Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers

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Standard

Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers. / Ralston, E; Ploug, Thorkil.

I: Experimental Cell Research, Bind 246, Nr. 2, 01.02.1999, s. 510-5.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Ralston, E & Ploug, T 1999, 'Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers', Experimental Cell Research, bind 246, nr. 2, s. 510-5. https://doi.org/10.1006/excr.1998.4305

APA

Ralston, E., & Ploug, T. (1999). Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers. Experimental Cell Research, 246(2), 510-5. https://doi.org/10.1006/excr.1998.4305

Vancouver

Ralston E, Ploug T. Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers. Experimental Cell Research. 1999 feb. 1;246(2):510-5. https://doi.org/10.1006/excr.1998.4305

Author

Ralston, E ; Ploug, Thorkil. / Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers. I: Experimental Cell Research. 1999 ; Bind 246, Nr. 2. s. 510-5.

Bibtex

@article{522c01dfdf5e46c39eb7f00dcfd205f7,
title = "Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers",
abstract = "Caveolae are abundant in skeletal muscle and their coat contains a specific isoform of caveolin, caveolin-3. It has been suggested that during muscle development, caveolin-3 is associated with the T-tubules, but that in adult muscle it is found on the plasma membrane only. We have studied the distribution of caveolin-3 in single skeletal muscle fibers from adult rat soleus by confocal immunofluorescence and by immunogold electron microscopy. We found that caveolin-3 occurs at the highest density on the plasma membrane but is also present in the core of the fibers, at the I-band/A-band interface where it is associated with the T-tubules. In neither domain of the muscle surface does caveolin-3 colocalize with the glucose transporter GLUT4 and there is no evidence for internalization of the caveolae in muscle.",
keywords = "Animals, Caveolin 3, Caveolins, Membrane Proteins, Mice, Muscle Fibers, Skeletal, Muscle, Skeletal, Rabbits, Rats, Rats, Wistar",
author = "E Ralston and Thorkil Ploug",
note = "Copyright 1999 Academic Press.",
year = "1999",
month = feb,
day = "1",
doi = "10.1006/excr.1998.4305",
language = "English",
volume = "246",
pages = "510--5",
journal = "Experimental Cell Research",
issn = "0014-4827",
publisher = "Academic Press",
number = "2",

}

RIS

TY - JOUR

T1 - Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers

AU - Ralston, E

AU - Ploug, Thorkil

N1 - Copyright 1999 Academic Press.

PY - 1999/2/1

Y1 - 1999/2/1

N2 - Caveolae are abundant in skeletal muscle and their coat contains a specific isoform of caveolin, caveolin-3. It has been suggested that during muscle development, caveolin-3 is associated with the T-tubules, but that in adult muscle it is found on the plasma membrane only. We have studied the distribution of caveolin-3 in single skeletal muscle fibers from adult rat soleus by confocal immunofluorescence and by immunogold electron microscopy. We found that caveolin-3 occurs at the highest density on the plasma membrane but is also present in the core of the fibers, at the I-band/A-band interface where it is associated with the T-tubules. In neither domain of the muscle surface does caveolin-3 colocalize with the glucose transporter GLUT4 and there is no evidence for internalization of the caveolae in muscle.

AB - Caveolae are abundant in skeletal muscle and their coat contains a specific isoform of caveolin, caveolin-3. It has been suggested that during muscle development, caveolin-3 is associated with the T-tubules, but that in adult muscle it is found on the plasma membrane only. We have studied the distribution of caveolin-3 in single skeletal muscle fibers from adult rat soleus by confocal immunofluorescence and by immunogold electron microscopy. We found that caveolin-3 occurs at the highest density on the plasma membrane but is also present in the core of the fibers, at the I-band/A-band interface where it is associated with the T-tubules. In neither domain of the muscle surface does caveolin-3 colocalize with the glucose transporter GLUT4 and there is no evidence for internalization of the caveolae in muscle.

KW - Animals

KW - Caveolin 3

KW - Caveolins

KW - Membrane Proteins

KW - Mice

KW - Muscle Fibers, Skeletal

KW - Muscle, Skeletal

KW - Rabbits

KW - Rats

KW - Rats, Wistar

U2 - 10.1006/excr.1998.4305

DO - 10.1006/excr.1998.4305

M3 - Journal article

C2 - 9925767

VL - 246

SP - 510

EP - 515

JO - Experimental Cell Research

JF - Experimental Cell Research

SN - 0014-4827

IS - 2

ER -

ID: 123665754