Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children

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Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. / Munch-Andersen, Thor; Sorensen, Kaspar; Aachmann-Andersen, Niels-Jacob; Aksglaede, Lise; Juul, Anders; Helge, Jørn Wulff.

I: International Journal of Circumpolar Health, Bind 72, 21458, 2013, s. 1-7.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Munch-Andersen, T, Sorensen, K, Aachmann-Andersen, N-J, Aksglaede, L, Juul, A & Helge, JW 2013, 'Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children', International Journal of Circumpolar Health, bind 72, 21458, s. 1-7. https://doi.org/10.3402/ijch.v72i0.21458

APA

Munch-Andersen, T., Sorensen, K., Aachmann-Andersen, N-J., Aksglaede, L., Juul, A., & Helge, J. W. (2013). Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. International Journal of Circumpolar Health, 72, 1-7. [21458]. https://doi.org/10.3402/ijch.v72i0.21458

Vancouver

Munch-Andersen T, Sorensen K, Aachmann-Andersen N-J, Aksglaede L, Juul A, Helge JW. Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. International Journal of Circumpolar Health. 2013;72:1-7. 21458. https://doi.org/10.3402/ijch.v72i0.21458

Author

Munch-Andersen, Thor ; Sorensen, Kaspar ; Aachmann-Andersen, Niels-Jacob ; Aksglaede, Lise ; Juul, Anders ; Helge, Jørn Wulff. / Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. I: International Journal of Circumpolar Health. 2013 ; Bind 72. s. 1-7.

Bibtex

@article{97c60addc15245f7bba055a31c66eacf,
title = "Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children",
abstract = "Objective. In a recent study, we found that Greenlandic Inuit children had a more adverse metabolic profile than Danish children. Aerobic fitness and adiposity could only partly account for the differences. Therefore, we set out to evaluate and compare plasma leptin and adiponectin levels in Danish and Inuit children.Methods. In total, 187 Inuit and 132 Danish children (5.7–17.1 years) had examinations of anthropometrics, body fat content, pubertal staging, fasting blood and aerobic fitness.Results. Plasma leptin was higher in Danish boys [3,774 (4,741–3,005)] [pg/mL unadjusted geometric mean (95{\%} CI)] compared to both northern [2,076 (2,525–1,706)] (p<0.001) and southern (2,515 (3,137–2,016)) (p<0.001) living Inuit boys and higher in Danish girls [6,988 (8,353–5,847)] compared to southern living Inuit girls [4,910 (6,370–3,785)] (p=0.021) and tended to be higher compared to northern living Inuit girls [5,131 (6,444–4,085)] (p=0.052). Plasma adiponectin was higher for both Danish boys [22,359 (2,573–19,428)] [ng/mL unadjusted geometric mean (95{\%} CI)] and girls [26,609 (28,994–24,420)] compared to southern living Inuit boys [15,306 (18,406–12,728)] and girls [18,864 (22,640–15,717)] (both p<0.001), respectively. All differences remained after adjustment for body fat percentage (BF{\%}), aerobic fitness, age and puberty. The leptin/adiponectin ratio was higher in Danish boys and tended to be higher in Danish girls compared to northern living Inuit boys and girls, respectively. These differences were eliminated after adjustment for BF{\%}, aerobic fitness, age and puberty.Conclusions. In contrast to our hypothesis, plasma leptin was higher in Danish children despite a more healthy metabolic profile compared to Inuit children. As expected, plasma adiponectin was lowest in Inuit children with the most adverse metabolic profile.",
keywords = "leptin, adiponectin, children, metabolic syndrome, ethnic differences, Inuit, leptin/adiponectin ratio",
author = "Thor Munch-Andersen and Kaspar Sorensen and Niels-Jacob Aachmann-Andersen and Lise Aksglaede and Anders Juul and Helge, {J{\o}rn Wulff}",
year = "2013",
doi = "10.3402/ijch.v72i0.21458",
language = "English",
volume = "72",
pages = "1--7",
journal = "International Journal of Circumpolar Health",
issn = "1239-9736",
publisher = "International Association of Circumpolar Health Publishers",

}

RIS

TY - JOUR

T1 - Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children

AU - Munch-Andersen, Thor

AU - Sorensen, Kaspar

AU - Aachmann-Andersen, Niels-Jacob

AU - Aksglaede, Lise

AU - Juul, Anders

AU - Helge, Jørn Wulff

PY - 2013

Y1 - 2013

N2 - Objective. In a recent study, we found that Greenlandic Inuit children had a more adverse metabolic profile than Danish children. Aerobic fitness and adiposity could only partly account for the differences. Therefore, we set out to evaluate and compare plasma leptin and adiponectin levels in Danish and Inuit children.Methods. In total, 187 Inuit and 132 Danish children (5.7–17.1 years) had examinations of anthropometrics, body fat content, pubertal staging, fasting blood and aerobic fitness.Results. Plasma leptin was higher in Danish boys [3,774 (4,741–3,005)] [pg/mL unadjusted geometric mean (95% CI)] compared to both northern [2,076 (2,525–1,706)] (p<0.001) and southern (2,515 (3,137–2,016)) (p<0.001) living Inuit boys and higher in Danish girls [6,988 (8,353–5,847)] compared to southern living Inuit girls [4,910 (6,370–3,785)] (p=0.021) and tended to be higher compared to northern living Inuit girls [5,131 (6,444–4,085)] (p=0.052). Plasma adiponectin was higher for both Danish boys [22,359 (2,573–19,428)] [ng/mL unadjusted geometric mean (95% CI)] and girls [26,609 (28,994–24,420)] compared to southern living Inuit boys [15,306 (18,406–12,728)] and girls [18,864 (22,640–15,717)] (both p<0.001), respectively. All differences remained after adjustment for body fat percentage (BF%), aerobic fitness, age and puberty. The leptin/adiponectin ratio was higher in Danish boys and tended to be higher in Danish girls compared to northern living Inuit boys and girls, respectively. These differences were eliminated after adjustment for BF%, aerobic fitness, age and puberty.Conclusions. In contrast to our hypothesis, plasma leptin was higher in Danish children despite a more healthy metabolic profile compared to Inuit children. As expected, plasma adiponectin was lowest in Inuit children with the most adverse metabolic profile.

AB - Objective. In a recent study, we found that Greenlandic Inuit children had a more adverse metabolic profile than Danish children. Aerobic fitness and adiposity could only partly account for the differences. Therefore, we set out to evaluate and compare plasma leptin and adiponectin levels in Danish and Inuit children.Methods. In total, 187 Inuit and 132 Danish children (5.7–17.1 years) had examinations of anthropometrics, body fat content, pubertal staging, fasting blood and aerobic fitness.Results. Plasma leptin was higher in Danish boys [3,774 (4,741–3,005)] [pg/mL unadjusted geometric mean (95% CI)] compared to both northern [2,076 (2,525–1,706)] (p<0.001) and southern (2,515 (3,137–2,016)) (p<0.001) living Inuit boys and higher in Danish girls [6,988 (8,353–5,847)] compared to southern living Inuit girls [4,910 (6,370–3,785)] (p=0.021) and tended to be higher compared to northern living Inuit girls [5,131 (6,444–4,085)] (p=0.052). Plasma adiponectin was higher for both Danish boys [22,359 (2,573–19,428)] [ng/mL unadjusted geometric mean (95% CI)] and girls [26,609 (28,994–24,420)] compared to southern living Inuit boys [15,306 (18,406–12,728)] and girls [18,864 (22,640–15,717)] (both p<0.001), respectively. All differences remained after adjustment for body fat percentage (BF%), aerobic fitness, age and puberty. The leptin/adiponectin ratio was higher in Danish boys and tended to be higher in Danish girls compared to northern living Inuit boys and girls, respectively. These differences were eliminated after adjustment for BF%, aerobic fitness, age and puberty.Conclusions. In contrast to our hypothesis, plasma leptin was higher in Danish children despite a more healthy metabolic profile compared to Inuit children. As expected, plasma adiponectin was lowest in Inuit children with the most adverse metabolic profile.

KW - leptin

KW - adiponectin

KW - children

KW - metabolic syndrome

KW - ethnic differences

KW - Inuit

KW - leptin/adiponectin ratio

U2 - 10.3402/ijch.v72i0.21458

DO - 10.3402/ijch.v72i0.21458

M3 - Journal article

VL - 72

SP - 1

EP - 7

JO - International Journal of Circumpolar Health

JF - International Journal of Circumpolar Health

SN - 1239-9736

M1 - 21458

ER -

ID: 117869431