Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels

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Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels. / Larsen, A P; Bentzen, Bo Hjorth; Grunnet, M.

I: British Journal of Pharmacology, Bind 161, Nr. 3, 10.2010, s. 614-28.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Larsen, AP, Bentzen, BH & Grunnet, M 2010, 'Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels', British Journal of Pharmacology, bind 161, nr. 3, s. 614-28. https://doi.org/10.1111/j.1476-5381.2010.00897.x

APA

Larsen, A. P., Bentzen, B. H., & Grunnet, M. (2010). Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels. British Journal of Pharmacology, 161(3), 614-28. https://doi.org/10.1111/j.1476-5381.2010.00897.x

Vancouver

Larsen AP, Bentzen BH, Grunnet M. Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels. British Journal of Pharmacology. 2010 okt.;161(3):614-28. https://doi.org/10.1111/j.1476-5381.2010.00897.x

Author

Larsen, A P ; Bentzen, Bo Hjorth ; Grunnet, M. / Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels. I: British Journal of Pharmacology. 2010 ; Bind 161, Nr. 3. s. 614-28.

Bibtex

@article{1e717974735a412dba9fff9c6d799ce5,
title = "Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels",
abstract = "K(v)11.1 channels are involved in regulating cellular excitability in various tissues including brain, heart and smooth muscle. In these tissues, at least two isoforms, K(v)11.1a and K(v)11.1b, with different kinetics, are expressed. K(v)11.1 activators are potential therapeutic agents, but their effects have only been tested on the K(v)11.1a isoform. In this study, the effects of two different K(v)11.1 activators, NS1643 and RPR260243, were characterized on K(v)11.1a and K(v)11.1b channels.",
keywords = "Animals, Cresols, Ether-A-Go-Go Potassium Channels, Membrane Potentials, Oocytes, Patch-Clamp Techniques, Phenylurea Compounds, Piperidines, Protein Isoforms, Quinolines, Transfection, Xenopus laevis",
author = "Larsen, {A P} and Bentzen, {Bo Hjorth} and M Grunnet",
year = "2010",
month = oct,
doi = "10.1111/j.1476-5381.2010.00897.x",
language = "English",
volume = "161",
pages = "614--28",
journal = "British Journal of Pharmacology",
issn = "0007-1188",
publisher = "Wiley",
number = "3",

}

RIS

TY - JOUR

T1 - Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels

AU - Larsen, A P

AU - Bentzen, Bo Hjorth

AU - Grunnet, M

PY - 2010/10

Y1 - 2010/10

N2 - K(v)11.1 channels are involved in regulating cellular excitability in various tissues including brain, heart and smooth muscle. In these tissues, at least two isoforms, K(v)11.1a and K(v)11.1b, with different kinetics, are expressed. K(v)11.1 activators are potential therapeutic agents, but their effects have only been tested on the K(v)11.1a isoform. In this study, the effects of two different K(v)11.1 activators, NS1643 and RPR260243, were characterized on K(v)11.1a and K(v)11.1b channels.

AB - K(v)11.1 channels are involved in regulating cellular excitability in various tissues including brain, heart and smooth muscle. In these tissues, at least two isoforms, K(v)11.1a and K(v)11.1b, with different kinetics, are expressed. K(v)11.1 activators are potential therapeutic agents, but their effects have only been tested on the K(v)11.1a isoform. In this study, the effects of two different K(v)11.1 activators, NS1643 and RPR260243, were characterized on K(v)11.1a and K(v)11.1b channels.

KW - Animals

KW - Cresols

KW - Ether-A-Go-Go Potassium Channels

KW - Membrane Potentials

KW - Oocytes

KW - Patch-Clamp Techniques

KW - Phenylurea Compounds

KW - Piperidines

KW - Protein Isoforms

KW - Quinolines

KW - Transfection

KW - Xenopus laevis

U2 - 10.1111/j.1476-5381.2010.00897.x

DO - 10.1111/j.1476-5381.2010.00897.x

M3 - Journal article

C2 - 20880400

VL - 161

SP - 614

EP - 628

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 0007-1188

IS - 3

ER -

ID: 45080993