goal is to establish a new sub-discipline in the broader field of neuroethology that we refer to as “Chemical Neuroethology”, linking the substantial work carried out by chemists on natural products with accelerating advances in neuroethology.",
keywords = "Chemical neuroethology, Cone snail venom, Natural products, Toxin cabals",
author = "Olivera, {Baldomero M.} and Shrinivasan Raghuraman and Schmidt, {Eric W.} and Helena Safavi-Hemami",
year = "2017",
month = oct,
doi = "10.1007/s00359-017-1183-7",
language = "English",
volume = "203",
pages = "717--735",
journal = "Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology",
issn = "0340-7594",
publisher = "Springer",
number = "9",

}

RIS

TY - JOUR

T1 - Linking neuroethology to the chemical biology of natural products

T2 - interactions between cone snails and their fish prey, a case study

AU - Olivera, Baldomero M.

AU - Raghuraman, Shrinivasan

AU - Schmidt, Eric W.

AU - Safavi-Hemami, Helena

PY - 2017/10

Y1 - 2017/10

N2 - From a biological perspective, a natural product can be defined as a compound evolved by an organism for chemical interactions with another organism including prey, predator, competitor, pathogen, symbiont or host. Natural products hold tremendous potential as drug leads and have been extensively studied by chemists and biochemists in the pharmaceutical industry. However, the biological purpose for which a natural product evolved is rarely addressed. By focusing on a well-studied group of natural products—venom components from predatory marine cone snails—this review provides a rationale for why a better understanding of the evolution, biology and biochemistry of natural products will facilitate both neuroscience and the potential for drug leads. The larger goal is to establish a new sub-discipline in the broader field of neuroethology that we refer to as “Chemical Neuroethology”, linking the substantial work carried out by chemists on natural products with accelerating advances in neuroethology.

AB - From a biological perspective, a natural product can be defined as a compound evolved by an organism for chemical interactions with another organism including prey, predator, competitor, pathogen, symbiont or host. Natural products hold tremendous potential as drug leads and have been extensively studied by chemists and biochemists in the pharmaceutical industry. However, the biological purpose for which a natural product evolved is rarely addressed. By focusing on a well-studied group of natural products—venom components from predatory marine cone snails—this review provides a rationale for why a better understanding of the evolution, biology and biochemistry of natural products will facilitate both neuroscience and the potential for drug leads. The larger goal is to establish a new sub-discipline in the broader field of neuroethology that we refer to as “Chemical Neuroethology”, linking the substantial work carried out by chemists on natural products with accelerating advances in neuroethology.

KW - Chemical neuroethology

KW - Cone snail venom

KW - Natural products

KW - Toxin cabals

UR - http://www.scopus.com/inward/record.url?scp=85019771075&partnerID=8YFLogxK

U2 - 10.1007/s00359-017-1183-7

DO - 10.1007/s00359-017-1183-7

M3 - Review

C2 - 28551870

AN - SCOPUS:85019771075

VL - 203

SP - 717

EP - 735

JO - Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology

JF - Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology

SN - 0340-7594

IS - 9

ER -

ID: 184068531