Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis?

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Standard

Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis? / Stavnem, Dorte Marie; Hadad, Rakin; Larsen, Bjørn Strøier; Nielsen, Olav Wendelboe; Frederiksen, Mark Aplin; Davidsen, Ulla; Højbjerg, Søren; Karlsen, Finn Michael; Vall-Lamora, Maria Helena Domínguez; Rasmusen, Hanne Kruuse; Sajadieh, Ahmad.

I: Cardiology, Bind 147, 2022, s. 57–61.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Stavnem, DM, Hadad, R, Larsen, BS, Nielsen, OW, Frederiksen, MA, Davidsen, U, Højbjerg, S, Karlsen, FM, Vall-Lamora, MHD, Rasmusen, HK & Sajadieh, A 2022, 'Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis?', Cardiology, bind 147, s. 57–61. https://doi.org/10.1159/000520183

APA

Stavnem, D. M., Hadad, R., Larsen, B. S., Nielsen, O. W., Frederiksen, M. A., Davidsen, U., Højbjerg, S., Karlsen, F. M., Vall-Lamora, M. H. D., Rasmusen, H. K., & Sajadieh, A. (2022). Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis? Cardiology, 147, 57–61. https://doi.org/10.1159/000520183

Vancouver

Stavnem DM, Hadad R, Larsen BS, Nielsen OW, Frederiksen MA, Davidsen U o.a. Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis? Cardiology. 2022;147:57–61. https://doi.org/10.1159/000520183

Author

Stavnem, Dorte Marie ; Hadad, Rakin ; Larsen, Bjørn Strøier ; Nielsen, Olav Wendelboe ; Frederiksen, Mark Aplin ; Davidsen, Ulla ; Højbjerg, Søren ; Karlsen, Finn Michael ; Vall-Lamora, Maria Helena Domínguez ; Rasmusen, Hanne Kruuse ; Sajadieh, Ahmad. / Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis?. I: Cardiology. 2022 ; Bind 147. s. 57–61.

Bibtex

@article{b80181f8b4a14a4abf36c397d3962be5,
title = "Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis?",
abstract = "Background: In patients with atrial fibrillation (AF), the long-term prognosis of long electrocardiographic pauses in the ventricular action is not well studied. Methods: Consecutive Holter recordings in patients with AF (n = 200) between 2009 and 2011 were evaluated, focusing on pauses of at least 2.5 s. Outcomes of interest were all-cause mortality and pacemaker implantation. Results: Forty-three patients (21.5%) had pauses with a mean of 3.2 s and an SD of 0.9 s. After a median follow-up of 99 months (ranging 89–111), 47% (20/43) of the patients with and 45% (70/157) without pauses were deceased. Pauses of ≥2.5 s did not constitute a risk of increased mortality: HR = 0.75 (95% CI: 0.34–1.66); p = 0.48, neither did pauses of ≥3.0 s: HR = 0.43 (95% CI: 0.06–3.20); p = 0.41. Sixteen percent of patients with pauses underwent pacemaker implantation during follow-up. Only pauses in patients referred to Holter due to syncope and/or dizzy spells were associated with an increased risk of pacemaker treatment: HR = 4.7 (95% CI: 1.4–15.9), p = 0.014, adjusted for age, sex, and rate-limiting medication. Conclusion: In patients with AF, prolonged electrocardiographic pauses of ≥2.5 s or ≥3.0 s are not a marker for increased mortality in this real-life clinical study.",
author = "Stavnem, {Dorte Marie} and Rakin Hadad and Larsen, {Bj{\o}rn Str{\o}ier} and Nielsen, {Olav Wendelboe} and Frederiksen, {Mark Aplin} and Ulla Davidsen and S{\o}ren H{\o}jbjerg and Karlsen, {Finn Michael} and Vall-Lamora, {Maria Helena Dom{\'i}nguez} and Rasmusen, {Hanne Kruuse} and Ahmad Sajadieh",
year = "2022",
doi = "10.1159/000520183",
language = "English",
volume = "147",
pages = "57–61",
journal = "Cardiologia",
issn = "0008-6312",
publisher = "S Karger AG",

}

RIS

TY - JOUR

T1 - Are Prolonged Ventricular Pauses in Atrial Fibrillation a Marker of Poor Prognosis?

AU - Stavnem, Dorte Marie

AU - Hadad, Rakin

AU - Larsen, Bjørn Strøier

AU - Nielsen, Olav Wendelboe

AU - Frederiksen, Mark Aplin

AU - Davidsen, Ulla

AU - Højbjerg, Søren

AU - Karlsen, Finn Michael

AU - Vall-Lamora, Maria Helena Domínguez

AU - Rasmusen, Hanne Kruuse

AU - Sajadieh, Ahmad

PY - 2022

Y1 - 2022

N2 - Background: In patients with atrial fibrillation (AF), the long-term prognosis of long electrocardiographic pauses in the ventricular action is not well studied. Methods: Consecutive Holter recordings in patients with AF (n = 200) between 2009 and 2011 were evaluated, focusing on pauses of at least 2.5 s. Outcomes of interest were all-cause mortality and pacemaker implantation. Results: Forty-three patients (21.5%) had pauses with a mean of 3.2 s and an SD of 0.9 s. After a median follow-up of 99 months (ranging 89–111), 47% (20/43) of the patients with and 45% (70/157) without pauses were deceased. Pauses of ≥2.5 s did not constitute a risk of increased mortality: HR = 0.75 (95% CI: 0.34–1.66); p = 0.48, neither did pauses of ≥3.0 s: HR = 0.43 (95% CI: 0.06–3.20); p = 0.41. Sixteen percent of patients with pauses underwent pacemaker implantation during follow-up. Only pauses in patients referred to Holter due to syncope and/or dizzy spells were associated with an increased risk of pacemaker treatment: HR = 4.7 (95% CI: 1.4–15.9), p = 0.014, adjusted for age, sex, and rate-limiting medication. Conclusion: In patients with AF, prolonged electrocardiographic pauses of ≥2.5 s or ≥3.0 s are not a marker for increased mortality in this real-life clinical study.

AB - Background: In patients with atrial fibrillation (AF), the long-term prognosis of long electrocardiographic pauses in the ventricular action is not well studied. Methods: Consecutive Holter recordings in patients with AF (n = 200) between 2009 and 2011 were evaluated, focusing on pauses of at least 2.5 s. Outcomes of interest were all-cause mortality and pacemaker implantation. Results: Forty-three patients (21.5%) had pauses with a mean of 3.2 s and an SD of 0.9 s. After a median follow-up of 99 months (ranging 89–111), 47% (20/43) of the patients with and 45% (70/157) without pauses were deceased. Pauses of ≥2.5 s did not constitute a risk of increased mortality: HR = 0.75 (95% CI: 0.34–1.66); p = 0.48, neither did pauses of ≥3.0 s: HR = 0.43 (95% CI: 0.06–3.20); p = 0.41. Sixteen percent of patients with pauses underwent pacemaker implantation during follow-up. Only pauses in patients referred to Holter due to syncope and/or dizzy spells were associated with an increased risk of pacemaker treatment: HR = 4.7 (95% CI: 1.4–15.9), p = 0.014, adjusted for age, sex, and rate-limiting medication. Conclusion: In patients with AF, prolonged electrocardiographic pauses of ≥2.5 s or ≥3.0 s are not a marker for increased mortality in this real-life clinical study.

U2 - 10.1159/000520183

DO - 10.1159/000520183

M3 - Journal article

C2 - 34662878

VL - 147

SP - 57

EP - 61

JO - Cardiologia

JF - Cardiologia

SN - 0008-6312

ER -

ID: 303688925