Functional modeling of neural-glial interaction

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Standard

Functional modeling of neural-glial interaction. / Postnov, D E; Ryazanova, L S; Sosnovtseva, Olga.

I: BioSystems, Bind 89, Nr. 1-3, 2007, s. 84-91.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Postnov, DE, Ryazanova, LS & Sosnovtseva, O 2007, 'Functional modeling of neural-glial interaction', BioSystems, bind 89, nr. 1-3, s. 84-91. https://doi.org/10.1016/j.biosystems.2006.04.012

APA

Postnov, D. E., Ryazanova, L. S., & Sosnovtseva, O. (2007). Functional modeling of neural-glial interaction. BioSystems, 89(1-3), 84-91. https://doi.org/10.1016/j.biosystems.2006.04.012

Vancouver

Postnov DE, Ryazanova LS, Sosnovtseva O. Functional modeling of neural-glial interaction. BioSystems. 2007;89(1-3):84-91. https://doi.org/10.1016/j.biosystems.2006.04.012

Author

Postnov, D E ; Ryazanova, L S ; Sosnovtseva, Olga. / Functional modeling of neural-glial interaction. I: BioSystems. 2007 ; Bind 89, Nr. 1-3. s. 84-91.

Bibtex

@article{797d53a4050748dc93fdb41de87cd85d,
title = "Functional modeling of neural-glial interaction",
abstract = "We propose a generalized mathematical model for a small neural-glial ensemble. The model incorporates subunits of the tripartite synapse that includes a presynaptic neuron, the synaptic terminal itself, a postsynaptic neuron, and a glial cell. The glial cell is assumed to be activated via two different pathways: (i) the fast increase of intercellular [K(+)] produced by the spiking activity of the postsynaptic neuron, and (ii) the slow production of a mediator triggered by the synaptic activity. Our model predicts the long-term potentiation of the postsynaptic neuron as well as various [Ca(2+)] transients in response to the activation of different pathways.",
keywords = "Long-Term Potentiation, Models, Neurological, Neuroglia, Neurons, Potassium",
author = "Postnov, {D E} and Ryazanova, {L S} and Olga Sosnovtseva",
year = "2007",
doi = "10.1016/j.biosystems.2006.04.012",
language = "English",
volume = "89",
pages = "84--91",
journal = "BioSystems",
issn = "0303-2647",
publisher = "Elsevier",
number = "1-3",

}

RIS

TY - JOUR

T1 - Functional modeling of neural-glial interaction

AU - Postnov, D E

AU - Ryazanova, L S

AU - Sosnovtseva, Olga

PY - 2007

Y1 - 2007

N2 - We propose a generalized mathematical model for a small neural-glial ensemble. The model incorporates subunits of the tripartite synapse that includes a presynaptic neuron, the synaptic terminal itself, a postsynaptic neuron, and a glial cell. The glial cell is assumed to be activated via two different pathways: (i) the fast increase of intercellular [K(+)] produced by the spiking activity of the postsynaptic neuron, and (ii) the slow production of a mediator triggered by the synaptic activity. Our model predicts the long-term potentiation of the postsynaptic neuron as well as various [Ca(2+)] transients in response to the activation of different pathways.

AB - We propose a generalized mathematical model for a small neural-glial ensemble. The model incorporates subunits of the tripartite synapse that includes a presynaptic neuron, the synaptic terminal itself, a postsynaptic neuron, and a glial cell. The glial cell is assumed to be activated via two different pathways: (i) the fast increase of intercellular [K(+)] produced by the spiking activity of the postsynaptic neuron, and (ii) the slow production of a mediator triggered by the synaptic activity. Our model predicts the long-term potentiation of the postsynaptic neuron as well as various [Ca(2+)] transients in response to the activation of different pathways.

KW - Long-Term Potentiation

KW - Models, Neurological

KW - Neuroglia

KW - Neurons

KW - Potassium

U2 - 10.1016/j.biosystems.2006.04.012

DO - 10.1016/j.biosystems.2006.04.012

M3 - Journal article

C2 - 17320272

VL - 89

SP - 84

EP - 91

JO - BioSystems

JF - BioSystems

SN - 0303-2647

IS - 1-3

ER -

ID: 33812538