Tumor angiogenesis--a new therapeutic target in gliomas

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Tumor angiogenesis--a new therapeutic target in gliomas. / Lund, E L; Spang-Thomsen, M; Skovgaard-Poulsen, H; Kristjansen, P E.

I: Acta Neurologica Scandinavica, Bind 97, Nr. 1, 1998, s. 52-62.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lund, EL, Spang-Thomsen, M, Skovgaard-Poulsen, H & Kristjansen, PE 1998, 'Tumor angiogenesis--a new therapeutic target in gliomas', Acta Neurologica Scandinavica, bind 97, nr. 1, s. 52-62.

APA

Lund, E. L., Spang-Thomsen, M., Skovgaard-Poulsen, H., & Kristjansen, P. E. (1998). Tumor angiogenesis--a new therapeutic target in gliomas. Acta Neurologica Scandinavica, 97(1), 52-62.

Vancouver

Lund EL, Spang-Thomsen M, Skovgaard-Poulsen H, Kristjansen PE. Tumor angiogenesis--a new therapeutic target in gliomas. Acta Neurologica Scandinavica. 1998;97(1):52-62.

Author

Lund, E L ; Spang-Thomsen, M ; Skovgaard-Poulsen, H ; Kristjansen, P E. / Tumor angiogenesis--a new therapeutic target in gliomas. I: Acta Neurologica Scandinavica. 1998 ; Bind 97, Nr. 1. s. 52-62.

Bibtex

@article{f62b338064b811de8bc9000ea68e967b,
title = "Tumor angiogenesis--a new therapeutic target in gliomas",
abstract = "Tumor growth is critically dependent on angiogenesis, which is sprouting of new vessels from pre-existing vasculature. This process is regulated by inducers and inhibitors released from tumor cells, endothelial cells, and macrophages. Brain tumors, especially glioblastoma multiforme, have significant angiogenic activity primarily by the expression of the angiogenic factor VEGF Anti-angiogenic therapy represents a new promising therapeutic modality in solid tumors. Several agents are currently under evaluation in clinical trials. The present review describes the principal inducers and inhibitors of angiogenesis in tumors and summarizes what is known about their mechanisms of action in relation to CNS tumors. Potential areas for clinical use are also discussed.",
author = "Lund, {E L} and M Spang-Thomsen and H Skovgaard-Poulsen and Kristjansen, {P E}",
note = "Keywords: Brain Neoplasms; Glioma; Humans; Neovascularization, Pathologic",
year = "1998",
language = "English",
volume = "97",
pages = "52--62",
journal = "Acta Neurologica Scandinavica",
issn = "0001-6314",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Tumor angiogenesis--a new therapeutic target in gliomas

AU - Lund, E L

AU - Spang-Thomsen, M

AU - Skovgaard-Poulsen, H

AU - Kristjansen, P E

N1 - Keywords: Brain Neoplasms; Glioma; Humans; Neovascularization, Pathologic

PY - 1998

Y1 - 1998

N2 - Tumor growth is critically dependent on angiogenesis, which is sprouting of new vessels from pre-existing vasculature. This process is regulated by inducers and inhibitors released from tumor cells, endothelial cells, and macrophages. Brain tumors, especially glioblastoma multiforme, have significant angiogenic activity primarily by the expression of the angiogenic factor VEGF Anti-angiogenic therapy represents a new promising therapeutic modality in solid tumors. Several agents are currently under evaluation in clinical trials. The present review describes the principal inducers and inhibitors of angiogenesis in tumors and summarizes what is known about their mechanisms of action in relation to CNS tumors. Potential areas for clinical use are also discussed.

AB - Tumor growth is critically dependent on angiogenesis, which is sprouting of new vessels from pre-existing vasculature. This process is regulated by inducers and inhibitors released from tumor cells, endothelial cells, and macrophages. Brain tumors, especially glioblastoma multiforme, have significant angiogenic activity primarily by the expression of the angiogenic factor VEGF Anti-angiogenic therapy represents a new promising therapeutic modality in solid tumors. Several agents are currently under evaluation in clinical trials. The present review describes the principal inducers and inhibitors of angiogenesis in tumors and summarizes what is known about their mechanisms of action in relation to CNS tumors. Potential areas for clinical use are also discussed.

M3 - Journal article

C2 - 9482679

VL - 97

SP - 52

EP - 62

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

SN - 0001-6314

IS - 1

ER -

ID: 12870105