Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes

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Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes. / Sejling, Anne-Sophie; Lange, Kai H W; Frandsen, Christian S; Diemar, Sarah S; Tarnow, Lise; Faber, Jens; Holst, Jens J; Hartmann, Bolette; Hilsted, Linda; Kjaer, Troels W; Juhl, Claus B; Thorsteinsson, Birger; Pedersen-Bjergaard, Ulrik.

I: Diabetologia, Bind 58, 2015, s. 1898–1906.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Sejling, A-S, Lange, KHW, Frandsen, CS, Diemar, SS, Tarnow, L, Faber, J, Holst, JJ, Hartmann, B, Hilsted, L, Kjaer, TW, Juhl, CB, Thorsteinsson, B & Pedersen-Bjergaard, U 2015, 'Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes', Diabetologia, bind 58, s. 1898–1906. https://doi.org/10.1007/s00125-015-3616-6

APA

Sejling, A-S., Lange, K. H. W., Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, J., Holst, J. J., Hartmann, B., Hilsted, L., Kjaer, T. W., Juhl, C. B., Thorsteinsson, B., & Pedersen-Bjergaard, U. (2015). Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes. Diabetologia, 58, 1898–1906. https://doi.org/10.1007/s00125-015-3616-6

Vancouver

Sejling A-S, Lange KHW, Frandsen CS, Diemar SS, Tarnow L, Faber J o.a. Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes. Diabetologia. 2015;58:1898–1906. https://doi.org/10.1007/s00125-015-3616-6

Author

Sejling, Anne-Sophie ; Lange, Kai H W ; Frandsen, Christian S ; Diemar, Sarah S ; Tarnow, Lise ; Faber, Jens ; Holst, Jens J ; Hartmann, Bolette ; Hilsted, Linda ; Kjaer, Troels W ; Juhl, Claus B ; Thorsteinsson, Birger ; Pedersen-Bjergaard, Ulrik. / Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes. I: Diabetologia. 2015 ; Bind 58. s. 1898–1906.

Bibtex

@article{6679e2389ead4239abab1a0bea091647,
title = "Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes",
abstract = "AIMS/HYPOTHESIS: Hypoglycaemia is associated with reduced skin temperature (Ts). We studied whether infrared thermography can detect Ts changes during hypoglycaemia in patients with type 1 diabetes and how the Ts response differs between patients with normal hypoglycaemia awareness and hypoglycaemia unawareness.METHODS: Twenty-four patients with type 1 diabetes (ten aware, 14 unaware) were studied during normoglycaemia (5.0-6.0 mmol/l), hypoglycaemia (2.0-2.5 mmol/l) and during recovery from hypoglycaemia (5.0-6.0 mmol/l) using hyperinsulinaemic glucose clamping. During each 1 h phase, Ts was measured twice by infrared thermography imaging in pre-defined areas (nose, glabella and the five left fingertips), symptoms of hypoglycaemia were scored and blood was sampled.RESULTS: Ts decreased during hypoglycaemia on the nose and glabella. The highest decrements were recorded on the nose (aware: -2.6°C, unaware: -1.1°C). In aware patients, the differences in temperature were statistically significant on both nose and glabella, whereas there was only a trend in the unaware group. There was a significant difference in hypoglycaemia-induced temperature changes between the groups. Patients in the aware group had higher hypoglycaemia symptom scores and higher adrenaline (epinephrine) levels during hypoglycaemia.CONCLUSIONS/INTERPRETATION: The hypoglycaemia-associated decrement in Ts can be assessed by infrared thermography and is larger in patients with normal hypoglycaemia awareness compared with unaware patients.",
author = "Anne-Sophie Sejling and Lange, {Kai H W} and Frandsen, {Christian S} and Diemar, {Sarah S} and Lise Tarnow and Jens Faber and Holst, {Jens J} and Bolette Hartmann and Linda Hilsted and Kjaer, {Troels W} and Juhl, {Claus B} and Birger Thorsteinsson and Ulrik Pedersen-Bjergaard",
year = "2015",
doi = "10.1007/s00125-015-3616-6",
language = "English",
volume = "58",
pages = "1898–1906",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes

AU - Sejling, Anne-Sophie

AU - Lange, Kai H W

AU - Frandsen, Christian S

AU - Diemar, Sarah S

AU - Tarnow, Lise

AU - Faber, Jens

AU - Holst, Jens J

AU - Hartmann, Bolette

AU - Hilsted, Linda

AU - Kjaer, Troels W

AU - Juhl, Claus B

AU - Thorsteinsson, Birger

AU - Pedersen-Bjergaard, Ulrik

PY - 2015

Y1 - 2015

N2 - AIMS/HYPOTHESIS: Hypoglycaemia is associated with reduced skin temperature (Ts). We studied whether infrared thermography can detect Ts changes during hypoglycaemia in patients with type 1 diabetes and how the Ts response differs between patients with normal hypoglycaemia awareness and hypoglycaemia unawareness.METHODS: Twenty-four patients with type 1 diabetes (ten aware, 14 unaware) were studied during normoglycaemia (5.0-6.0 mmol/l), hypoglycaemia (2.0-2.5 mmol/l) and during recovery from hypoglycaemia (5.0-6.0 mmol/l) using hyperinsulinaemic glucose clamping. During each 1 h phase, Ts was measured twice by infrared thermography imaging in pre-defined areas (nose, glabella and the five left fingertips), symptoms of hypoglycaemia were scored and blood was sampled.RESULTS: Ts decreased during hypoglycaemia on the nose and glabella. The highest decrements were recorded on the nose (aware: -2.6°C, unaware: -1.1°C). In aware patients, the differences in temperature were statistically significant on both nose and glabella, whereas there was only a trend in the unaware group. There was a significant difference in hypoglycaemia-induced temperature changes between the groups. Patients in the aware group had higher hypoglycaemia symptom scores and higher adrenaline (epinephrine) levels during hypoglycaemia.CONCLUSIONS/INTERPRETATION: The hypoglycaemia-associated decrement in Ts can be assessed by infrared thermography and is larger in patients with normal hypoglycaemia awareness compared with unaware patients.

AB - AIMS/HYPOTHESIS: Hypoglycaemia is associated with reduced skin temperature (Ts). We studied whether infrared thermography can detect Ts changes during hypoglycaemia in patients with type 1 diabetes and how the Ts response differs between patients with normal hypoglycaemia awareness and hypoglycaemia unawareness.METHODS: Twenty-four patients with type 1 diabetes (ten aware, 14 unaware) were studied during normoglycaemia (5.0-6.0 mmol/l), hypoglycaemia (2.0-2.5 mmol/l) and during recovery from hypoglycaemia (5.0-6.0 mmol/l) using hyperinsulinaemic glucose clamping. During each 1 h phase, Ts was measured twice by infrared thermography imaging in pre-defined areas (nose, glabella and the five left fingertips), symptoms of hypoglycaemia were scored and blood was sampled.RESULTS: Ts decreased during hypoglycaemia on the nose and glabella. The highest decrements were recorded on the nose (aware: -2.6°C, unaware: -1.1°C). In aware patients, the differences in temperature were statistically significant on both nose and glabella, whereas there was only a trend in the unaware group. There was a significant difference in hypoglycaemia-induced temperature changes between the groups. Patients in the aware group had higher hypoglycaemia symptom scores and higher adrenaline (epinephrine) levels during hypoglycaemia.CONCLUSIONS/INTERPRETATION: The hypoglycaemia-associated decrement in Ts can be assessed by infrared thermography and is larger in patients with normal hypoglycaemia awareness compared with unaware patients.

U2 - 10.1007/s00125-015-3616-6

DO - 10.1007/s00125-015-3616-6

M3 - Journal article

C2 - 25985748

VL - 58

SP - 1898

EP - 1906

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

ER -

ID: 149078651