Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Morten Bækgaard Thomsen, S Cora Verduyn, Milan Stengl, Jet D M Beekman, Geert de Pater, Jurren van Opstal, Paul G A Volders, Marc A Vos

Identification of patients at risk for drug-induced torsades de pointes arrhythmia (TdP) is difficult. Increased temporal lability of repolarization has been suggested as being valuable to predict proarrhythmia. The predictive value of different repolarization parameters, including beat-to-beat variability of repolarization (BVR), was compared in this serial investigation in dogs with chronic AV block.
OriginalsprogEngelsk
TidsskriftCirculation
Vol/bind110
Udgave nummer16
Sider (fra-til)2453-9
Antal sider7
ISSN0009-7322
DOI
StatusUdgivet - 19 okt. 2004

ID: 45965630