In vivo human lipolytic activity in preperitoneal and subdivisions of subcutaneous abdominal adipose tissue
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In vivo human lipolytic activity in preperitoneal and subdivisions of subcutaneous abdominal adipose tissue. / Enevoldsen, L H; Simonsen, L; Stallknecht, B; Galbo, H; Bülow, J.
I: American Journal of Physiology: Endocrinology and Metabolism, Bind 281, Nr. 5, 2001, s. E1110-4.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - In vivo human lipolytic activity in preperitoneal and subdivisions of subcutaneous abdominal adipose tissue
AU - Enevoldsen, L H
AU - Simonsen, L
AU - Stallknecht, B
AU - Galbo, H
AU - Bülow, J
N1 - Keywords: Abdomen; Adipose Tissue; Adult; Blood Flow Velocity; Epinephrine; Glycerol; Humans; Infusions, Intravenous; Lipolysis; Male; Microdialysis; Peritoneum; Xenon Radioisotopes
PY - 2001
Y1 - 2001
N2 - We studied eight normal-weight male subjects to examine whether the lipolytic rate of deep subcutaneous and preperitoneal adipose tissues differs from that of superficial abdominal subcutaneous adipose tissue. The lipolytic rates in the superficial anterior and deep posterior subcutaneous abdominal adipose tissues and in the preperitoneal adipose tissue in the round ligament were measured by microdialysis and (133)Xe washout under basal, postabsorptive conditions and during intravenous epinephrine infusion (0.15 nmol. kg(-1). min(-1)). Both in the basal state and during epinephrine stimulation, the superficial subcutaneous adipose tissue had higher interstitial glycerol concentrations than the two other depots. Similarly, the calculated glycerol outputs from the superficial depot were significantly higher than those from the deep subcutaneous and the preperitoneal depots. Thus, it is concluded that the lipolytic rate of the superficial subcutaneous adipose tissue on the anterior abdominal wall is higher than that of the deep subcutaneous adipose tissue on the posterior abdominal wall and that of the preperitoneal adipose tissue in the round ligament.
AB - We studied eight normal-weight male subjects to examine whether the lipolytic rate of deep subcutaneous and preperitoneal adipose tissues differs from that of superficial abdominal subcutaneous adipose tissue. The lipolytic rates in the superficial anterior and deep posterior subcutaneous abdominal adipose tissues and in the preperitoneal adipose tissue in the round ligament were measured by microdialysis and (133)Xe washout under basal, postabsorptive conditions and during intravenous epinephrine infusion (0.15 nmol. kg(-1). min(-1)). Both in the basal state and during epinephrine stimulation, the superficial subcutaneous adipose tissue had higher interstitial glycerol concentrations than the two other depots. Similarly, the calculated glycerol outputs from the superficial depot were significantly higher than those from the deep subcutaneous and the preperitoneal depots. Thus, it is concluded that the lipolytic rate of the superficial subcutaneous adipose tissue on the anterior abdominal wall is higher than that of the deep subcutaneous adipose tissue on the posterior abdominal wall and that of the preperitoneal adipose tissue in the round ligament.
M3 - Journal article
C2 - 11595670
VL - 281
SP - E1110-4
JO - American Journal of Physiology - Endocrinology and Metabolism
JF - American Journal of Physiology - Endocrinology and Metabolism
SN - 0193-1849
IS - 5
ER -
ID: 173351