Association of maternal psoriasis and small for gestational age or preterm birth: a nationwide matched cohort study in 69 080 singleton infants

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Association of maternal psoriasis and small for gestational age or preterm birth : a nationwide matched cohort study in 69 080 singleton infants. / Johansen, Cæcilie Bachdal; Egeberg, Alexander; Jimenez-Solem, Espen; Skov, Lone; Thomsen, Simon Francis.

I: Clinical and Experimental Dermatology, Bind 47, Nr. 6, 2022, s. 1115-1123.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Johansen, CB, Egeberg, A, Jimenez-Solem, E, Skov, L & Thomsen, SF 2022, 'Association of maternal psoriasis and small for gestational age or preterm birth: a nationwide matched cohort study in 69 080 singleton infants', Clinical and Experimental Dermatology, bind 47, nr. 6, s. 1115-1123. https://doi.org/10.1111/ced.15105

APA

Johansen, C. B., Egeberg, A., Jimenez-Solem, E., Skov, L., & Thomsen, S. F. (2022). Association of maternal psoriasis and small for gestational age or preterm birth: a nationwide matched cohort study in 69 080 singleton infants. Clinical and Experimental Dermatology, 47(6), 1115-1123. https://doi.org/10.1111/ced.15105

Vancouver

Johansen CB, Egeberg A, Jimenez-Solem E, Skov L, Thomsen SF. Association of maternal psoriasis and small for gestational age or preterm birth: a nationwide matched cohort study in 69 080 singleton infants. Clinical and Experimental Dermatology. 2022;47(6):1115-1123. https://doi.org/10.1111/ced.15105

Author

Johansen, Cæcilie Bachdal ; Egeberg, Alexander ; Jimenez-Solem, Espen ; Skov, Lone ; Thomsen, Simon Francis. / Association of maternal psoriasis and small for gestational age or preterm birth : a nationwide matched cohort study in 69 080 singleton infants. I: Clinical and Experimental Dermatology. 2022 ; Bind 47, Nr. 6. s. 1115-1123.

Bibtex

@article{961f0b11f4b0485eb2951b7221204082,
title = "Association of maternal psoriasis and small for gestational age or preterm birth: a nationwide matched cohort study in 69 080 singleton infants",
abstract = "Background: Women with certain inflammatory diseases have an increased risk of giving birth to infants who are small for gestational age (SGA) or preterm birth (PTB), with maternal disease activity being the most important risk factor. However, previous studies investigating an association between psoriasis and SGA are scarce and have shown conflicting results. Aim: To investigate the association between maternal psoriasis and risk of SGA infants and PTB, respectively, both overall and stratified by psoriasis severity. Methods: This was a nationwide register-based matched cohort study of women with psoriasis matched 1 : 10 to women without psoriasis on age at delivery, body mass index and smoking status and with their first singleton infant born during the period 2004–2017. Odds ratio (OR) and 95% CI were calculated in conditional logistic regression models adjusted for known risk factors. Results: From 516 063 deliveries, we identified 6282 women with psoriasis and 62 798 matched women without psoriasis. The risk of SGA and PTB was similar in women with psoriasis and matched controls: adjusted OR (aOR) = 1.07 (95% CI 0.98–1.17) and aOR = 1.05 (95% CI 0.93–1.19), respectively. The risk of term SGA was increased in women with psoriasis (aOR 1.11; 95% CI 1.01–1.22) compared with matched controls. Conclusion: Maternal psoriasis was not associated with increased risk of SGA or PTB. Risk of term SGA was slightly increased in women with a history of psoriasis compared with matched controls, however; these infants are likely to be constitutionally small with no increased risk of perinatal morbidity and mortality.",
author = "Johansen, {C{\ae}cilie Bachdal} and Alexander Egeberg and Espen Jimenez-Solem and Lone Skov and Thomsen, {Simon Francis}",
note = "Publisher Copyright: {\textcopyright} 2022 British Association of Dermatologists.",
year = "2022",
doi = "10.1111/ced.15105",
language = "English",
volume = "47",
pages = "1115--1123",
journal = "Transactions of the St. John's Hospital Dermatological Society",
issn = "0307-6938",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Association of maternal psoriasis and small for gestational age or preterm birth

T2 - a nationwide matched cohort study in 69 080 singleton infants

AU - Johansen, Cæcilie Bachdal

AU - Egeberg, Alexander

AU - Jimenez-Solem, Espen

AU - Skov, Lone

AU - Thomsen, Simon Francis

N1 - Publisher Copyright: © 2022 British Association of Dermatologists.

PY - 2022

Y1 - 2022

N2 - Background: Women with certain inflammatory diseases have an increased risk of giving birth to infants who are small for gestational age (SGA) or preterm birth (PTB), with maternal disease activity being the most important risk factor. However, previous studies investigating an association between psoriasis and SGA are scarce and have shown conflicting results. Aim: To investigate the association between maternal psoriasis and risk of SGA infants and PTB, respectively, both overall and stratified by psoriasis severity. Methods: This was a nationwide register-based matched cohort study of women with psoriasis matched 1 : 10 to women without psoriasis on age at delivery, body mass index and smoking status and with their first singleton infant born during the period 2004–2017. Odds ratio (OR) and 95% CI were calculated in conditional logistic regression models adjusted for known risk factors. Results: From 516 063 deliveries, we identified 6282 women with psoriasis and 62 798 matched women without psoriasis. The risk of SGA and PTB was similar in women with psoriasis and matched controls: adjusted OR (aOR) = 1.07 (95% CI 0.98–1.17) and aOR = 1.05 (95% CI 0.93–1.19), respectively. The risk of term SGA was increased in women with psoriasis (aOR 1.11; 95% CI 1.01–1.22) compared with matched controls. Conclusion: Maternal psoriasis was not associated with increased risk of SGA or PTB. Risk of term SGA was slightly increased in women with a history of psoriasis compared with matched controls, however; these infants are likely to be constitutionally small with no increased risk of perinatal morbidity and mortality.

AB - Background: Women with certain inflammatory diseases have an increased risk of giving birth to infants who are small for gestational age (SGA) or preterm birth (PTB), with maternal disease activity being the most important risk factor. However, previous studies investigating an association between psoriasis and SGA are scarce and have shown conflicting results. Aim: To investigate the association between maternal psoriasis and risk of SGA infants and PTB, respectively, both overall and stratified by psoriasis severity. Methods: This was a nationwide register-based matched cohort study of women with psoriasis matched 1 : 10 to women without psoriasis on age at delivery, body mass index and smoking status and with their first singleton infant born during the period 2004–2017. Odds ratio (OR) and 95% CI were calculated in conditional logistic regression models adjusted for known risk factors. Results: From 516 063 deliveries, we identified 6282 women with psoriasis and 62 798 matched women without psoriasis. The risk of SGA and PTB was similar in women with psoriasis and matched controls: adjusted OR (aOR) = 1.07 (95% CI 0.98–1.17) and aOR = 1.05 (95% CI 0.93–1.19), respectively. The risk of term SGA was increased in women with psoriasis (aOR 1.11; 95% CI 1.01–1.22) compared with matched controls. Conclusion: Maternal psoriasis was not associated with increased risk of SGA or PTB. Risk of term SGA was slightly increased in women with a history of psoriasis compared with matched controls, however; these infants are likely to be constitutionally small with no increased risk of perinatal morbidity and mortality.

U2 - 10.1111/ced.15105

DO - 10.1111/ced.15105

M3 - Journal article

C2 - 35015913

AN - SCOPUS:85128251722

VL - 47

SP - 1115

EP - 1123

JO - Transactions of the St. John's Hospital Dermatological Society

JF - Transactions of the St. John's Hospital Dermatological Society

SN - 0307-6938

IS - 6

ER -

ID: 311119302