Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium
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Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium. / Tam, C S; Berthoud, H-R; Bueter, M; Chakravarthy, M V; Geliebter, A; Hajnal, A; Holst, Jens Juul; Kaplan, L; Pories, W; Raybould, H; Seeley, R; Strader, A; Ravussin, E.
I: Obesity Reviews, Bind 12, Nr. 11, 11.2011, s. 984-94.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Could the mechanisms of bariatric surgery hold the key for novel therapies?
T2 - report from a Pennington Scientific Symposium
AU - Tam, C S
AU - Berthoud, H-R
AU - Bueter, M
AU - Chakravarthy, M V
AU - Geliebter, A
AU - Hajnal, A
AU - Holst, Jens Juul
AU - Kaplan, L
AU - Pories, W
AU - Raybould, H
AU - Seeley, R
AU - Strader, A
AU - Ravussin, E
N1 - © 2011 The Authors. obesity reviews © 2011 International Association for the Study of Obesity.
PY - 2011/11
Y1 - 2011/11
N2 - Bariatric surgery is the most effective method for promoting dramatic and durable weight loss in morbidly obese subjects. Furthermore, type 2 diabetes is resolved in over 80% of patients. The mechanisms behind the amelioration in metabolic abnormalities are largely unknown but may be due to changes in energy metabolism, gut peptides and food preference. The goal of this meeting was to review the latest research to better understand the mechanisms behind the 'magic' of bariatric surgery. Replication of these effects in a non-surgical manner remains one of the ultimate challenges for the treatment of obesity and diabetes. Promising data on energy metabolism, gastrointestinal physiology, hedonic response and food intake were reviewed and discussed.
AB - Bariatric surgery is the most effective method for promoting dramatic and durable weight loss in morbidly obese subjects. Furthermore, type 2 diabetes is resolved in over 80% of patients. The mechanisms behind the amelioration in metabolic abnormalities are largely unknown but may be due to changes in energy metabolism, gut peptides and food preference. The goal of this meeting was to review the latest research to better understand the mechanisms behind the 'magic' of bariatric surgery. Replication of these effects in a non-surgical manner remains one of the ultimate challenges for the treatment of obesity and diabetes. Promising data on energy metabolism, gastrointestinal physiology, hedonic response and food intake were reviewed and discussed.
KW - Bariatric Surgery
KW - Energy Metabolism
KW - Ghrelin
KW - Glucagon-Like Peptide 1
KW - Humans
KW - Obesity, Morbid
KW - Peptide YY
KW - Weight Loss
U2 - 10.1111/j.1467-789X.2011.00902.x
DO - 10.1111/j.1467-789X.2011.00902.x
M3 - Journal article
C2 - 21729236
VL - 12
SP - 984
EP - 994
JO - Obesity Reviews
JF - Obesity Reviews
SN - 1467-7881
IS - 11
ER -
ID: 45841808