Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study

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Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study. / Jorgensen, A. -H R.; Yao, Y.; Ghazanfar, M. N.; Ring, H. C.; Thomsen, S. F.

I: Journal of the European Academy of Dermatology and Venereology. Supplement, Bind 34, Nr. 3, 2020, s. 565-573.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Jorgensen, A-HR, Yao, Y, Ghazanfar, MN, Ring, HC & Thomsen, SF 2020, 'Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study', Journal of the European Academy of Dermatology and Venereology. Supplement, bind 34, nr. 3, s. 565-573. https://doi.org/10.1111/jdv.15904

APA

Jorgensen, A. -H. R., Yao, Y., Ghazanfar, M. N., Ring, H. C., & Thomsen, S. F. (2020). Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study. Journal of the European Academy of Dermatology and Venereology. Supplement, 34(3), 565-573. https://doi.org/10.1111/jdv.15904

Vancouver

Jorgensen A-HR, Yao Y, Ghazanfar MN, Ring HC, Thomsen SF. Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study. Journal of the European Academy of Dermatology and Venereology. Supplement. 2020;34(3):565-573. https://doi.org/10.1111/jdv.15904

Author

Jorgensen, A. -H R. ; Yao, Y. ; Ghazanfar, M. N. ; Ring, H. C. ; Thomsen, S. F. / Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study. I: Journal of the European Academy of Dermatology and Venereology. Supplement. 2020 ; Bind 34, Nr. 3. s. 565-573.

Bibtex

@article{7bbfeae4568a42298f6a76430c0022e0,
title = "Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study",
abstract = "AimTo examine the burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa (HS). MethodsInformation on HS and ten systemic comorbidities was obtained by interview and clinical examination, including blood pressure, body mass index (BMI) and blood samples, in a cohort of consecutive HS outpatients. ResultsA total of 302 patients were included. About 86.6{\%} had at least one comorbidity. The mean number of comorbidities per patient was 2.1. One or more cardiovascular comorbidities were observed in 76.5{\%} with evidence of substantial unawareness and undertreatment; 48.4{\%} had hypertension, 9.3{\%} had diabetes, 57.7{\%} had dyslipidaemia and 36.7{\%} were obese. About 6.6{\%} had inflammatory bowel disease, 6.3{\%} had arthritis, 29.5{\%} had a psychiatric diagnosis, 5.6{\%} had psoriasis, 7.9{\%} had obstructive lung disease, and 6.6{\%} had polycystic ovary syndrome. These comorbidities occurred at different time points in relation to the onset of HS with evidence of shared as well as differential risk factors. Age (per year), HR = 0.87 (0.79-0.96), P < 0.006, age of onset of HS (per year), HR = 1.26 (1.14-1.40), P < 0.001, male sex, HR = 2.51 (0.88-7.16), P = 0.086, Hurley stage III (vs. Hurley I + II), HR = 3.46 (1.25-9.58), P = 0.017, BMI (per unit), HR = 1.12 (1.04-1.20), P = 0.002, and blood glucose (per unit), HR = 1.27 (1.16-1.39), P < 0.001 were significant predictors for onset of diabetes. ConclusionThere is a substantial burden, unawareness and undertreatment of several systemic comorbidities in patients with HS. Comorbidities occur at different time points in relation to the onset of HS. This should lead to higher awareness among treating specialists.",
author = "Jorgensen, {A. -H R.} and Y. Yao and Ghazanfar, {M. N.} and Ring, {H. C.} and Thomsen, {S. F.}",
year = "2020",
doi = "10.1111/jdv.15904",
language = "English",
volume = "34",
pages = "565--573",
journal = "Journal of the European Academy of Dermatology and Venereology. Supplement",
issn = "0929-0168",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa: a hospital-based cohort study

AU - Jorgensen, A. -H R.

AU - Yao, Y.

AU - Ghazanfar, M. N.

AU - Ring, H. C.

AU - Thomsen, S. F.

PY - 2020

Y1 - 2020

N2 - AimTo examine the burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa (HS). MethodsInformation on HS and ten systemic comorbidities was obtained by interview and clinical examination, including blood pressure, body mass index (BMI) and blood samples, in a cohort of consecutive HS outpatients. ResultsA total of 302 patients were included. About 86.6% had at least one comorbidity. The mean number of comorbidities per patient was 2.1. One or more cardiovascular comorbidities were observed in 76.5% with evidence of substantial unawareness and undertreatment; 48.4% had hypertension, 9.3% had diabetes, 57.7% had dyslipidaemia and 36.7% were obese. About 6.6% had inflammatory bowel disease, 6.3% had arthritis, 29.5% had a psychiatric diagnosis, 5.6% had psoriasis, 7.9% had obstructive lung disease, and 6.6% had polycystic ovary syndrome. These comorbidities occurred at different time points in relation to the onset of HS with evidence of shared as well as differential risk factors. Age (per year), HR = 0.87 (0.79-0.96), P < 0.006, age of onset of HS (per year), HR = 1.26 (1.14-1.40), P < 0.001, male sex, HR = 2.51 (0.88-7.16), P = 0.086, Hurley stage III (vs. Hurley I + II), HR = 3.46 (1.25-9.58), P = 0.017, BMI (per unit), HR = 1.12 (1.04-1.20), P = 0.002, and blood glucose (per unit), HR = 1.27 (1.16-1.39), P < 0.001 were significant predictors for onset of diabetes. ConclusionThere is a substantial burden, unawareness and undertreatment of several systemic comorbidities in patients with HS. Comorbidities occur at different time points in relation to the onset of HS. This should lead to higher awareness among treating specialists.

AB - AimTo examine the burden, predictors and temporal relationships of comorbidities in patients with hidradenitis suppurativa (HS). MethodsInformation on HS and ten systemic comorbidities was obtained by interview and clinical examination, including blood pressure, body mass index (BMI) and blood samples, in a cohort of consecutive HS outpatients. ResultsA total of 302 patients were included. About 86.6% had at least one comorbidity. The mean number of comorbidities per patient was 2.1. One or more cardiovascular comorbidities were observed in 76.5% with evidence of substantial unawareness and undertreatment; 48.4% had hypertension, 9.3% had diabetes, 57.7% had dyslipidaemia and 36.7% were obese. About 6.6% had inflammatory bowel disease, 6.3% had arthritis, 29.5% had a psychiatric diagnosis, 5.6% had psoriasis, 7.9% had obstructive lung disease, and 6.6% had polycystic ovary syndrome. These comorbidities occurred at different time points in relation to the onset of HS with evidence of shared as well as differential risk factors. Age (per year), HR = 0.87 (0.79-0.96), P < 0.006, age of onset of HS (per year), HR = 1.26 (1.14-1.40), P < 0.001, male sex, HR = 2.51 (0.88-7.16), P = 0.086, Hurley stage III (vs. Hurley I + II), HR = 3.46 (1.25-9.58), P = 0.017, BMI (per unit), HR = 1.12 (1.04-1.20), P = 0.002, and blood glucose (per unit), HR = 1.27 (1.16-1.39), P < 0.001 were significant predictors for onset of diabetes. ConclusionThere is a substantial burden, unawareness and undertreatment of several systemic comorbidities in patients with HS. Comorbidities occur at different time points in relation to the onset of HS. This should lead to higher awareness among treating specialists.

U2 - 10.1111/jdv.15904

DO - 10.1111/jdv.15904

M3 - Journal article

C2 - 31442338

VL - 34

SP - 565

EP - 573

JO - Journal of the European Academy of Dermatology and Venereology. Supplement

JF - Journal of the European Academy of Dermatology and Venereology. Supplement

SN - 0929-0168

IS - 3

ER -

ID: 228370248