A comparative, BAC end sequence enabled map of the genome of the American mink (Neovison vison)

Publikation: Bidrag til tidsskriftTidsskriftartikel

  • Bernhard F. Benkel
  • Amanda Smith
  • Christensen, Knud Arnbjerg
  • Razvan Marian Anistoroaei
  • Ye Zhang
  • Christoph W. Sensen
  • Hossain Farid
  • Lyn Paterson
  • Ronald M. Teather
In this report we present the results of the analysis of approximately 2.7 Mb of genomic information for the American mink (Neovison vison) derived through BAC end sequencing. Our study, which encompasses approximately 1/1000th of the mink genome, suggests that simple sequence repeats (SSRs) are less common in the mink than in the human genome, whereas the average GC content of the mink genome is slightly higher than that of its human counterpart. The 2.7 Mb mink genomic dataset also contained 2,416 repeat elements (retroids and DNA transposons) occupying almost 31% of the sequence space. Among repeat elements, LINEs were over-represented and endogenous viruses (aka LTRs) under-represented in comparison to the human genome. Finally, we present a virtual map of the mink genome constructed with reference to the human and canine genome assemblies using a comparative genomics approach and incorporating over 200 mink BESs with unique hits to the human genome.
OriginalsprogEngelsk
TidsskriftGenes and Genomics
Vol/bind34
Udgave nummer1
Sider (fra-til)83-91
Antal sider9
ISSN1976-9571
DOI
StatusUdgivet - 2012

    Forskningsområder

  • Det tidligere LIFE - American mink, BAC end sequencing, Comparatve mapping, Structural genomics

ID: 37765863